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The map label for this gene is dppA [H]

Identifier: 116690941

GI number: 116690941

Start: 3229475

End: 3231079

Strand: Direct

Name: dppA [H]

Synonym: Bcen2424_2923

Alternate gene names: 116690941

Gene position: 3229475-3231079 (Clockwise)

Preceding gene: 116690940

Following gene: 116690942

Centisome position: 92.7

GC content: 65.17

Gene sequence:

>1605_bases
ATGCACGTCAAGCTGTTCGCCGCGGCCGCCGTGGCCACGGCCCTCGCCGCCCTTGCCGCCCCCGGCCTCGCCGCCGCCAA
GCCGCTCACCGTCTGCACGGAATCGAGCCCGGACGGCTTCGACGTCGTGCAGTACAACTCGCTCGTCACGACCAACGCAT
CGGCCGACGTGGTCTTCAACACACTCGTGTCCTACGACGAAGCCGCGAAGAAGGTCGTGCCCGCGCTCGCGGACAAATGG
GAAGCGAGCGCCGACGGCCTCACGTACACGTTCCACCTGCGCCCGAACGTCGCATTCCAGACCACCGACTACTTCAAGCC
GGGCCGCACGCTGAACGCGGACGACGTCGTGTTCACGTTCACGCGGATGCTCGACGATGCGAATCCGTGGCACAAGGTCG
CCGGCGCGAGCGGCTTTCCGCACGCGCAGTCGATGGGTCTCGTGAAGCTCGTGAAATCGGTCACGAAGGTCGACGACAGC
ACCGTGAAGTTCGTGCTGAACGAACCGAACGCGACGTTCGTGCCGATCCTGACGATGGGCTTCGCGTCGATCTACTCGGC
CGAATACGCGGACCAACTGCTGAAGGCCGGCAAGCAGGCCGACCTGAACGCGAAGCCGGTCGGCACCGGCCCGTTCGTGC
TGAAGAGCTACACGAAGGACGCGCTAATCCGCTACGACGCGAATCCGACGTACTGGGGCACGAAGCCGAAGGTCGACCGG
CTGATCTACGCGATCACGCCCGACCCGTCAGTGCGCCTGCAGAAGGTGAAGGCCGGCGAATGCCAGATCGCGCTGTCGCC
GAAGCCGCAGGACGTGCTCGCCGCGAAAGGCGAAAGCGCGCTGAAGGTCGTGCAGACGCCCGCGTTCATGACTGCGTTCG
TCGCGCTGAACACGCAGAAGAAGCCGCTCGACAGCGACAAGGTGCGCGAGGCGCTGAACCTCGCGTTCGACCGCGCGACC
TACCTGAAGGTCGTGTTCGACAACACCGCGACGGCCGCGAACAACCCGTATCCGCCGAACACGTGGAGCTATGCGAAGGA
CGTCGCGCCGTATGCGTACGATCCCGCGAAGGCGAAGCAACTGCTCGCGCAGGCAGGCTTCCCGAACGGCTTCTCGACCA
CCATCTGGACGCGCCCGACCGGCAGCGTACTGAACCCGAACCCGAAGGTCGGCGCGGAACTGCTGCAGGCCGACCTCGCG
AAGATCGGCGTGAAGGCCGAAGTGAAGGTGATCGAATGGGGCGAGCTGATCAAGCAGGCGAAGCTCGGCCAGCATGACAT
GCTGTTCATGGGCTGGGCCGGCGACAACGGCGATCCGGACAACTATCTGTCGCCGCTGTTCAGCTGCAACGCGGTGAAGT
CGGGCATCAACTTCGCGCGCTTCTGCGATGCGCAGCTCGACAAGCTGATCGCCGACGGCAAGTCGACCGCCGACCAGGCC
AAGCGCGCGAAGCTGTACGAAAGCGCGCAGAAGATCATCCACGACCAGGCGCTGTGGATCCCGCTCGGCTACCCGACCGC
GGCCGCGTTGACGCGCACGAACGTGAGCGGCTATCACGTGAGTCCGTTCGGACGACAGAACTTCACGGCGGTCGCCGTGC
AGTAA

