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The map label for this gene is lrhA [H]

Identifier: 116690967

GI number: 116690967

Start: 3261052

End: 3262101

Strand: Reverse

Name: lrhA [H]

Synonym: Bcen2424_2949

Alternate gene names: 116690967

Gene position: 3262101-3261052 (Counterclockwise)

Preceding gene: 116690969

Following gene: 116690966

Centisome position: 93.63

GC content: 74.38

Gene sequence:

>1050_bases
ATGACCGGGCAAGACATTCCGCGCGGCGGCGGCGAGCCGCTCGCGGGGGCCGATGCCACGCTGGCGCGGCCCAACTTCGA
CGTCGCGGCGCTGCGCAGCCTCGTCGCGGGCGTGGATCTTGGCAGTTTCGCGAAGGCGGCCGACCGCGTCGCGCGCTCGT
CGTCGGCGGTGAGCGCGCAGATCCGCAAGCTCGAGGAGCAGGCCGGCACGCCGCTGTTCGTGAAAGCCGGGCGCGGGCTC
GCGCTGACCGACGCCGGCGACGCGATGGTGCGCTACGCGCGGCGGATGATCGAGCTGAACGACGAGGCGGCCGCGGCCGT
GCGCGGCGTGAAGCTCGACGGCTGGGTTCGGGTCGGGCTGCAGGAGGATTTCGGCGAGGCGATCCTGCCGGACGTGCTCG
GGCGGTTCGCGCGCGCCCATCCGAAGGTGAAGATCGAGGCGCGCGTCGCGCGCAACGCCGATCTGCTCGACCGGCTCGAT
GCGAACCAGCTCGATCTGGCGCTCGTGTGGGGCGATCCGGCGTCGGCGGCGCTCGTGTCGCGGGCGGGCATCGACAGCGA
AGCGATCGCGCACGTGCCGATGCAATGGATCGGCGCGGTGGCGGGCGGGCGTGTCGGGATGATGGACGGCGGCGGGGATG
CGGGTGGGGAGGGTGGTGTGCGCGGTGAGGGCGAGGGCGGCCGTGCCGTGCGTGCGACGGACGAGCCGTTGCCGCTCGTC
GTGTTCGACCGGCCGTGCCGGTTCTTCGGCGCGGCGACCGATGCGCTCGACCGTGCGGGCGTGCCGTGGCGCGTCGCGTT
CACGACGCCGAGCCTGGCCGGCTTATGGGCGGCCGCGGCGGCCGGTCTCGGGCTGACGGTGCGCTCGCATTACGGGCTGC
CCGCGTCGGTGCGCGTGCTCGATGCGGCGTCGTGCGGGCTGCCGGCGCTGCCGAGCCTGCCGCTGATCCTGCTGCGGCGC
ACGTCGTCGGCGACGCCGACGGTCGACCGACTCGCGCGGATCGTGACGCAGGCGGTGGGGGAAGCGACGGAGGGAGTGCT
TGCGGCGTGA

Upstream 100 bases:

>100_bases
AGGCCCGGTTCGAAGTTGACGTCCACAGTCTGGCGGCCTACATTCATCCTGAAAATCGGAAAGTTTTTGACGAATCGTTC
GATGAAACAGGATGATTGAA

Downstream 100 bases:

>100_bases
TTCCGGACGCGACGACCAGCCAGTGTCCGAGCGGCTGGACGTTCGGCCTATTGGAGCAATGACGCGAATGTCGTAACAAT
GGTGGGTCACTCAATGGAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTGQDIPRGGGEPLAGADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQIRKLEEQAGTPLFVKAGRGL
ALTDAGDAMVRYARRMIELNDEAAAAVRGVKLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVKIEARVARNADLLDRLD
ANQLDLALVWGDPASAALVSRAGIDSEAIAHVPMQWIGAVAGGRVGMMDGGGDAGGEGGVRGEGEGGRAVRATDEPLPLV
VFDRPCRFFGAATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAASCGLPALPSLPLILLRR
TSSATPTVDRLARIVTQAVGEATEGVLAA

Sequences:

>Translated_349_residues
MTGQDIPRGGGEPLAGADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQIRKLEEQAGTPLFVKAGRGL
ALTDAGDAMVRYARRMIELNDEAAAAVRGVKLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVKIEARVARNADLLDRLD
ANQLDLALVWGDPASAALVSRAGIDSEAIAHVPMQWIGAVAGGRVGMMDGGGDAGGEGGVRGEGEGGRAVRATDEPLPLV
VFDRPCRFFGAATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAASCGLPALPSLPLILLRR
TSSATPTVDRLARIVTQAVGEATEGVLAA
>Mature_348_residues
TGQDIPRGGGEPLAGADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQIRKLEEQAGTPLFVKAGRGLA
LTDAGDAMVRYARRMIELNDEAAAAVRGVKLDGWVRVGLQEDFGEAILPDVLGRFARAHPKVKIEARVARNADLLDRLDA
NQLDLALVWGDPASAALVSRAGIDSEAIAHVPMQWIGAVAGGRVGMMDGGGDAGGEGGVRGEGEGGRAVRATDEPLPLVV
FDRPCRFFGAATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVLDAASCGLPALPSLPLILLRRT
SSATPTVDRLARIVTQAVGEATEGVLAA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=316, Percent_Identity=31.6455696202532, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787806, Length=144, Percent_Identity=28.4722222222222, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790399, Length=172, Percent_Identity=30.2325581395349, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994962, Length=146, Percent_Identity=29.4520547945205, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787601, Length=144, Percent_Identity=26.3888888888889, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=186, Percent_Identity=26.3440860215054, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790208, Length=152, Percent_Identity=27.6315789473684, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35974; Mature: 35843

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQDIPRGGGEPLAGADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IRKLEEQAGTPLFVKAGRGLALTDAGDAMVRYARRMIELNDEAAAAVRGVKLDGWVRVGL
HHHHHHHCCCEEEEECCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHCEEECCEEEECC
QEDFGEAILPDVLGRFARAHPKVKIEARVARNADLLDRLDANQLDLALVWGDPASAALVS
HHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCEEEEEEECCCHHHHHHH
RAGIDSEAIAHVPMQWIGAVAGGRVGMMDGGGDAGGEGGVRGEGEGGRAVRATDEPLPLV
HCCCCHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEE
VFDRPCRFFGAATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVL
EECCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEE
DAASCGLPALPSLPLILLRRTSSATPTVDRLARIVTQAVGEATEGVLAA
ECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TGQDIPRGGGEPLAGADATLARPNFDVAALRSLVAGVDLGSFAKAADRVARSSSAVSAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IRKLEEQAGTPLFVKAGRGLALTDAGDAMVRYARRMIELNDEAAAAVRGVKLDGWVRVGL
HHHHHHHCCCEEEEECCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHCEEECCEEEECC
QEDFGEAILPDVLGRFARAHPKVKIEARVARNADLLDRLDANQLDLALVWGDPASAALVS
HHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCEEEEEEECCCHHHHHHH
RAGIDSEAIAHVPMQWIGAVAGGRVGMMDGGGDAGGEGGVRGEGEGGRAVRATDEPLPLV
HCCCCHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEE
VFDRPCRFFGAATDALDRAGVPWRVAFTTPSLAGLWAAAAAGLGLTVRSHYGLPASVRVL
EECCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEE
DAASCGLPALPSLPLILLRRTSSATPTVDRLARIVTQAVGEATEGVLAA
ECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]