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The map label for this gene is leuE [H]

Identifier: 116691143

GI number: 116691143

Start: 3441025

End: 3441666

Strand: Reverse

Name: leuE [H]

Synonym: Bcen2424_3125

Alternate gene names: 116691143

Gene position: 3441666-3441025 (Counterclockwise)

Preceding gene: 116691144

Following gene: 116691142

Centisome position: 98.79

GC content: 67.45

Gene sequence:

>642_bases
ATGTTCGGCATCACCCATTTCGGCTTCTTCGTGTTCGCGGTTTTCCTGCTGAACATCACGCCCGGCCCCGATACGGCCTA
CATCGTCGGCCGCAGCGTCGCGCAGGGGCGCGGCGCGGGGCTGATGTCGGCGTTCGGCATTTCGGCCGGCTGCTGCGTCC
ACGCGCTCGCCTGCGCATTCGGCCTCACCGCGCTGCTGGCCGCGTCGGCCACCGCGTTCACGGTGATCAAGCTGGTCGGC
GCCGCGTACCTGATCTATCTCGGCGTGCGGATGATCATCGCGAAGCAGGCCGCCGCGCCGTCGGGCGCCGCAGCCGCGCA
GGCCGCGGCCGCCAAGCCGCTGCGCCAGCTGTTCATGCAGGGTTTCTGGACCAACGTGCTGAATCCGAAGGTCGTGCTGT
TCTTCGTGTCGTTCTTCCCGCAGTTCGTGTCGGCCGACAGTCCGCACAAGGCCTGGGCGTTCCTGACCCTCGGCGCGGTG
TTCGTCGCGATGAGCACGGTCTGGACGAGCCTGGTTGCATGGGTGGCGGGCAGCGTCACGCAGCGCTTTTCCGGCAAGCC
GGGCGTCAAGAAGTGGCTCGATCGCACGGTCGGTAGCGCTTTCGTCGGCCTCGGTCTTCGTCTGGCAGCTTCGCAACGCT
GA

Upstream 100 bases:

>100_bases
ACCCGGTCTGCCGGCCCGGCGCAACTGGCCGGACGGCCGAGTCGCGCGGGGCGGCAGGCACGCGTAGAATTTCCCTGCGC
TCCCCGGTTTCGAGGTTTTC

Downstream 100 bases:

>100_bases
GATTGAATTTTTCCGGCAAGACCTTATCTAACAAATCGCTTACAATTTTCCGCCGTGCCCTGTGATGCGCGGCGGGTCCC
CTGACGGATAAGGAGTGGGT

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MFGITHFGFFVFAVFLLNITPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAFGLTALLAASATAFTVIKLVG
AAYLIYLGVRMIIAKQAAAPSGAAAAQAAAAKPLRQLFMQGFWTNVLNPKVVLFFVSFFPQFVSADSPHKAWAFLTLGAV
FVAMSTVWTSLVAWVAGSVTQRFSGKPGVKKWLDRTVGSAFVGLGLRLAASQR

Sequences:

>Translated_213_residues
MFGITHFGFFVFAVFLLNITPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAFGLTALLAASATAFTVIKLVG
AAYLIYLGVRMIIAKQAAAPSGAAAAQAAAAKPLRQLFMQGFWTNVLNPKVVLFFVSFFPQFVSADSPHKAWAFLTLGAV
FVAMSTVWTSLVAWVAGSVTQRFSGKPGVKKWLDRTVGSAFVGLGLRLAASQR
>Mature_213_residues
MFGITHFGFFVFAVFLLNITPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAFGLTALLAASATAFTVIKLVG
AAYLIYLGVRMIIAKQAAAPSGAAAAQAAAAKPLRQLFMQGFWTNVLNPKVVLFFVSFFPQFVSADSPHKAWAFLTLGAV
FVAMSTVWTSLVAWVAGSVTQRFSGKPGVKKWLDRTVGSAFVGLGLRLAASQR

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=209, Percent_Identity=28.7081339712919, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI48994979, Length=212, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994978, Length=195, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786522, Length=161, Percent_Identity=31.055900621118, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22318; Mature: 22318

Theoretical pI: Translated: 11.23; Mature: 11.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGITHFGFFVFAVFLLNITPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAF
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHCCCCCCHHHHHCCCHHHHHHHHHHHH
GLTALLAASATAFTVIKLVGAAYLIYLGVRMIIAKQAAAPSGAAAAQAAAAKPLRQLFMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GFWTNVLNPKVVLFFVSFFPQFVSADSPHKAWAFLTLGAVFVAMSTVWTSLVAWVAGSVT
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRFSGKPGVKKWLDRTVGSAFVGLGLRLAASQR
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFGITHFGFFVFAVFLLNITPGPDTAYIVGRSVAQGRGAGLMSAFGISAGCCVHALACAF
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHCCCCCCHHHHHCCCHHHHHHHHHHHH
GLTALLAASATAFTVIKLVGAAYLIYLGVRMIIAKQAAAPSGAAAAQAAAAKPLRQLFMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GFWTNVLNPKVVLFFVSFFPQFVSADSPHKAWAFLTLGAVFVAMSTVWTSLVAWVAGSVT
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRFSGKPGVKKWLDRTVGSAFVGLGLRLAASQR
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA