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The map label for this gene is queD [H]

Identifier: 116691135

GI number: 116691135

Start: 3432350

End: 3432802

Strand: Reverse

Name: queD [H]

Synonym: Bcen2424_3117

Alternate gene names: 116691135

Gene position: 3432802-3432350 (Counterclockwise)

Preceding gene: 116691136

Following gene: 116691134

Centisome position: 98.53

GC content: 65.34

Gene sequence:

>453_bases
GTGCTGATTACCCGAAAACTCGAATTCGACGCGGGCCACCGCATTCCCGATCACCGCAGCCAGTGCAGGAACCTGCACGG
CCATCGCTACGTGCTCGAAATCACGCTGCGCGGCGATCTCGTCGATACCGAGGGGGCGCCCGACCGCGGCATGGTGATGG
ATTTCGCCGACGTGAAGGCGCTCGCGATGGAGCACCTCGTCAGCAAGTGGGACCACGCGTTTCTGGTCTATGCGCGCGAC
GACGTCGTGCGCTCGTTCCTCGAGCAGATGGCCGACCACAAGACGGTCGTGATCGACCGGATCCCGACCGTCGAGAACCT
CGCGGCGATCGCGTTCGACCTCCTCGCGAACGTGTACGACGCGCACTACGGCGTGAACTTGCGCCTCGAGCGCGTGCGGC
TGTACGAAACGCCGAACTGCTGGGCCGACGTTGAGCGCCAGCCCGGCCGCTGA

Upstream 100 bases:

>100_bases
GAAGCTCGCGATCGACTGGTGCAAGCGTCATCCGCAGTGGCGGCTGTCGATGCAGACCCACAAATATCTGAACATTCCCT
GAGCCACGGCTTTTGACATC

Downstream 100 bases:

>100_bases
TCCTGCCTGCCCCCGCAGCCCCGCCGTCCGGCGCGGGCTGCCCGTCGCCGCGCACCGTGGCCTCGACTCCCTCCTTCCCG
CGTCGGTAGGGCTTCCCCTG

Product: putative 6-pyruvoyl tetrahydropterin synthase

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVDTEGAPDRGMVMDFADVKALAMEHLVSKWDHAFLVYARD
DVVRSFLEQMADHKTVVIDRIPTVENLAAIAFDLLANVYDAHYGVNLRLERVRLYETPNCWADVERQPGR

Sequences:

>Translated_150_residues
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVDTEGAPDRGMVMDFADVKALAMEHLVSKWDHAFLVYARD
DVVRSFLEQMADHKTVVIDRIPTVENLAAIAFDLLANVYDAHYGVNLRLERVRLYETPNCWADVERQPGR
>Mature_150_residues
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVDTEGAPDRGMVMDFADVKALAMEHLVSKWDHAFLVYARD
DVVRSFLEQMADHKTVVIDRIPTVENLAAIAFDLLANVYDAHYGVNLRLERVRLYETPNCWADVERQPGR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 17325; Mature: 17325

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVDTEGAPDRGMVMDFADVKA
CEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEEEEECCEECCCCCCCCCEEECHHHHHH
LAMEHLVSKWDHAFLVYARDDVVRSFLEQMADHKTVVIDRIPTVENLAAIAFDLLANVYD
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AHYGVNLRLERVRLYETPNCWADVERQPGR
HCCCCCEEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MLITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLRGDLVDTEGAPDRGMVMDFADVKA
CEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEEEEECCEECCCCCCCCCEEECHHHHHH
LAMEHLVSKWDHAFLVYARDDVVRSFLEQMADHKTVVIDRIPTVENLAAIAFDLLANVYD
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AHYGVNLRLERVRLYETPNCWADVERQPGR
HCCCCCEEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]