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The map label for this gene is manX [C]

Identifier: 116871446

GI number: 116871446

Start: 25773

End: 26174

Strand: Direct

Name: manX [C]

Synonym: lwe0024

Alternate gene names: 116871446

Gene position: 25773-26174 (Clockwise)

Preceding gene: 116871445

Following gene: 116871447

Centisome position: 0.92

GC content: 40.3

Gene sequence:

>402_bases
TTGAATTATATTATCGCAGCACATGGCCGGTACGCGCAGGAAGTAAAAAATAGCTGCCAGATGATTACCGGCCAAACAAC
GAATATCGCAGCAGTTACTTTTACCGAAGACATGGGGGTGACGGATGTATTAGAGAGCTACAATGCTGTTTATTCACCTG
AAAATGAAACCGTTATCATAGTAGATATTGTGGGTGGGACACCTTGTAATGCAGCGCAAATGTTTCGTGCAAAATATCCT
GAAATAAAGATAGTATCAGGTTTATCACTAGGATTAATTATCCCGCTTAGTCTGGGAGAAAGCTTAGAAGGAGCGATTAT
TGGCGCACAAGAAAATATTCAATTTGTGGAATTGAAAGCAAATAATTCGACAGTAAGCGATGATGGAGAGGAAGAGGACT
AA

Upstream 100 bases:

>100_bases
ACCAGAGGGAAAGCCCTATGAATATATTGAAAGCTATTTACGACATAATTTTTACTCTATTGAAATTGAAAAGAAAAAAC
AATAGAAAGGAGATCATTAC

Downstream 100 bases:

>100_bases
TGGGAAGTAACGGAATTAAACATGTACGTGTTGATGAAAGACTAATTCATGGACAAGTAGCAACAATGTGGACTAATACC
ATAAAGGCAACGCGAATTAT

Product: PTS system, fructose family, IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: PTS System Fructose Family IIA Component; PTS System Transporter Subunit IIAB

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MNYIIAAHGRYAQEVKNSCQMITGQTTNIAAVTFTEDMGVTDVLESYNAVYSPENETVIIVDIVGGTPCNAAQMFRAKYP
EIKIVSGLSLGLIIPLSLGESLEGAIIGAQENIQFVELKANNSTVSDDGEEED

Sequences:

>Translated_133_residues
MNYIIAAHGRYAQEVKNSCQMITGQTTNIAAVTFTEDMGVTDVLESYNAVYSPENETVIIVDIVGGTPCNAAQMFRAKYP
EIKIVSGLSLGLIIPLSLGESLEGAIIGAQENIQFVELKANNSTVSDDGEEED
>Mature_133_residues
MNYIIAAHGRYAQEVKNSCQMITGQTTNIAAVTFTEDMGVTDVLESYNAVYSPENETVIIVDIVGGTPCNAAQMFRAKYP
EIKIVSGLSLGLIIPLSLGESLEGAIIGAQENIQFVELKANNSTVSDDGEEED

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 14276; Mature: 14276

Theoretical pI: Translated: 3.84; Mature: 3.84

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIIAAHGRYAQEVKNSCQMITGQTTNIAAVTFTEDMGVTDVLESYNAVYSPENETVII
CCEEEECCCCHHHHHHHHHEEEECCCCEEEEEEEECCCCHHHHHHHCCCEECCCCCEEEE
VDIVGGTPCNAAQMFRAKYPEIKIVSGLSLGLIIPLSLGESLEGAIIGAQENIQFVELKA
EECCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCCCEEEECCCCEEEEEEEC
NNSTVSDDGEEED
CCCCCCCCCCCCC
>Mature Secondary Structure
MNYIIAAHGRYAQEVKNSCQMITGQTTNIAAVTFTEDMGVTDVLESYNAVYSPENETVII
CCEEEECCCCHHHHHHHHHEEEECCCCEEEEEEEECCCCHHHHHHHCCCEECCCCCEEEE
VDIVGGTPCNAAQMFRAKYPEIKIVSGLSLGLIIPLSLGESLEGAIIGAQENIQFVELKA
EECCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCCCEEEECCCCEEEEEEEC
NNSTVSDDGEEED
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA