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The map label for this gene is glpK [H]

Identifier: 116690698

GI number: 116690698

Start: 2967393

End: 2968895

Strand: Direct

Name: glpK [H]

Synonym: Bcen2424_2678

Alternate gene names: 116690698

Gene position: 2967393-2968895 (Clockwise)

Preceding gene: 116690697

Following gene: 116690699

Centisome position: 85.17

GC content: 66.47

Gene sequence:

>1503_bases
ATGCAGGACCAGTACATCCTCGCGCTTGACCAGGGCACCACGAGTTCCCGCGCGATGCTGTTCGATCGCCAGGGCAACAT
CGTATCGATCGCCCAGAAGGAATTCGAACAGATCTACCCGCAACCCGGCTGGGTCGAGCACGACCCGCAGGAAATCTGGT
CGACGCAAGCCGGCGTCGCCGCGGAAGCCGTCACGCGCACGGGCCTGAACGGCACGTCGATCGCCGCGATCGGCATCACG
AACCAGCGCGAAACGACCATCGTCTGGGATCGCGAGACGGGCCAGCCCGTCTACAACGCGATCGTCTGGCAGGATCGCCG
CACGGCCGACTTCTGCGACTCGCTGAAGAAGCAGGGCCTCGAAGCGAAGGTGCGCGCGAAGACCGGCCTGCCGATCGACT
CGTACTTCTCCGCGACGAAGATCCGCTGGATTCTGGACAACGTGCCGGGTGCACGCGACAAGGCGCGCCAGGGCAAGCTC
GCGTTCGGCACCGTCGACAGCTGGCTCGTGTGGAACTTCACGAAGCACGAACTGCACGTGACCGACGTGACGAACGCATC
GCGCACGATGCTGTTCAACATCCATACGCGCGAATGGGACAGCGAGCTGCTCGAACTGCTCGACATCCCGCGCAGCATGC
TGCCGGAAGTGAAGGCATCGTCGGAAATCTACGGCCACACCAAGACCACCGTGTTCGCGTCGAAGATCCCGCTCGCGGGC
ATCGCCGGCGACCAGCACGCGGCGCTGTTCGGCCAGATGTGCACGACGTCGGGCATGGTGAAGAACACCTACGGCACCGG
CTGCTTCCTGATGATGAACACCGGCGACAAGCCGATCGAATCGAAGAACAACCTCGTCACGACGATCGCCTGGCAGATCG
GCGATGACGTGCAGTACGCGCTCGAAGGCAGCATCTTCATCGCGGGCGCGGTCGTGCAGTGGCTGCGCGACGGCGTCGGC
CTCATCAAGACGGCCGCGGAAATCGAGGCGCTCGCCGCGAGCGTGCCGCACACCGACGGCGTGTATCTCGTGCCCGCGTT
CGCCGGTCTCGGCGCGCCGCACTGGAACGCGCGGGCGCGCGGCTCGGTGTTCGGCGTCACGCGCGGTACGAGCGCCGCGC
ATCTCGCGCGCGCGGCGCTCGATGCGATCGCGTATCAGTCGCTCGACGTGCTGGCCGCGATGGAAGCCGATTCGGGTATC
AGCATCGGCGAGTTGCGCGTCGATGGCGGCGCCAGCGCGAACGACCTGCTGATGCAGTTCCAGGCCGACCTGCTCGGCGT
CGACGCGGTGCGTCCGCAGATCACCGAGACGACCGCGCTCGGCGCGGCCTACCTCGCGGGTCTCGCGATCGGCTACTGGA
AGAACCTCGACGAAGTGCGCGACCAGTGGCAGCTCGATCGCCGCTTCGCACCGTCGATGCCGAAGGAGCAGGTCGAGCAG
CGCATGGCCGGCTGGCAGCGTGCGGTGCGCGCCGCGAAGGCATGGGCCGACGACACCCAGTAA

Upstream 100 bases:

>100_bases
GCAATGGTAGTTTTGCCTGACCGACGTTGATTCACCGACGCGCCGCCCCACATGCGGCGCGCATCACAACTAAGCCAATC
CACGGATGGAGATGAGAGAC

Downstream 100 bases:

>100_bases
TCCGAATAAAACCAAACGAAATACAACAACACCGGCGGACCGCGCGATGCGCGAGTCCGCCGTGACTTCGAGAGACAATC
ATGTCACCTTATATTGCAGA

Product: glycerol kinase

Products: NA

Alternate protein names: ATP:glycerol 3-phosphotransferase; Glycerokinase; GK [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGIT
NQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPEVKASSEIYGHTKTTVFASKIPLAG
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVG
LIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTSAAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRDQWQLDRRFAPSMPKEQVEQ
RMAGWQRAVRAAKAWADDTQ

Sequences:

>Translated_500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGIT
NQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPEVKASSEIYGHTKTTVFASKIPLAG
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVG
LIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTSAAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRDQWQLDRRFAPSMPKEQVEQ
RMAGWQRAVRAAKAWADDTQ
>Mature_500_residues
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGIT
NQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKL
AFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPEVKASSEIYGHTKTTVFASKIPLAG
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVG
LIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTSAAHLARAALDAIAYQSLDVLAAMEADSGI
SIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRDQWQLDRRFAPSMPKEQVEQ
RMAGWQRAVRAAKAWADDTQ

Specific function: Key enzyme in the regulation of glycerol uptake and metabolism [H]

COG id: COG0554

COG function: function code C; Glycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI4504007, Length=502, Percent_Identity=46.2151394422311, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI189409120, Length=502, Percent_Identity=46.2151394422311, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI42794763, Length=507, Percent_Identity=45.7593688362919, Blast_Score=450, Evalue=1e-126,
Organism=Homo sapiens, GI41393575, Length=502, Percent_Identity=44.4223107569721, Blast_Score=440, Evalue=1e-123,
Organism=Homo sapiens, GI88196792, Length=511, Percent_Identity=32.6810176125245, Blast_Score=311, Evalue=1e-84,
Organism=Escherichia coli, GI1790361, Length=497, Percent_Identity=59.1549295774648, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=501, Percent_Identity=25.1497005988024, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789987, Length=492, Percent_Identity=24.1869918699187, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789168, Length=495, Percent_Identity=25.2525252525253, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787789, Length=501, Percent_Identity=25.3493013972056, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=500, Percent_Identity=44, Blast_Score=423, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI71986140, Length=515, Percent_Identity=23.495145631068, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71986147, Length=294, Percent_Identity=27.5510204081633, Blast_Score=118, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6321755, Length=555, Percent_Identity=35.4954954954955, Blast_Score=313, Evalue=5e-86,
Organism=Drosophila melanogaster, GI17864214, Length=508, Percent_Identity=41.9291338582677, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24655555, Length=473, Percent_Identity=42.0718816067653, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655560, Length=473, Percent_Identity=42.0718816067653, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655570, Length=473, Percent_Identity=42.0718816067653, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655574, Length=473, Percent_Identity=42.0718816067653, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24655565, Length=473, Percent_Identity=42.0718816067653, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24654573, Length=434, Percent_Identity=43.3179723502304, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19922058, Length=527, Percent_Identity=33.0170777988615, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24652871, Length=494, Percent_Identity=33.8056680161943, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI24656367, Length=514, Percent_Identity=31.3229571984436, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI21357867, Length=526, Percent_Identity=30.4182509505703, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24656372, Length=358, Percent_Identity=31.5642458100559, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI45552909, Length=298, Percent_Identity=29.1946308724832, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR005999 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.30 [H]

Molecular weight: Translated: 54661; Mature: 54661

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVA
CCCCEEEEEECCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHH
AEAVTRTGLNGTSIAAIGITNQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGL
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEECCCCCHHHHHHHHHCCC
EAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKLAFGTVDSWLVWNFTKHELHV
CEEEEECCCCCHHHHHHHHEEEEEECCCCCCCCHHHCCCEEEECCCCEEEEEEECCEEEE
TDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPEVKASSEIYGHTKTTVFASKIPLAG
EECCCCCEEEEEEEECCHHHHHHHHHHHCCHHHCCCCCCCCHHCCCCEEEEEECCCCEEE
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYA
CCCCCHHHHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEE
LEGSIFIAGAVVQWLRDGVGLIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARAR
ECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCC
GSVFGVTRGTSAAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANDLLMQF
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHH
QADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRDQWQLDRRFAPSMPKEQVEQ
HHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
RMAGWQRAVRAAKAWADDTQ
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVA
CCCCEEEEEECCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHH
AEAVTRTGLNGTSIAAIGITNQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGL
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHEEECCCCCHHHHHHHHHCCC
EAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKLAFGTVDSWLVWNFTKHELHV
CEEEEECCCCCHHHHHHHHEEEEEECCCCCCCCHHHCCCEEEECCCCEEEEEEECCEEEE
TDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPEVKASSEIYGHTKTTVFASKIPLAG
EECCCCCEEEEEEEECCHHHHHHHHHHHCCHHHCCCCCCCCHHCCCCEEEEEECCCCEEE
IAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYA
CCCCCHHHHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEE
LEGSIFIAGAVVQWLRDGVGLIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARAR
ECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCC
GSVFGVTRGTSAAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANDLLMQF
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHH
QADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRDQWQLDRRFAPSMPKEQVEQ
HHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
RMAGWQRAVRAAKAWADDTQ
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA