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The map label for this gene is yadA [H]

Identifier: 116690901

GI number: 116690901

Start: 3186622

End: 3188415

Strand: Direct

Name: yadA [H]

Synonym: Bcen2424_2883

Alternate gene names: 116690901

Gene position: 3186622-3188415 (Clockwise)

Preceding gene: 116690900

Following gene: 116690908

Centisome position: 91.47

GC content: 69.96

Gene sequence:

>1794_bases
ATGTCAGGTATCTCCGCTGCACACTCCCGTACGACGCGTGCCCGCTCGCATGCTTCGCTCAAACGACAACGCACGCCGTC
CGCCCGCCTGTCGGCGCTCGCCCTCGCCATCGCCGCACTCGCGCCGTGCTACGGCCACGCGTCCGGCACCGATCTCGTCG
AGACCAACCTGATCGTCAAGGGCGGCGACAGCGGCGACCCGATCGCCTCGGGCGCCGGCTCGATCGCAATCGGTGCGGGC
GCGAAGGCGACCGGCGAAACCGGTGGCGATTATTCCGCGATCGCGATCGGTGACAGAGCCGTCGCCAATGGTCGCTCGAC
CATCGCCGTCGGCGAAGCGGCGAACGTCCATGGCGATCGCTCGAGCGCCTTCGGCGTGTCGTCAAGCGTCAACGCGAATC
GCGCGCTGGCGCTCGGCGCGGACGCGAAGGTCACCGCGCACGGTGCGGTCGCGCTCGGCCAGGGCAGCGTCGCCGATCGC
ACGAACACCGTGTCGATCGGCACGGCGGACACCCAGCGCCAGCTCGTCAACCTCGGCGCAGGCACGCGCGACACCGACGC
AACCAACCTGTCGCAGTTGAAGCCCGTGGTCGCGGCGCTCGGCGGCGATGCGGCCGTCAACGCGGACGGCACCGTGCGCG
GCCCGAACTACACGGTGGACGGACGATCGTTCAACACCGTCGGCGGTGCGCTGACCCAACTCGACGGACGCGTCACGACG
ATCGACGGGCGTGTCACCACCGTCGAAAACAACGTCACGTCGATCCGCAACGACGTCACCGATCTCGGCACGCGGCTCGA
CAACGGCACGACCGGCCTCGTCCGGCAGGACCCGGCGAATCTCGCAATCTCGATCGGCGCCGACAAGGGCGGCACGTCGG
TCAGCGTCGCCGGCACTGACGGCACGCGCACGCTGACCGGCCTGTCGAACGGCACCGGCGACACCGATGCCGTGACGGTC
GCGCAGCTCAAGGCGACCGGGCTGATCGATCCGAACGGCAAGGCGCTCGGCGCGATCGTGTACGACGACCTGACGCTGAA
TCGCGCGACGCTCGGCGGCGTCGGCGGCACCTTGCTCGACAACGTCAAGGCAGGCGCGATCGCGGCGAGCAGCATGCAGG
CCGTCAACGGCGCGCAGCTCTTCTCGATGCAGCAGCAATTCGAAACGCGCCTGGAATCGCTCGACACGCGCATCAAGAAC
ATCGAGCAGGTCGGCCCGAACACCCGGCCGCCGACCGGCGAGCAGGGCGGCCAGCTGGCGCAGCTGGGCGACGGCTCCGG
CGCGACCGGCTCGGACTCGATGGCGCCCGGCCCGAACTCGAGCGCATCCGGCAACGGCAGCCTCGCGATCGGCAACAACA
CGACGGCGCCGGGCAACAATTCGGTGGCACTCGGCAACGGCTCCGTCGCCGATCGCGACAACACGGTGTCCGTCGGCGCG
CCGGGGCAGGAGCGGCAGATCACCAACGTCAAGGCCGGCACCGCGCCGACCGACGCCGTGAACGTGCAGCAACTGAACGA
CCACATCGGCAGCGTTCGTTCCGACATGGATCATTACCGGCGCGACGCGAGCGGCGGTATTGCGTCGGCGGTGGCGATCG
CGAACTTGCCGCAGGCATCGCTGGCAGGCGAAAGCATGGTGGCGATCGCCGGCGGCACCTACAGCGGGCAGTCGGCCGTC
GCGTTCGGCCTGTCGACCGCCACCCGCAACGGGCGCTGGGTGGTCAAGGCGTCCGGGTCGACCAATACCCGCGGCACGGT
CGCGGTCGGCGCCGGCGCCGGCTATCGCTGGTAA

Upstream 100 bases:

>100_bases
CCGCTCACACGCCACCACACTTCGCCCCCGCCTTTCGACGAAGCCGCACAGGCGTCATCCGGCTGCGTCACGCATAACGT
TGATCAGGACTACGATTAAT

Downstream 100 bases:

>100_bases
CGCGTCACGGCGACATCGCCCGCATCAAGCAACAGGGGCCGGGGTTCGATCGATACGAACCTCGGCCCCTTCGCACTCGC
TGCACGGACGCCAAACACCG

Product: YadA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MSGISAAHSRTTRARSHASLKRQRTPSARLSALALAIAALAPCYGHASGTDLVETNLIVKGGDSGDPIASGAGSIAIGAG
AKATGETGGDYSAIAIGDRAVANGRSTIAVGEAANVHGDRSSAFGVSSSVNANRALALGADAKVTAHGAVALGQGSVADR
TNTVSIGTADTQRQLVNLGAGTRDTDATNLSQLKPVVAALGGDAAVNADGTVRGPNYTVDGRSFNTVGGALTQLDGRVTT
IDGRVTTVENNVTSIRNDVTDLGTRLDNGTTGLVRQDPANLAISIGADKGGTSVSVAGTDGTRTLTGLSNGTGDTDAVTV
AQLKATGLIDPNGKALGAIVYDDLTLNRATLGGVGGTLLDNVKAGAIAASSMQAVNGAQLFSMQQQFETRLESLDTRIKN
IEQVGPNTRPPTGEQGGQLAQLGDGSGATGSDSMAPGPNSSASGNGSLAIGNNTTAPGNNSVALGNGSVADRDNTVSVGA
PGQERQITNVKAGTAPTDAVNVQQLNDHIGSVRSDMDHYRRDASGGIASAVAIANLPQASLAGESMVAIAGGTYSGQSAV
AFGLSTATRNGRWVVKASGSTNTRGTVAVGAGAGYRW

Sequences:

>Translated_597_residues
MSGISAAHSRTTRARSHASLKRQRTPSARLSALALAIAALAPCYGHASGTDLVETNLIVKGGDSGDPIASGAGSIAIGAG
AKATGETGGDYSAIAIGDRAVANGRSTIAVGEAANVHGDRSSAFGVSSSVNANRALALGADAKVTAHGAVALGQGSVADR
TNTVSIGTADTQRQLVNLGAGTRDTDATNLSQLKPVVAALGGDAAVNADGTVRGPNYTVDGRSFNTVGGALTQLDGRVTT
IDGRVTTVENNVTSIRNDVTDLGTRLDNGTTGLVRQDPANLAISIGADKGGTSVSVAGTDGTRTLTGLSNGTGDTDAVTV
AQLKATGLIDPNGKALGAIVYDDLTLNRATLGGVGGTLLDNVKAGAIAASSMQAVNGAQLFSMQQQFETRLESLDTRIKN
IEQVGPNTRPPTGEQGGQLAQLGDGSGATGSDSMAPGPNSSASGNGSLAIGNNTTAPGNNSVALGNGSVADRDNTVSVGA
PGQERQITNVKAGTAPTDAVNVQQLNDHIGSVRSDMDHYRRDASGGIASAVAIANLPQASLAGESMVAIAGGTYSGQSAV
AFGLSTATRNGRWVVKASGSTNTRGTVAVGAGAGYRW
>Mature_596_residues
SGISAAHSRTTRARSHASLKRQRTPSARLSALALAIAALAPCYGHASGTDLVETNLIVKGGDSGDPIASGAGSIAIGAGA
KATGETGGDYSAIAIGDRAVANGRSTIAVGEAANVHGDRSSAFGVSSSVNANRALALGADAKVTAHGAVALGQGSVADRT
NTVSIGTADTQRQLVNLGAGTRDTDATNLSQLKPVVAALGGDAAVNADGTVRGPNYTVDGRSFNTVGGALTQLDGRVTTI
DGRVTTVENNVTSIRNDVTDLGTRLDNGTTGLVRQDPANLAISIGADKGGTSVSVAGTDGTRTLTGLSNGTGDTDAVTVA
QLKATGLIDPNGKALGAIVYDDLTLNRATLGGVGGTLLDNVKAGAIAASSMQAVNGAQLFSMQQQFETRLESLDTRIKNI
EQVGPNTRPPTGEQGGQLAQLGDGSGATGSDSMAPGPNSSASGNGSLAIGNNTTAPGNNSVALGNGSVADRDNTVSVGAP
GQERQITNVKAGTAPTDAVNVQQLNDHIGSVRSDMDHYRRDASGGIASAVAIANLPQASLAGESMVAIAGGTYSGQSAVA
FGLSTATRNGRWVVKASGSTNTRGTVAVGAGAGYRW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes attachment to eukaryotic cells and after invasion, is the major adhesin in infected tissue. Constitutes an alternative uptake pathway under conditio

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 59249; Mature: 59117

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGISAAHSRTTRARSHASLKRQRTPSARLSALALAIAALAPCYGHASGTDLVETNLIVK
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEE
GGDSGDPIASGAGSIAIGAGAKATGETGGDYSAIAIGDRAVANGRSTIAVGEAANVHGDR
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCC
SSAFGVSSSVNANRALALGADAKVTAHGAVALGQGSVADRTNTVSIGTADTQRQLVNLGA
CCCCCCCCCCCCCEEEEECCCCEEEECCEEEECCCCCCCCCCEEEECCCHHHHHHHHCCC
GTRDTDATNLSQLKPVVAALGGDAAVNADGTVRGPNYTVDGRSFNTVGGALTQLDGRVTT
CCCCCCCCCHHHHHHHHHHCCCCEEECCCCEECCCCEEECCCCCCCCCCHHHHCCCEEEE
IDGRVTTVENNVTSIRNDVTDLGTRLDNGTTGLVRQDPANLAISIGADKGGTSVSVAGTD
ECCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCCEEEEECCC
GTRTLTGLSNGTGDTDAVTVAQLKATGLIDPNGKALGAIVYDDLTLNRATLGGVGGTLLD
CCEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCEEEEEEEECEEECCEEECCCCHHHHH
NVKAGAIAASSMQAVNGAQLFSMQQQFETRLESLDTRIKNIEQVGPNTRPPTGEQGGQLA
CCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
QLGDGSGATGSDSMAPGPNSSASGNGSLAIGNNTTAPGNNSVALGNGSVADRDNTVSVGA
EECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCEEEECC
PGQERQITNVKAGTAPTDAVNVQQLNDHIGSVRSDMDHYRRDASGGIASAVAIANLPQAS
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHH
LAGESMVAIAGGTYSGQSAVAFGLSTATRNGRWVVKASGSTNTRGTVAVGAGAGYRW
CCCCEEEEEECCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SGISAAHSRTTRARSHASLKRQRTPSARLSALALAIAALAPCYGHASGTDLVETNLIVK
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEE
GGDSGDPIASGAGSIAIGAGAKATGETGGDYSAIAIGDRAVANGRSTIAVGEAANVHGDR
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCC
SSAFGVSSSVNANRALALGADAKVTAHGAVALGQGSVADRTNTVSIGTADTQRQLVNLGA
CCCCCCCCCCCCCEEEEECCCCEEEECCEEEECCCCCCCCCCEEEECCCHHHHHHHHCCC
GTRDTDATNLSQLKPVVAALGGDAAVNADGTVRGPNYTVDGRSFNTVGGALTQLDGRVTT
CCCCCCCCCHHHHHHHHHHCCCCEEECCCCEECCCCEEECCCCCCCCCCHHHHCCCEEEE
IDGRVTTVENNVTSIRNDVTDLGTRLDNGTTGLVRQDPANLAISIGADKGGTSVSVAGTD
ECCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCCEEEEECCC
GTRTLTGLSNGTGDTDAVTVAQLKATGLIDPNGKALGAIVYDDLTLNRATLGGVGGTLLD
CCEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCEEEEEEEECEEECCEEECCCCHHHHH
NVKAGAIAASSMQAVNGAQLFSMQQQFETRLESLDTRIKNIEQVGPNTRPPTGEQGGQLA
CCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
QLGDGSGATGSDSMAPGPNSSASGNGSLAIGNNTTAPGNNSVALGNGSVADRDNTVSVGA
EECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCEEEECC
PGQERQITNVKAGTAPTDAVNVQQLNDHIGSVRSDMDHYRRDASGGIASAVAIANLPQAS
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHH
LAGESMVAIAGGTYSGQSAVAFGLSTATRNGRWVVKASGSTNTRGTVAVGAGAGYRW
CCCCEEEEEECCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3043229; 2761389; 2592347; 1548243; 12183532 [H]