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The map label for this gene is lspA [H]

Identifier: 116690533

GI number: 116690533

Start: 2784807

End: 2785307

Strand: Direct

Name: lspA [H]

Synonym: Bcen2424_2513

Alternate gene names: 116690533

Gene position: 2784807-2785307 (Clockwise)

Preceding gene: 116690532

Following gene: 116690534

Centisome position: 79.93

GC content: 66.67

Gene sequence:

>501_bases
ATGGCGAAGACCCTGTCGAAACCGGCCAGCGGCGCGCTCGCGCCCTGGCTCGGTATTTCGCTGATCGTGATCCTGTTCGA
CCAGCTGTCGAAGATCGCGATCCTGAAAACGTTCGCGTACGGCGCGCAGCATGCGCTGACGTCGTTCTTCAACCTCGTGC
TGGTGTACAACCGCGGCGCCGCATTCGGCTTCCTGTCGACCGCGAGCGGCTGGCAGCGCTGGGCGTTCACCGCGCTCGGC
GTCGGCGCGACGCTCGTGATCTGCTTCCTGCTGAAGCGCCACGGCCACCAGCGGCTGTTCAGCGTGTCGCTCGCGCTGAT
CCTCGGCGGCGCGCTCGGCAACGTGATCGACCGGCTCGTCTACGGTCACGTGATCGACTTCCTCGATTTCCACCTCGGCG
CGTGGCACTTCCCGGCATTCAACCTCGCCGATTCCGCGATCACGGTCGGCGCGGTGCTGCTGATCTACGACGAGCTGCGT
CGCGTGCGCGGCGCGCGCTGA

Upstream 100 bases:

>100_bases
ACCGCGAAGATGTCGGCGCGCACGCCGAGCACCCGACGCTGTGCGGCCGCTGCTTCTCGAACCTGTTTGAAAACGGCGAA
ATCCGGAGCGCTGCTTAAAT

Downstream 100 bases:

>100_bases
GCGCGCATACTCCGTGTCGACGGCCGGCTTCGCGCCGGCCGTTCCGTTTGACCCCCAGGAGGCCTGAGTTGGCACACGCA
GAACTTGCAGGAAAACACCT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGAAFGFLSTASGWQRWAFTALG
VGATLVICFLLKRHGHQRLFSVSLALILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELR
RVRGAR

Sequences:

>Translated_166_residues
MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGAAFGFLSTASGWQRWAFTALG
VGATLVICFLLKRHGHQRLFSVSLALILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELR
RVRGAR
>Mature_165_residues
AKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGAAFGFLSTASGWQRWAFTALGV
GATLVICFLLKRHGHQRLFSVSLALILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELRR
VRGAR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=152, Percent_Identity=42.1052631578947, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18057; Mature: 17926

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AFGFLSTASGWQRWAFTALGVGATLVICFLLKRHGHQRLFSVSLALILGGALGNVIDRLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELRRVRGAR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AFGFLSTASGWQRWAFTALGVGATLVICFLLKRHGHQRLFSVSLALILGGALGNVIDRLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELRRVRGAR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA