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The map label for this gene is ctaD [H]

Identifier: 116690866

GI number: 116690866

Start: 3145552

End: 3147159

Strand: Reverse

Name: ctaD [H]

Synonym: Bcen2424_2846

Alternate gene names: 116690866

Gene position: 3147159-3145552 (Counterclockwise)

Preceding gene: 116690867

Following gene: 116690865

Centisome position: 90.33

GC content: 64.18

Gene sequence:

>1608_bases
ATGTCTAGCATCGGGCACGACGTAGCCGCGGACCACGCGCACGACGACCACGCGCACGAAGCCCCGCACGGCTGGCGTCG
CTGGCTGTTCGCCACCAACCACAAGGACATCGGTACGCTGTACCTGCTGTTCTCGTTCATCATGTTCCTGTCGGGCGGCG
TGATGGCGCTCGGCATCCGTGCCGAGCTGTTCGAGCCGGGCCTGCAGATCATGCGTCCGGAGTTCTTCAACGAACTCACG
ACGATGCACGGCCTGATCATGGTGTTCGGCGCGATCATGCCGGCGTTCGTCGGCTTCGCGAACTGGATGATTCCGCTGCA
GATCGGCGCATCCGACATGGCGTTCGCGCGGATGAACAACTTCAGCTTCTGGCTGCTGCCGGTCGCGGCCGTGCTGCTGG
TCGGCTCGTTCTTCGCGCCGGGCGGCGCGACGGCTGCCGGCTGGACGCTGTACGCACCGCTGTCGACGCAGATGGGCCCG
GGCATGGACTTCGCGATCTTCGCGGTCCACATCATGGGCGCATCGTCGATCATGGGCGGGATCAACATCGTCGTGACGAT
CCTGAACATGCGTGCACCGGGCATGACGCTGATGAAGATGCCGATGTTCGCGTGGACGTGGCTGATCACCGCGTACCTGC
TGATCGCCGTGATGCCGGTTCTGGCGGGCGCGATCACGATGGTGCTGTTCGACCGCCACTTCGGCACGTCGTTCTTCAAC
GCGGCAGGCGGCGGCGACCCGGTGATGTACCAGCACATCTTCTGGTTCTTCGGCCACCCCGAGGTGTACATCATGATTCT
GCCGGCGTTCGGGATCGTGTCGCAGGTGATCCCGGCGTTCGCACGCAAGACGCTGTTCGGCTACAGCTCGATGGTGTACG
CGACGGCATCGATCGCGATCCTGTCGTTCATGGTCTGGGCGCACCACATGTTCGCCACGGGCATGCCGGTCACCGGCCAG
CTGTTCTTCATGTACGCGACGATGCTGATCGCGGTGCCGACGGGCGTGAAGGTGTTCAACTGGCTCGCGACGATGTGGCG
CGGCTCGATGACGTTCGAAACCCCGATGCTGTTCGCGATCGGCTTCCTGTTCGTGTTCACGTTCGGCGGCCTGACGGGCC
TGATGCTCGCGATGGCGCCGCTCGACATCCAGTATCACGGCACCTACTTCGTGGTCGCGCACTTCCACTACGTGCTGGTG
GCCGGCTCGCTGTTCGCGCTGTTCTCGGGCTGGTACTACTGGGCGCCGAAGTGGACGGGCTGGATGTACAACGAGACGCG
CGGCAAGATCCACTTCTGGGCGTCGATGATCTTCTTCAACCTGACGTTCTTCCCGATGCACTTCGTCGGTCTCGCGGGCA
TGCCGCGCCGCTATGCGGATTACCCGGCGCAGTTCACGGACTTCAACCAGGTGGCGACGATCGGCGCATTCGGCTTCGGC
CTCGCGCAGGTGTACTTCCTGTTCGCGGTCGCGCTGCCGGCCTACCGTGGCGGCGGCGAGCTGGAAAAGGCGTCGGACAA
GCCGTGGGATGGCGCGACGGGCCTCGAGTGGACGGTACCGAGCCCGGCTCCGTTCCACACGTTCGAGCAACCGCCGCACG
TCGAATAA

Upstream 100 bases:

>100_bases
ACGGGCGGGGCTGACGCGAAGGAAGCCCGGCGTGTCGAGATCGGCCCGGCGGCTTGACGTGTCGCTGAGTTAGTCGACGT
ATTCGCATTAGGAGATTCTC

Downstream 100 bases:

>100_bases
GTTTCACCGAGCGTTCCGCCGCTGCCTGCCGCGCAGGCAGGCGCGGCGGGCGCGGAACGGAAGTTTCAGCGAAGTTTCAG
ATGACCCGGAATCCACCAGA

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MSSIGHDVAADHAHDDHAHEAPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFEPGLQIMRPEFFNELT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFSGWYYWAPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
LAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE

Sequences:

>Translated_535_residues
MSSIGHDVAADHAHDDHAHEAPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFEPGLQIMRPEFFNELT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFSGWYYWAPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
LAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE
>Mature_534_residues
SSIGHDVAADHAHDDHAHEAPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFEPGLQIMRPEFFNELTT
MHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPG
MDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFNA
AGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQL
FFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVA
GSLFALFSGWYYWAPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFGL
AQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=517, Percent_Identity=49.1295938104449, Blast_Score=458, Evalue=1e-129,
Organism=Escherichia coli, GI1786634, Length=518, Percent_Identity=40.7335907335907, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=47.6459510357815, Blast_Score=483, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=50.1547987616099, Blast_Score=327, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=46.9635627530364, Blast_Score=216, Evalue=9e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59478; Mature: 59346

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIGHDVAADHAHDDHAHEAPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIR
CCCCCCCHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHH
AELFEPGLQIMRPEFFNELTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFSGWYYWAPKWTG
HHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCC
WMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSIGHDVAADHAHDDHAHEAPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIR
CCCCCCHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHH
AELFEPGLQIMRPEFFNELTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFSGWYYWAPKWTG
HHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCC
WMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]