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The map label for this gene is ggt [H]

Identifier: 116690900

GI number: 116690900

Start: 3184347

End: 3186221

Strand: Direct

Name: ggt [H]

Synonym: Bcen2424_2882

Alternate gene names: 116690900

Gene position: 3184347-3186221 (Clockwise)

Preceding gene: 116690899

Following gene: 116690901

Centisome position: 91.4

GC content: 70.99

Gene sequence:

>1875_bases
ATGTTCGACCGGATTCGTCCGCATTCGCGTCCCTGGACGCTGCTCGCCGCCGTCGCGTTCGTCGCGTTGAACGCCGGCTG
CACGTCCCCGTCCGCGCCGTCGGGCGCCGTCGTCCCGGTCGCCGCCGCGTCGGGCGCGGCCGTCCCGCTGCCCGGCGTTC
ACGCGCCCGAACTGTCGTCCGGCTGGACCGACAAGTCGGGCTGGACCTCGCAGCACTTCATGATCGCGGCCGCGAACCCG
CTCGCGACGCAAGCCGGCTACGACATGCTGAAGGCGGGCGGCACCGCGATCGATGCGGCCATCGCGACGCAGATGGTGCT
CGCGCTGGTCGAGCCGCAATCGTCAGGGATCGGCGGCGGCGCGTTCATGCTGTACTTCGACGGCAAGACGACGCAGGCGT
ACGACGGCCGCGAAACCGCGCCGGCCGCCGCGACCGAGCGCCTCTTCTACGGGCCGACCGGCCAGCCGATGAGCTTCTAC
GAAGGTGTCGTCGGCGGGCGCTCGGTCGGCACGCCGGGCGTGCTGCGCATGCTCGACGCCGCGCACCGCGCGCACGGCAA
GCTGCCGTGGCGCCGGTTGTTCCAGCCGGCCATCCGGCTCGCCGAGCGCGGCTTCACGATCAGCCCGCGCCTGGCGATGC
TGATCGCGAACGACAAGTACCTGAAGAACGACCCGGCCGCCCGCGCGTACTTCTACAACGCGGACGGCACGCCGAAGGCC
GCCGGCACGGTGCTGAAGAACCCGGCGCTCGCGACCGTGCTGCGCCAGGTCGCCGACCGTGGCGCGAACGCGTTCTACAG
CGGCGCGATCGCGCGCGACATCGTGACGAAGGTGCGCAAGCACCCGACCAACCCGGGGCTGCTGTCGCTGCAGGATCTCG
CGCGCTACAAGGCGAAGGTGCGCGCGCCGCTGTGCGCCGACTACCGGCGCTCGGTCGTGTGCGGGATGCCGCCGCCGTCG
TCGGGCGGCCTCGCGATCGCGCAGATGCTCGGCATCCTCGAAGCGATGCCCGACTGGCAGCAGATCGGTGCGCAGAAACC
GGTGCGCAACGAGGTCGGCTACGAGCCGACGCCGTTCGCCGCGCACCTGTTCAGCGAAGCCGGGCGCCTCGCGTACGCGG
ACCGTGCGCGCTACGTGGCCGATCCCGATTTCGTGCCGCTGCCGGGCGGCACCTGGGCGAGCCTCACCGACAAGACCTAT
CTCGCGCAGCGCGCGCGGCTGATCGGCGACACCAGCATGGGCGTCGCGCAAGCCGGCACGCCGCAGGGCGCGGCGCTCGC
GCTGGCCGACGACCGCAGCCCCGAATTGCCGTCGACCTCCGACATCGCGATCGTCGACCGCTACGGCCAGGCGCTGTCGA
TGACGACCAGCATCGAGGACGCGTTCGGCTCCCGGCTGATGGTGCGCGGCTTCATGCTGAACAACCAGCTCACCGATTTC
TCGTTCGCGTCGAACGACGACGGCCGGCCGATCGCGAACCGCGTGCAGCCGGGCAAGCGACCGCGCTCGGCGATGTCGCC
GGAACTGGTGTTCGACAAGAAGACGAAGCAGGTGACGATGATCGTCGGTTCGGCCGGCGGCCCCGCGATCATCAATCACG
TGACGAAGACGCTGGTCGGCGTGCTCGACTGGGGCATGACGATGCAGCAGGCGATCGCGCTGCCGAACTTCGGGTCGATG
AACGGGCCGACGCAGCTCGAACGCGGCCGCGTGTCGGACGCGCTCGCCGACGGGCTGAAGGGCCGCGGGCACGACGTGCA
GATCGTCGAGATGAACTCGGGGCTGCAGGGCATCCAGCGGCTGAACGTGCAGGGGCAGACGGTGTGGTTCGGCGGCGCGG
ACCCGCGCCGGGAAGGGGTCGCGATGGGCGATTGA

Upstream 100 bases:

>100_bases
GCGCCGGGGCGGGCCGCACCGTTGCGCCCGCACCGACGTAAACGTCAACGTCAACATCAACGCCGCCGTCTCCTTCGAAT
TCACTGCTGCCGAGGGTTCA

Downstream 100 bases:

>100_bases
GCGGACGATGTTCGTCCGTCGGTGGCGGTGTGCGTGAAGCGGCGCGCACCGCCCATGAGGCTCTGGCATTCATGCGCCAT
GCGCCCCCGCCCTCTCCGCG

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MFDRIRPHSRPWTLLAAVAFVALNAGCTSPSAPSGAVVPVAAASGAAVPLPGVHAPELSSGWTDKSGWTSQHFMIAAANP
LATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDGRETAPAAATERLFYGPTGQPMSFY
EGVVGGRSVGTPGVLRMLDAAHRAHGKLPWRRLFQPAIRLAERGFTISPRLAMLIANDKYLKNDPAARAYFYNADGTPKA
AGTVLKNPALATVLRQVADRGANAFYSGAIARDIVTKVRKHPTNPGLLSLQDLARYKAKVRAPLCADYRRSVVCGMPPPS
SGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFAAHLFSEAGRLAYADRARYVADPDFVPLPGGTWASLTDKTY
LAQRARLIGDTSMGVAQAGTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSIEDAFGSRLMVRGFMLNNQLTDF
SFASNDDGRPIANRVQPGKRPRSAMSPELVFDKKTKQVTMIVGSAGGPAIINHVTKTLVGVLDWGMTMQQAIALPNFGSM
NGPTQLERGRVSDALADGLKGRGHDVQIVEMNSGLQGIQRLNVQGQTVWFGGADPRREGVAMGD

Sequences:

>Translated_624_residues
MFDRIRPHSRPWTLLAAVAFVALNAGCTSPSAPSGAVVPVAAASGAAVPLPGVHAPELSSGWTDKSGWTSQHFMIAAANP
LATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDGRETAPAAATERLFYGPTGQPMSFY
EGVVGGRSVGTPGVLRMLDAAHRAHGKLPWRRLFQPAIRLAERGFTISPRLAMLIANDKYLKNDPAARAYFYNADGTPKA
AGTVLKNPALATVLRQVADRGANAFYSGAIARDIVTKVRKHPTNPGLLSLQDLARYKAKVRAPLCADYRRSVVCGMPPPS
SGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFAAHLFSEAGRLAYADRARYVADPDFVPLPGGTWASLTDKTY
LAQRARLIGDTSMGVAQAGTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSIEDAFGSRLMVRGFMLNNQLTDF
SFASNDDGRPIANRVQPGKRPRSAMSPELVFDKKTKQVTMIVGSAGGPAIINHVTKTLVGVLDWGMTMQQAIALPNFGSM
NGPTQLERGRVSDALADGLKGRGHDVQIVEMNSGLQGIQRLNVQGQTVWFGGADPRREGVAMGD
>Mature_624_residues
MFDRIRPHSRPWTLLAAVAFVALNAGCTSPSAPSGAVVPVAAASGAAVPLPGVHAPELSSGWTDKSGWTSQHFMIAAANP
LATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDGRETAPAAATERLFYGPTGQPMSFY
EGVVGGRSVGTPGVLRMLDAAHRAHGKLPWRRLFQPAIRLAERGFTISPRLAMLIANDKYLKNDPAARAYFYNADGTPKA
AGTVLKNPALATVLRQVADRGANAFYSGAIARDIVTKVRKHPTNPGLLSLQDLARYKAKVRAPLCADYRRSVVCGMPPPS
SGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFAAHLFSEAGRLAYADRARYVADPDFVPLPGGTWASLTDKTY
LAQRARLIGDTSMGVAQAGTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSIEDAFGSRLMVRGFMLNNQLTDF
SFASNDDGRPIANRVQPGKRPRSAMSPELVFDKKTKQVTMIVGSAGGPAIINHVTKTLVGVLDWGMTMQQAIALPNFGSM
NGPTQLERGRVSDALADGLKGRGHDVQIVEMNSGLQGIQRLNVQGQTVWFGGADPRREGVAMGD

