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The map label for this gene is fmt

Identifier: 116691144

GI number: 116691144

Start: 3441786

End: 3442778

Strand: Reverse

Name: fmt

Synonym: Bcen2424_3126

Alternate gene names: 116691144

Gene position: 3442778-3441786 (Counterclockwise)

Preceding gene: 116691145

Following gene: 116691143

Centisome position: 98.82

GC content: 72.81

Gene sequence:

>993_bases
ATGACCCATACGTTGCGCGTGATTTTTGCCGGCACGCCGGAATTCGCCGCGGCCGCCCTGGCCGCGATCCACAAGGCCGG
TTTCCCGGTGCCGCTCGTGCTGACCCAGCCCGATCGCCCGGCCGGGCGCGGGATGAAGCTCCAGGCGAGCGCCGTGAAGC
GCTACGCCGTCGAGCACGGGATGGCCGTCGCGCAGCCGCCGTCGCTGCGCCGCGCGGGCAAGTACCCGGCGGAGGCGGCC
GACGCGATCGAGTTGCTGCGCACGACGCCGCACGACGTGATGGTGGTGGCCGCGTACGGCCTGCTGCTGCCGCAGGAAGT
GCTCGACATCCCGCGCGCCGGCTGCATCAACATTCACGCATCGCTGCTGCCGCGCTGGCGCGGCGCGGCGCCGATCCATC
GTGCGATCGAGGCCGGCGACGCCGAGACGGGCGTCACGCTGATGCAGATGGACGTCGGCCTCGACACCGGCGCGATGATC
GAGGAGGCGCGCATCGCGATCGCGCCTGACGATACGACCGCGACGCTGCACGACCGCCTCGCCGCCGACGGCGCGCGGCT
GATCGTCGACGCGCTCGTGCGGCTCGAGCGCGACGGGACGCTGCCGGCGACGCCGCAGCCGGCCGACGGCGTGACCTACG
CGGAAAAGATCGGCAAGCATGAAGCGGCGCTCGACTGGCGCAAGCCTGCGGACGTACTCGCGCGCCAGGTGCGTGCGTTC
GACCCGTTCCCGGGCGGCGTCGCGACGCTTGACGGCGCGGCCATCAAGCTGTGGGCGGCCGAGCCCGTGGCGACGGATGG
CACGATTGCCAGCGCGGCGCCCGGCACGATCGTCGAAGCCGCGCCGGAAGGCGTGGTGGTCGCATGCGGCAGCGGCGCGC
TGCGCGTCACCCAGCTGCAGAAGCCCGGCGGAAAACGGCTGCCTGCACGCGAATTCCTCGCCGGTTCGCCGCTCGCCGCC
GGCCAGCGTTTCGCGCTACCCGACGTCGACTGA

Upstream 100 bases:

>100_bases
TATCTGTCGCCGCTCAAGCAGACGCGCATCAAGACGAAGATGAAGAAACTCGAACGCGCGATGTAATGCGCGTGCGCCCA
GCCCGACCCCGAACGCTGTC

Downstream 100 bases:

>100_bases
CAGGCCTGAGCGCCATTCGACCCGGTCTGCCGGCCCGGCGCAACTGGCCGGACGGCCGAGTCGCGCGGGGCGGCAGGCAC
GCGTAGAATTTCCCTGCGCT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTHTLRVIFAGTPEFAAAALAAIHKAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHGMAVAQPPSLRRAGKYPAEAA
DAIELLRTTPHDVMVVAAYGLLLPQEVLDIPRAGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDVGLDTGAMI
EEARIAIAPDDTTATLHDRLAADGARLIVDALVRLERDGTLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
DPFPGGVATLDGAAIKLWAAEPVATDGTIASAAPGTIVEAAPEGVVVACGSGALRVTQLQKPGGKRLPAREFLAGSPLAA
GQRFALPDVD

Sequences:

>Translated_330_residues
MTHTLRVIFAGTPEFAAAALAAIHKAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHGMAVAQPPSLRRAGKYPAEAA
DAIELLRTTPHDVMVVAAYGLLLPQEVLDIPRAGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDVGLDTGAMI
EEARIAIAPDDTTATLHDRLAADGARLIVDALVRLERDGTLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
DPFPGGVATLDGAAIKLWAAEPVATDGTIASAAPGTIVEAAPEGVVVACGSGALRVTQLQKPGGKRLPAREFLAGSPLAA
GQRFALPDVD
>Mature_329_residues
THTLRVIFAGTPEFAAAALAAIHKAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHGMAVAQPPSLRRAGKYPAEAAD
AIELLRTTPHDVMVVAAYGLLLPQEVLDIPRAGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDVGLDTGAMIE
EARIAIAPDDTTATLHDRLAADGARLIVDALVRLERDGTLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAFD
PFPGGVATLDGAAIKLWAAEPVATDGTIASAAPGTIVEAAPEGVVVACGSGALRVTQLQKPGGKRLPAREFLAGSPLAAG
QRFALPDVD

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family

Homologues:

Organism=Homo sapiens, GI238814322, Length=326, Percent_Identity=28.8343558282209, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI21614513, Length=323, Percent_Identity=27.5541795665635, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI164663775, Length=245, Percent_Identity=31.8367346938775, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1789683, Length=313, Percent_Identity=49.8402555910543, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI1788589, Length=321, Percent_Identity=30.2180685358255, Blast_Score=137, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=325, Percent_Identity=26.7692307692308, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI45550868, Length=322, Percent_Identity=29.5031055900621, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571984, Length=233, Percent_Identity=33.0472103004292, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24585660, Length=325, Percent_Identity=24.3076923076923, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FMT_BURCA (Q1BSJ4)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_622384.1
- ProteinModelPortal:   Q1BSJ4
- SMR:   Q1BSJ4
- STRING:   Q1BSJ4
- GeneID:   4093252
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_2512
- eggNOG:   COG0223
- HOGENOM:   HBG571560
- OMA:   IMQMDEG
- ProtClustDB:   PRK00005
- BioCyc:   BCEN331271:BCEN_2512-MONOMER
- HAMAP:   MF_00182
- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- PANTHER:   PTHR11138
- TIGRFAMs:   TIGR00460

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.9

Molecular weight: Translated: 34443; Mature: 34312

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTLRVIFAGTPEFAAAALAAIHKAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHG
CCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHC
MAVAQPPSLRRAGKYPAEAADAIELLRTTPHDVMVVAAYGLLLPQEVLDIPRAGCINIHA
CEECCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHCCCCCCEEEEHH
SLLPRWRGAAPIHRAIEAGDAETGVTLMQMDVGLDTGAMIEEARIAIAPDDTTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCEEEECCCCCHHHHHHHH
AADGARLIVDALVRLERDGTLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
HCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHC
DPFPGGVATLDGAAIKLWAAEPVATDGTIASAAPGTIVEAAPEGVVVACGSGALRVTQLQ
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCEEEEEEC
KPGGKRLPAREFLAGSPLAAGQRFALPDVD
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THTLRVIFAGTPEFAAAALAAIHKAGFPVPLVLTQPDRPAGRGMKLQASAVKRYAVEHG
CCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHC
MAVAQPPSLRRAGKYPAEAADAIELLRTTPHDVMVVAAYGLLLPQEVLDIPRAGCINIHA
CEECCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHCCCCCCEEEEHH
SLLPRWRGAAPIHRAIEAGDAETGVTLMQMDVGLDTGAMIEEARIAIAPDDTTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCEEEECCCCCHHHHHHHH
AADGARLIVDALVRLERDGTLPATPQPADGVTYAEKIGKHEAALDWRKPADVLARQVRAF
HCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHCCCCCCHHHHHHHHHHC
DPFPGGVATLDGAAIKLWAAEPVATDGTIASAAPGTIVEAAPEGVVVACGSGALRVTQLQ
CCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCEEEEEEC
KPGGKRLPAREFLAGSPLAAGQRFALPDVD
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA