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The map label for this gene is yafC [H]

Identifier: 116690610

GI number: 116690610

Start: 2868072

End: 2868956

Strand: Direct

Name: yafC [H]

Synonym: Bcen2424_2590

Alternate gene names: 116690610

Gene position: 2868072-2868956 (Clockwise)

Preceding gene: 116690607

Following gene: 116690619

Centisome position: 82.32

GC content: 68.93

Gene sequence:

>885_bases
ATGGAAAATCTTGGCGGCTTCGTCGTGTTCGTCCAGGTCGCGGAAACGCGCAGCTTCGTCGCGGCCGGCCGAGCGCTCGG
ACTGTCGGCATCGGCGATCGGCAAGCGCATCGCGCGGCTCGAGGCACGCCTGAACGTGCGGCTCTTTCACCGCAGCACGC
GCAGCATCACGCTGACGGCCGAAGGCACGCGCTTTCTCGAACGATGCCGGCGCGTGATCGCCGAAATCGACGCGGCCGAG
CAGGAACTGACGCAGAGCGTCGAGGCGCCGCGCGGGCGGCTGCGCGTGAGCCTGCCGACGATCGGCACGTTGCTACTGCC
GGTGCTCGCCGATTTCATGGCCGCGTATCCGGAGATCGAGCTCGACATCGATTTCAGCGACCGGATCGTCGACGTGATCG
ACGAAGGCTTCGACGTGGTACTGCGCACCGGCCATCCGACCGATTCCCGGCTGTCGTCGCGGCTGCTCGGCCACTTCCGC
CAGCACCTGGTCGCGTCGCCCGACTATCTCGAACGGCACGGCACGCCGCGCACGCCGGCCGACCTCGCGCAGCACCGCTG
CCTGCATTACCGATTCCCGAGCAGCGGCAAGCTCGAGATCTGGCCGCTGCGCGCGCCGCGCGCCGGCACGCCGCCGGAGG
TACCCGTCTCGATGGTCAGCAACAACGCCGAGACGCGCCTGTGCTTCGCGCTGCGCGGGCTCGGCATCGCGTGCCTGCCC
GAGTTCTTCGTGCGCGACACGCTCGCCGACGGCAGGCTGCGCGCAGTGCTCGACGATCACGTCGCGAGCCGCACGCCGTT
CTACGTGCTATGGCCGTCGGGCCGCCATCCGCTGCCCAAGCTGCGCGCGTTCGTCGACTACATGGCCGAGCATTTGCGGC
TGTAA

Upstream 100 bases:

>100_bases
ACAGTGAAGGAACGCCCATCGTAGGGAGCCGGCACGAGAAGAAAAATCGGGTTAGAGTTCCGGACACTCCGGACATGGGT
GTCCGCAATCGGGAACCTGC

Downstream 100 bases:

>100_bases
CCGGCGCGCGGCCGTCAAGCCGCCTTCGCGTGCGCGCTGAGCCGCCGCAGCGCCTGCCCGTGCTCGTCGAACAGGTGGCA
GTGCTCGGCCTGCGCATGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MENLGGFVVFVQVAETRSFVAAGRALGLSASAIGKRIARLEARLNVRLFHRSTRSITLTAEGTRFLERCRRVIAEIDAAE
QELTQSVEAPRGRLRVSLPTIGTLLLPVLADFMAAYPEIELDIDFSDRIVDVIDEGFDVVLRTGHPTDSRLSSRLLGHFR
QHLVASPDYLERHGTPRTPADLAQHRCLHYRFPSSGKLEIWPLRAPRAGTPPEVPVSMVSNNAETRLCFALRGLGIACLP
EFFVRDTLADGRLRAVLDDHVASRTPFYVLWPSGRHPLPKLRAFVDYMAEHLRL

Sequences:

>Translated_294_residues
MENLGGFVVFVQVAETRSFVAAGRALGLSASAIGKRIARLEARLNVRLFHRSTRSITLTAEGTRFLERCRRVIAEIDAAE
QELTQSVEAPRGRLRVSLPTIGTLLLPVLADFMAAYPEIELDIDFSDRIVDVIDEGFDVVLRTGHPTDSRLSSRLLGHFR
QHLVASPDYLERHGTPRTPADLAQHRCLHYRFPSSGKLEIWPLRAPRAGTPPEVPVSMVSNNAETRLCFALRGLGIACLP
EFFVRDTLADGRLRAVLDDHVASRTPFYVLWPSGRHPLPKLRAFVDYMAEHLRL
>Mature_294_residues
MENLGGFVVFVQVAETRSFVAAGRALGLSASAIGKRIARLEARLNVRLFHRSTRSITLTAEGTRFLERCRRVIAEIDAAE
QELTQSVEAPRGRLRVSLPTIGTLLLPVLADFMAAYPEIELDIDFSDRIVDVIDEGFDVVLRTGHPTDSRLSSRLLGHFR
QHLVASPDYLERHGTPRTPADLAQHRCLHYRFPSSGKLEIWPLRAPRAGTPPEVPVSMVSNNAETRLCFALRGLGIACLP
EFFVRDTLADGRLRAVLDDHVASRTPFYVLWPSGRHPLPKLRAFVDYMAEHLRL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=36.551724137931, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=33.6769759450172, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=31.5254237288136, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=31.4189189189189, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=32.2033898305085, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=28.9655172413793, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=28.719723183391, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788706, Length=297, Percent_Identity=26.5993265993266, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789173, Length=290, Percent_Identity=27.2413793103448, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1786448, Length=287, Percent_Identity=27.1777003484321, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790011, Length=252, Percent_Identity=25.3968253968254, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI157672245, Length=128, Percent_Identity=35.15625, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI145693105, Length=256, Percent_Identity=25.390625, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=233, Percent_Identity=28.755364806867, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=24.2320819112628, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=29.6875, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32893; Mature: 32893

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLGGFVVFVQVAETRSFVAAGRALGLSASAIGKRIARLEARLNVRLFHRSTRSITLTA
CCCCCCEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCCCEEEEEE
EGTRFLERCRRVIAEIDAAEQELTQSVEAPRGRLRVSLPTIGTLLLPVLADFMAAYPEIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEE
LDIDFSDRIVDVIDEGFDVVLRTGHPTDSRLSSRLLGHFRQHLVASPDYLERHGTPRTPA
EECCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHH
DLAQHRCLHYRFPSSGKLEIWPLRAPRAGTPPEVPVSMVSNNAETRLCFALRGLGIACLP
HHHHCCCEEEECCCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCHHHHH
EFFVRDTLADGRLRAVLDDHVASRTPFYVLWPSGRHPLPKLRAFVDYMAEHLRL
HHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENLGGFVVFVQVAETRSFVAAGRALGLSASAIGKRIARLEARLNVRLFHRSTRSITLTA
CCCCCCEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCCCEEEEEE
EGTRFLERCRRVIAEIDAAEQELTQSVEAPRGRLRVSLPTIGTLLLPVLADFMAAYPEIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEE
LDIDFSDRIVDVIDEGFDVVLRTGHPTDSRLSSRLLGHFRQHLVASPDYLERHGTPRTPA
EECCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHH
DLAQHRCLHYRFPSSGKLEIWPLRAPRAGTPPEVPVSMVSNNAETRLCFALRGLGIACLP
HHHHCCCEEEECCCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCHHHHH
EFFVRDTLADGRLRAVLDDHVASRTPFYVLWPSGRHPLPKLRAFVDYMAEHLRL
HHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]