Upstream 100 bases:

>100_bases
TTGACGGTATGCTATTCGCCAGCCGCGTCGGCCCTGCCCGCTTCCGGGCCGCGCCAGCCTCCGTCATTCAGCGAAAAACA
CACGCCACGTGGGAGATCCT

Downstream 100 bases:

>100_bases
CCGTGCGTGGCGCGCAAGCGACGGCGTGCACGCCGCTCGCTTGCGGCCCGCGCGCCGCGCTTGCTACACTGCGCGCCTGT
TCCTCCTACCGGACGCCAGC

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MHVKLFAAAAVATALAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVVFNTLVSYDEAAKKVVPALADKW
EASADGLTYTFHLRPNVAFQTTDYFKPGRTLNADDVVFTFTRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDS
TVKFVLNEPNATFVPILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDR
LIYAITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDSDKVREALNLAFDRAT
YLKVVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLA
KIGVKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKSTADQA
KRAKLYESAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTAVAVQ

Sequences:

>Translated_534_residues
MHVKLFAAAAVATALAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVVFNTLVSYDEAAKKVVPALADKW
EASADGLTYTFHLRPNVAFQTTDYFKPGRTLNADDVVFTFTRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDS
TVKFVLNEPNATFVPILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDR
LIYAITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDSDKVREALNLAFDRAT
YLKVVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLA
KIGVKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKSTADQA
KRAKLYESAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTAVAVQ
>Mature_534_residues
MHVKLFAAAAVATALAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVVFNTLVSYDEAAKKVVPALADKW
EASADGLTYTFHLRPNVAFQTTDYFKPGRTLNADDVVFTFTRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDS
TVKFVLNEPNATFVPILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDR
LIYAITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDSDKVREALNLAFDRAT
YLKVVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLA
KIGVKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKSTADQA
KRAKLYESAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTAVAVQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=44.0839694656489, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1787551, Length=502, Percent_Identity=34.8605577689243, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1787052, Length=530, Percent_Identity=31.6981132075472, Blast_Score=225, Evalue=7e-60,
Organism=Escherichia coli, GI1787762, Length=482, Percent_Identity=25.3112033195021, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1789887, Length=559, Percent_Identity=25.5813953488372, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787495, Length=534, Percent_Identity=24.3445692883895, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI87081878, Length=526, Percent_Identity=24.9049429657795, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1789397, Length=492, Percent_Identity=25.609756097561, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57641; Mature: 57641

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVKLFAAAAVATALAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVVFN
CEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHH
TLVSYDEAAKKVVPALADKWEASADGLTYTFHLRPNVAFQTTDYFKPGRTLNADDVVFTF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHH
TRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDSTVKFVLNEPNATFVPILTMG
HHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHH
FASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCE
LIYAITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQK
EEEEECCCCCCEEEEEECCCEEEEECCCCHHHHHCCCCCHHHHHCCCHHHHHHHEECCCC
KPLDSDKVREALNLAFDRATYLKVVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQ
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHH
LLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLAKIGVKAEVKVIEWGELIKQA
HHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
KLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKSTADQA
HCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHH
KRAKLYESAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTAVAVQ
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHEECCCCCEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MHVKLFAAAAVATALAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVVFN
CEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHH
TLVSYDEAAKKVVPALADKWEASADGLTYTFHLRPNVAFQTTDYFKPGRTLNADDVVFTF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHH
TRMLDDANPWHKVAGASGFPHAQSMGLVKLVKSVTKVDDSTVKFVLNEPNATFVPILTMG
HHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHH
FASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCE
LIYAITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQK
EEEEECCCCCCEEEEEECCCEEEEECCCCHHHHHCCCCCHHHHHCCCHHHHHHHEECCCC
KPLDSDKVREALNLAFDRATYLKVVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQ
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHH
LLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLAKIGVKAEVKVIEWGELIKQA
HHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
KLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDAQLDKLIADGKSTADQA
HCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHH
KRAKLYESAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTAVAVQ
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHEECCCCCEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]