Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 116691000

GI number: 116691000

Start: 3295073

End: 3296890

Strand: Direct

Name: glmS [H]

Synonym: Bcen2424_2982

Alternate gene names: 116691000

Gene position: 3295073-3296890 (Clockwise)

Preceding gene: 116690999

Following gene: 116691001

Centisome position: 94.58

GC content: 67.44

Gene sequence:

>1818_bases
ATGTGCGGCATTGTCGGCGCAGTTGCGCAGCGTAATATCGTTCCGGTGCTGATCGAAGGATTGCGGCGCCTCGAATACCG
TGGCTACGACTCGTGCGGCGTCGCCGTGCTCGAGCCGGGTGCACCGAAGCGCGCGCGCAGCGTCGCGCGCGTCGCCGATC
TCGACACGCAGGTGCGCGAGACGCACCTCGAAGGCACGACGGGCGTCGCGCACACGCGCTGGGCCACCCACGGCGCGCCC
GTCACGCACAACGCGCACCCGATCTTCTCGTCGAACGCGCTCGCGCTCGTGCACAACGGCATCATCGAGAACTTCGAGCC
GCTGCGCGACGCGCTGCGGGCCAAGGGCTACGAATTCGTGTCGCAGACCGACACCGAAGTGATCGCGCACCTCGTGCACA
GCCTGTACCGCGGCAACCTGTTCGACGCGGTGCGCGAAGCCGTGCAGCAGCTGCACGGCGCGTATGCGATCGCCGTGATC
CACAAGGACCAGCCGCACACCGTCGTCGGCGCGCGCCAGGGTTCGCCGCTCGTCGTCGGTCACGGCGACGGCGAGAACTT
CCTCGCGTCCGATGCGCTCGCGCTCGCGGGCAGCACCGACCGCTTCACGTTCCTCGAGGATGGTGACGTATGCGAGCTGT
CGCTCGACGGCGTGACGATCGTCGATCGCCACGGCGCCACCGTGCAGCGCGAAATCCGCGTGGTCAGCGCATACGGCGGC
GCGGTCGAGCTCGGCCCCTATCGCCACTTCATGCAGAAGGAAATCTTCGAGCAGCCGCGCGCGATCGGCGACACCGTGCC
GCAGACGGAAGCCTTCGACGCGACGCTGTTCGGCGACGCCGCGCCCGCCGCGTTCGCGGACATCGACAGCCTGCTGATCC
TCGCGTGCGGCACGAGCTACTACTCGGGCCTCACCGCGAAGTACTGGCTCGAATCGATCGCGAAGATCCCGACCCAGGTC
GAGATCGCCAGCGAATACCGCTATCGCGAGTCGGTGCCGAACCCGCGCCAGCTCGTGCTGGTGATCTCGCAGTCGGGCGA
GACGGCCGATACGCTGGCCGCGCTCAAGCATGCGCAGTCGCTCGGTCACACGCACACGCTCGCGGTCTGCAACGTCGCGA
CGAGCGCGATGGTGCGCCTGACCGAAATGCAGTTCCTGACGCACGCGGGCACCGAGATCGGCGTCGCATCGACGAAGGCG
TTCACGACCCAGCTCGTCGCGCTGTTCGTGCTGGCCGCGACGCTCGGCAAGCTGCGCGGGCACGTCGACGCCGCGCAGGA
AACGCAATTCCTGAAGGAGCTGCGCCACCTGCCGGCCGCGCTGAACAGCGTGCTCGCGCTCGAGCCACAGATCATCGCGT
GGTCGGAGGAATTCGCGCGCAAGGAAAACGCGCTGTTCCTCGGCCGCGGGCTGCATTACCCGATCGCGCTCGAAGGCGCG
TTGAAGCTGAAGGAAATCTCGTACATCCACGCCGAGGCCTATCCGGCCGGCGAACTGAAGCACGGGCCGCTCGCGCTGGT
CACGGAAGCGATGCCGGTCGTCACGGTCGCGCCGAACGACACGCTGCTCGAAAAGCTGAAGTCGAACATGCAGGAAGTGC
GTGCGCGCGGCGGCGAACTGTACGTGTTCGCCGATGCCGACACGCAGATCGTCAACGACGACGGCCTGCACGTGATCCGG
ATGCCGGAGCACTACGGGCAACTGTCGCCGATCCTGCACGTCGTGCCGCTGCAGCTGCTCGCGTATCACACCGCGTGTGC
GCGCGGCACCGACGTCGACAAGCCGCGCAACCTCGCGAAATCGGTGACGGTGGAGTAA

Upstream 100 bases:

>100_bases
GACCGCGAAGAGCGGCTACGTCCGCCCGGTCAAGAAGAAGAGCTGAACCTTTTGCGGGCGCCCACGCGGCGCCCGCTTCG
ACTGACAGGATTGACCATTC

Downstream 100 bases:

>100_bases
TACGCGGCGACGGGAGGGCCCCTCGCCGGGCCCTCCCGACCGCTTGCGGGTGTGAGGCAGGCCGTTTGGCCAGGTCGAAA
TATGTACCACGTAGTGGTAT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDTQVRETHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFEPLRDALRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEDGDVCELSLDGVTIVDRHGATVQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTEAFDATLFGDAAPAAFADIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQETQFLKELRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDTQVRETHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFEPLRDALRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEDGDVCELSLDGVTIVDRHGATVQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTEAFDATLFGDAAPAAFADIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQETQFLKELRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDTQVRETHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFEPLRDALRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEDGDVCELSLDGVTIVDRHGATVQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTEAFDATLFGDAAPAAFADIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQETQFLKELRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=35.4744525547445, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=36.3503649635037, Blast_Score=377, Evalue=1e-104,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=54.9918166939444, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=229, Percent_Identity=28.82096069869, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=719, Percent_Identity=33.7969401947149, Blast_Score=348, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI17532899, Length=429, Percent_Identity=37.995337995338, Blast_Score=276, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17532897, Length=429, Percent_Identity=37.995337995338, Blast_Score=275, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6322745, Length=449, Percent_Identity=36.3028953229399, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323731, Length=433, Percent_Identity=28.8683602771363, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=36.2745098039216, Blast_Score=113, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6323958, Length=172, Percent_Identity=28.4883720930233, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=35.9124087591241, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28573187, Length=256, Percent_Identity=28.515625, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24659598, Length=258, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65565; Mature: 65565

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDTQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
THLEGTTGVAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFEPLRDALRAKGYEFV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVIHKDQPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFLASDALALAGSTDRFTFLEDGDVCELSLDGVTIVDRHGATVQREIRVVSAYGG
CCCCCCHHHHCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCCEEEEEEEEEECCC
AVELGPYRHFMQKEIFEQPRAIGDTVPQTEAFDATLFGDAAPAAFADIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQS
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQETQFLKELRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNDDGLHVIRMPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDTQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
THLEGTTGVAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFEPLRDALRAKGYEFV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVIHKDQPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFLASDALALAGSTDRFTFLEDGDVCELSLDGVTIVDRHGATVQREIRVVSAYGG
CCCCCCHHHHCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCCEEEEEEEEEECCC
AVELGPYRHFMQKEIFEQPRAIGDTVPQTEAFDATLFGDAAPAAFADIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQS
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQETQFLKELRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNDDGLHVIRMPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]