Definition Burkholderia cenocepacia HI2424 chromosome 1, complete sequence.
Accession NC_008542
Length 3,483,902

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The map label for this gene is ucpA [C]

Identifier: 116690940

GI number: 116690940

Start: 3228263

End: 3229036

Strand: Direct

Name: ucpA [C]

Synonym: Bcen2424_2922

Alternate gene names: 116690940

Gene position: 3228263-3229036 (Clockwise)

Preceding gene: 116690939

Following gene: 116690941

Centisome position: 92.66

GC content: 70.93

Gene sequence:

>774_bases
ATGACTACTCCGCTGAAGGTCTTCATCACCGGCGCGTCGAGCGGCCTCGGCCTTGCGATGGCCGAGGAATACGCCCGTCA
GGGCGCCACGCTCGCCCTCGTCGCGCGACGCACCGATGCACTCGATGCGTTCGCGCGGCGGTTCCCGAAGCTGTCCATCT
CCGTCTATTCCGCCGACGTGCGCGACGCCGATGCGCTCGCGACGGCCGCCGCGTCGTTCATCGCCGCGCACGGCTGCCCC
GACGTCGTGATCGCGAACGCGGGTATCAGCCAGGGCGCCGTCACGGGCCAGGGCGACCTCGCGGCGTTCCGCGACGTAAT
GGACATCAACTACTACGGGATGGTCGCGACGTTCGAGCCGTTCGTCGGCCCGATGACGGCCGCGCGCCACGGCACGCTGG
TCGGCGTCGCGAGCGTCGCCGGCGTGCGCGGCCTGCCCGGCTCCGGTGCGTACAGCGCGTCGAAATCGGCCGCGATCAAG
TATCTGGAAGCGCTGCGCGTCGAGCTGCGCCCGGCCGGCGTCGGCGTCGTGACGATCGCGCCCGGCTACATCCGCACGCC
GATGACCGCGCACAACCCGTACCGGATGCCGTTCCTGATGGACGCCGATCGCTTCGCCGCGCGCGCGGCGCGCGCGATCG
CCCGGCAGCACGCGTTCCGCGTGATTCCGTGGCAGATGGGTGTCGTCGCGAAGGTGCTGCACGTGCTGCCGCGCTGGCTG
TACGACCGCTTGTTCGAAAAGGCGCCGCGCAAGCCGAAGGCCGGCGCGCACTGA

Upstream 100 bases:

>100_bases
CCGGCTTACACGAACAGCATCCCGGGTACCGCGCAGGTGCTCGACTTCCTCGTGAAGCAGGTTCAGGACAAGAAGCTCTG
ATCCCCGCCCGCGCGCCGGC

Downstream 100 bases:

>100_bases
GCGCGTCGTGGATCCCGGCGCGCGTCTCGCCGGATCGCTGTCGGGCCTCGGCCTGATCCGCATCGCCATCCCGCGAAACC
GCGCGGGTTTCTCCCCCTCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTTPLKVFITGASSGLGLAMAEEYARQGATLALVARRTDALDAFARRFPKLSISVYSADVRDADALATAAASFIAAHGCP
DVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEPFVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIK
YLEALRVELRPAGVGVVTIAPGYIRTPMTAHNPYRMPFLMDADRFAARAARAIARQHAFRVIPWQMGVVAKVLHVLPRWL
YDRLFEKAPRKPKAGAH

Sequences:

>Translated_257_residues
MTTPLKVFITGASSGLGLAMAEEYARQGATLALVARRTDALDAFARRFPKLSISVYSADVRDADALATAAASFIAAHGCP
DVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEPFVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIK
YLEALRVELRPAGVGVVTIAPGYIRTPMTAHNPYRMPFLMDADRFAARAARAIARQHAFRVIPWQMGVVAKVLHVLPRWL
YDRLFEKAPRKPKAGAH
>Mature_256_residues
TTPLKVFITGASSGLGLAMAEEYARQGATLALVARRTDALDAFARRFPKLSISVYSADVRDADALATAAASFIAAHGCPD
VVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEPFVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIKY
LEALRVELRPAGVGVVTIAPGYIRTPMTAHNPYRMPFLMDADRFAARAARAIARQHAFRVIPWQMGVVAKVLHVLPRWLY
DRLFEKAPRKPKAGAH

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=31.6062176165803, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=29.5918367346939, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=28.7958115183246, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40807363, Length=231, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4503817, Length=199, Percent_Identity=32.1608040201005, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI4758504, Length=244, Percent_Identity=30.7377049180328, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI142976729, Length=260, Percent_Identity=26.5384615384615, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31543615, Length=226, Percent_Identity=23.8938053097345, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI223718074, Length=191, Percent_Identity=32.9842931937173, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=218, Percent_Identity=31.1926605504587, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786701, Length=186, Percent_Identity=31.7204301075269, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=25.1396648044693, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=232, Percent_Identity=28.8793103448276, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17508895, Length=243, Percent_Identity=27.1604938271605, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17570069, Length=186, Percent_Identity=31.7204301075269, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=186, Percent_Identity=30.1075268817204, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17507613, Length=191, Percent_Identity=31.413612565445, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=191, Percent_Identity=31.413612565445, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=203, Percent_Identity=30.0492610837438, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=241, Percent_Identity=26.9709543568465, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=188, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=188, Percent_Identity=28.7234042553192, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=188, Percent_Identity=25, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=229, Percent_Identity=28.82096069869, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=194, Percent_Identity=26.2886597938144, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=31.413612565445, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=221, Percent_Identity=33.0316742081448, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=31.3829787234043, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644339, Length=208, Percent_Identity=31.7307692307692, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24649181, Length=264, Percent_Identity=25.7575757575758, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28571526, Length=185, Percent_Identity=29.7297297297297, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281364892, Length=216, Percent_Identity=27.3148148148148, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355631, Length=204, Percent_Identity=28.921568627451, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24580925, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640442, Length=189, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=29.3650793650794, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581726, Length=202, Percent_Identity=25.2475247524752, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356301, Length=188, Percent_Identity=29.2553191489362, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644337, Length=185, Percent_Identity=32.4324324324324, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355319, Length=185, Percent_Identity=25.9459459459459, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27258; Mature: 27127

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTTPLKVFITGASSGLGLAMAEEYARQGATLALVARRTDALDAFARRFPKLSISVYSADV
CCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCEEEEEEECCC
RDADALATAAASFIAAHGCPDVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEP
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCC
FVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIKYLEALRVELRPAGVGVVTIA
HHCCHHHHCCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCEEEEEEC
PGYIRTPMTAHNPYRMPFLMDADRFAARAARAIARQHAFRVIPWQMGVVAKVLHVLPRWL
CCHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHH
YDRLFEKAPRKPKAGAH
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTPLKVFITGASSGLGLAMAEEYARQGATLALVARRTDALDAFARRFPKLSISVYSADV
CCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCEEEEEEECCC
RDADALATAAASFIAAHGCPDVVIANAGISQGAVTGQGDLAAFRDVMDINYYGMVATFEP
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCC
FVGPMTAARHGTLVGVASVAGVRGLPGSGAYSASKSAAIKYLEALRVELRPAGVGVVTIA
HHCCHHHHCCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCEEEEEEC
PGYIRTPMTAHNPYRMPFLMDADRFAARAARAIARQHAFRVIPWQMGVVAKVLHVLPRWL
CCHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHH
YDRLFEKAPRKPKAGAH
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]