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=557, Percent_Identity=30.5206463195691, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI73915090, Length=557, Percent_Identity=30.5206463195691, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI73915096, Length=557, Percent_Identity=30.5206463195691, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI73915094, Length=557, Percent_Identity=30.5206463195691, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI113429324, Length=556, Percent_Identity=29.3165467625899, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI113429326, Length=561, Percent_Identity=28.8770053475936, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI153266885, Length=568, Percent_Identity=27.9929577464789, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI153266901, Length=569, Percent_Identity=27.9437609841828, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI109148539, Length=533, Percent_Identity=27.5797373358349, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI153266907, Length=566, Percent_Identity=26.8551236749117, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI30581157, Length=194, Percent_Identity=31.4432989690722, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI30581155, Length=194, Percent_Identity=31.4432989690722, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI171543825, Length=178, Percent_Identity=31.4606741573034, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1789856, Length=559, Percent_Identity=34.7048300536673, Blast_Score=265, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI212646519, Length=582, Percent_Identity=30.7560137457045, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI72000294, Length=582, Percent_Identity=30.7560137457045, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI193208247, Length=532, Percent_Identity=31.7669172932331, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI193208245, Length=532, Percent_Identity=31.7669172932331, Blast_Score=211, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI17542894, Length=547, Percent_Identity=30.3473491773309, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17506189, Length=562, Percent_Identity=27.7580071174377, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI72001497, Length=236, Percent_Identity=27.5423728813559, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72001495, Length=236, Percent_Identity=27.5423728813559, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323330, Length=232, Percent_Identity=30.6034482758621, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859893, Length=557, Percent_Identity=30.1615798922801, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24642670, Length=563, Percent_Identity=30.0177619893428, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24642666, Length=563, Percent_Identity=30.0177619893428, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI45551474, Length=563, Percent_Identity=30.0177619893428, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161077880, Length=562, Percent_Identity=29.7153024911032, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161077878, Length=562, Percent_Identity=29.7153024911032, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161077496, Length=531, Percent_Identity=26.7419962335217, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI18859741, Length=573, Percent_Identity=26.5270506108202, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 66174; Mature: 66174

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRIRPHSRPWTLLAAVAFVALNAGCTSPSAPSGAVVPVAAASGAAVPLPGVHAPELSS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
GWTDKSGWTSQHFMIAAANPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGG
CCCCCCCCCCCEEEEEECCCHHHHHCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
AFMLYFDGKTTQAYDGRETAPAAATERLFYGPTGQPMSFYEGVVGGRSVGTPGVLRMLDA
EEEEEECCCCCCCCCCCCCCCHHHHCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHH
AHRAHGKLPWRRLFQPAIRLAERGFTISPRLAMLIANDKYLKNDPAARAYFYNADGTPKA
HHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCCCEEEEECCCCCCHH
AGTVLKNPALATVLRQVADRGANAFYSGAIARDIVTKVRKHPTNPGLLSLQDLARYKAKV
CCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
RAPLCADYRRSVVCGMPPPSSGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFA
CCCHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHCCCCCCCHH
AHLFSEAGRLAYADRARYVADPDFVPLPGGTWASLTDKTYLAQRARLIGDTSMGVAQAGT
HHHHHHCCCEEEHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSIEDAFGSRLMVRGFMLNNQLTDF
CCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHCCCEEEEEEEECCCCCCC
SFASNDDGRPIANRVQPGKRPRSAMSPELVFDKKTKQVTMIVGSAGGPAIINHVTKTLVG
CCCCCCCCCCHHHHCCCCCCCCHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHH
VLDWGMTMQQAIALPNFGSMNGPTQLERGRVSDALADGLKGRGHDVQIVEMNSGLQGIQR
HHHHCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
LNVQGQTVWFGGADPRREGVAMGD
HCCCCCEEEECCCCCHHCCCCCCC
>Mature Secondary Structure
MFDRIRPHSRPWTLLAAVAFVALNAGCTSPSAPSGAVVPVAAASGAAVPLPGVHAPELSS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
GWTDKSGWTSQHFMIAAANPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGG
CCCCCCCCCCCEEEEEECCCHHHHHCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
AFMLYFDGKTTQAYDGRETAPAAATERLFYGPTGQPMSFYEGVVGGRSVGTPGVLRMLDA
EEEEEECCCCCCCCCCCCCCCHHHHCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHH
AHRAHGKLPWRRLFQPAIRLAERGFTISPRLAMLIANDKYLKNDPAARAYFYNADGTPKA
HHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCCCEEEEECCCCCCHH
AGTVLKNPALATVLRQVADRGANAFYSGAIARDIVTKVRKHPTNPGLLSLQDLARYKAKV
CCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
RAPLCADYRRSVVCGMPPPSSGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFA
CCCHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHCCCCCCCHH
AHLFSEAGRLAYADRARYVADPDFVPLPGGTWASLTDKTYLAQRARLIGDTSMGVAQAGT
HHHHHHCCCEEEHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSIEDAFGSRLMVRGFMLNNQLTDF
CCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHCCCEEEEEEEECCCCCCC
SFASNDDGRPIANRVQPGKRPRSAMSPELVFDKKTKQVTMIVGSAGGPAIINHVTKTLVG
CCCCCCCCCCHHHHCCCCCCCCHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHH
VLDWGMTMQQAIALPNFGSMNGPTQLERGRVSDALADGLKGRGHDVQIVEMNSGLQGIQR
HHHHCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
LNVQGQTVWFGGADPRREGVAMGD
HCCCCCEEEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA