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The map label for this gene is yahK [H]

Identifier: 116691122

GI number: 116691122

Start: 3417452

End: 3418504

Strand: Direct

Name: yahK [H]

Synonym: Bcen2424_3104

Alternate gene names: 116691122

Gene position: 3417452-3418504 (Clockwise)

Preceding gene: 116691120

Following gene: 116691128

Centisome position: 98.09

GC content: 66.0

Gene sequence:

>1053_bases
ATGAGCACGACCTATGCCTACGCGGCGACCGATTCGCAATCGCCGCTCGCCCCGTTCGAATTCCAGCGTCGCGCGCTGCG
CGACCTCGACGTCCAGATCGACGTCCTCTACTGCGGCGTCTGCCACTCCGATCTTCACCAGGCGCGCAACGAATGGCGCA
ACACGATCTACCCGGTCGTGCCGGGCCATGAAATCGTCGGCCGCGTAACCGCGACCGGCCCGCAGGTGTCGCGCTTCAAG
GTCGGCGAGCTGGTCGGCGTCGGCTGTCTCGTCGATTCGTGCCGCACCTGCGCGAGCTGCGAAGAAGGCCTCGAGCAGTA
TTGCGAGAACGGCTTCGTCGGCACCTACAACGGCCAGGACCGCGTGACGGGCGACATCACGTACGGCGGCTATTCGACGC
AGCTCGTCGTCGACGAGGCGTTCGTGCTGCGCGTGCCGGACACGCTCGACCCGGCCGGCGCCGCGCCGCTGCTGTGCGCG
GGGATCACGACCTACTCGCCGCTGCGGCAGTGGAACGTCGGCCCCGGCAAGAAGGTCGGCATCGTCGGTCTCGGCGGCCT
CGGCCACATGGGTGTGAAGCTGGCGCGCGCGATGGGCGCACACGTCGTGCTGTTCACGACGTCGCCGTCGAAGATCGAGG
ACGGCAAGCGGCTCGGCGCGCATGAAGTGGTGATCTCGAAGGACGAAGCGCAGATGAACGCGCACCTGAACAGCTTCGAC
TTCATCCTGAACACGGTCGCCGCGCAGCACGACCTGAACCCGTTCCTGCACCTGCTCAAGCGCGACGGCACGATGACGCT
CGTCGGCGCGCCGGAGCACGACCATCCGTCGCCGCAGGTGTTCAACCTGATCTTCAAGCGCCGCCGCCTCGCGGGCTCGC
TGATCGGCGGGATCGCGGAAACGCAGGAAATGCTCGACTTCTGCGCGGAGCACGGGATCACGTCCGATATCGAGACGATT
CCGATGCAGCAGATCAACGCCGCCTACGAGCGGATGCTGAAGAGCGACGTGAAGTACCGGTTCGTGGTGGATATGGCGTC
GCTCAAGCAGTAA

Upstream 100 bases:

>100_bases
GGCGGTGCGCTCCTTACGATAGGCACCTGTCTCGCCGCATCGCCACATGATGCGACGGCAGTCTGTTTCGCCGGATCTTT
TCCGGACAAGGAGCCTTTGC

Downstream 100 bases:

>100_bases
GCCGCGCCAAACGAAACGGGCCGCATGTTCGACATGCGGCCCGTTTTGCGTCATCGCGTCATCCGGCTACGCGCCAGGCG
CCACCCAGCGCATCACTTCT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSTTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCASCEEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETI
PMQQINAAYERMLKSDVKYRFVVDMASLKQ

Sequences:

>Translated_350_residues
MSTTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCASCEEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETI
PMQQINAAYERMLKSDVKYRFVVDMASLKQ
>Mature_349_residues
STTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFKV
GELVGVGCLVDSCRTCASCEEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCAG
ITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFDF
ILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETIP
MQQINAAYERMLKSDVKYRFVVDMASLKQ

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI262073058, Length=367, Percent_Identity=23.7057220708447, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI71743840, Length=367, Percent_Identity=23.7057220708447, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4501933, Length=361, Percent_Identity=24.6537396121884, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=24.4565217391304, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4501929, Length=351, Percent_Identity=24.2165242165242, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786518, Length=344, Percent_Identity=63.6627906976744, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI87082401, Length=345, Percent_Identity=35.9420289855072, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=26.3803680981595, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI226510992, Length=315, Percent_Identity=27.9365079365079, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788073, Length=257, Percent_Identity=28.0155642023346, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082125, Length=198, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790045, Length=273, Percent_Identity=27.1062271062271, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=336, Percent_Identity=26.4880952380952, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17562584, Length=339, Percent_Identity=27.4336283185841, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17562582, Length=352, Percent_Identity=27.8409090909091, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25146526, Length=329, Percent_Identity=25.8358662613982, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323980, Length=331, Percent_Identity=38.0664652567976, Blast_Score=189, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6319949, Length=334, Percent_Identity=34.4311377245509, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=34.4615384615385, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=33.2307692307692, Blast_Score=155, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6319621, Length=324, Percent_Identity=31.7901234567901, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323729, Length=324, Percent_Identity=30.5555555555556, Blast_Score=149, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6319258, Length=317, Percent_Identity=26.1829652996845, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=366, Percent_Identity=25.1366120218579, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319257, Length=301, Percent_Identity=23.9202657807309, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17737895, Length=376, Percent_Identity=23.936170212766, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38228; Mature: 38097

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVV
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCASCEEGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RVTGDITYGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCEEEEEEEECEEEEECCCCCCCCCCCCHHHHCCCHHCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGITSDIETIPMQQINAAYERMLKSDVKYRFVVDMASLKQ
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCC
>Mature Secondary Structure 
STTYAYAATDSQSPLAPFEFQRRALRDLDVQIDVLYCGVCHSDLHQARNEWRNTIYPVV
CCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCASCEEGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RVTGDITYGGYSTQLVVDEAFVLRVPDTLDPAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCEEEEEEEECEEEEECCCCCCCCCCCCHHHHCCCHHCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGITSDIETIPMQQINAAYERMLKSDVKYRFVVDMASLKQ
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]