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The map label for this gene is cysH1 [H]

Identifier: 116690493

GI number: 116690493

Start: 2744231

End: 2744980

Strand: Reverse

Name: cysH1 [H]

Synonym: Bcen2424_2473

Alternate gene names: 116690493

Gene position: 2744980-2744231 (Counterclockwise)

Preceding gene: 116690494

Following gene: 116690492

Centisome position: 78.79

GC content: 69.47

Gene sequence:

>750_bases
ATGAGCACCGCGACCGCCCCCGCGCTGACGCCGGAACTCGCCGCCAAGGTCGAGCGCCTCGACGCGCTGCTCGCGCAGAT
CGGCGAGCGTCACGACAAGGTGAAGTTCGCGAGCAGCCTCGCCGCGGAAGACATGCTGCTCACGCACGCGATCCTGTCGA
AGGGCGTGTCGATCGGCATCTTCTCGCTGAACACGGGCCGCCTGCACGCGGAGACGCTCGGCATGATCGACCGCGTGCGC
GAGCGCTACGGCTACGAGATCGAGCAGTTCCACCCGCGGCAGGACGCGGTCGACCAGTATGTCGCCGAGCACGGCCTGAA
CGCGTTCTACGAGAGCGTCGAGCTGCGCAAGTCGTGCTGCCACATCCGCAAGGTCGAGCCGCTGAACCGCGCGCTGGCCG
ACGTCGGCGCGTGGGTGACGGGCCAGCGCCGCGAGCAGTCGGTCACGCGCGCGGAGCTGCACGAGGAAGAACAGGACGAA
GCGCGCGGGATCGCGAAGTACAACCCGCTCGCCGACTGGACGGAAGCCGACGTGTGGGCGTACCTTAAGGCGTTTGACGT
GCCGGTCAACCCGCTGCATGCGCGCGGCTATCCGAGCATCGGCTGCGAGCCGTGCACGCGCGCGATCCGTCCCGGCGAGG
ACAGCCGCGCGGGCCGCTGGTGGTGGGAGTCGCGCGACACGAAGGAATGCGGGCTGCACATCACGATCACGCCGATTCCC
GCGGATGCCGAAGCCGGCGCCGCGCACTGA

Upstream 100 bases:

>100_bases
TGAATGCGTTCACGGAATTCACGCAGCGTTACCAGGGCGCGTTCGACGAGCCGGCGCCGCTGTTCCGCCGCCGCGAGGCG
GCTGCCGCCAAGGTGAGCGC

Downstream 100 bases:

>100_bases
ACGCCCGATAAGAAACTGAATATTGCGCCGCCTGCGACAGCGGGCGGCACGAACCCAGAAGAGAAGGACTGAAATCATGA
GCACGACGCTCGAGCAATCC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSTATAPALTPELAAKVERLDALLAQIGERHDKVKFASSLAAEDMLLTHAILSKGVSIGIFSLNTGRLHAETLGMIDRVR
ERYGYEIEQFHPRQDAVDQYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDE
ARGIAKYNPLADWTEADVWAYLKAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPIP
ADAEAGAAH

Sequences:

>Translated_249_residues
MSTATAPALTPELAAKVERLDALLAQIGERHDKVKFASSLAAEDMLLTHAILSKGVSIGIFSLNTGRLHAETLGMIDRVR
ERYGYEIEQFHPRQDAVDQYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDE
ARGIAKYNPLADWTEADVWAYLKAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPIP
ADAEAGAAH
>Mature_248_residues
STATAPALTPELAAKVERLDALLAQIGERHDKVKFASSLAAEDMLLTHAILSKGVSIGIFSLNTGRLHAETLGMIDRVRE
RYGYEIEQFHPRQDAVDQYVAEHGLNAFYESVELRKSCCHIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDEA
RGIAKYNPLADWTEADVWAYLKAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPIPA
DAEAGAAH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=227, Percent_Identity=29.9559471365639, Blast_Score=81, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325425, Length=115, Percent_Identity=42.6086956521739, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27767; Mature: 27636

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATAPALTPELAAKVERLDALLAQIGERHDKVKFASSLAAEDMLLTHAILSKGVSIGI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLGMIDRVRERYGYEIEQFHPRQDAVDQYVAEHGLNAFYESVELRKSCC
EEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDEARGIAKYNPLADWTEADVWA
HHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
YLKAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPIP
HHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEEEECC
ADAEAGAAH
CCCCCCCCC
>Mature Secondary Structure 
STATAPALTPELAAKVERLDALLAQIGERHDKVKFASSLAAEDMLLTHAILSKGVSIGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSLNTGRLHAETLGMIDRVRERYGYEIEQFHPRQDAVDQYVAEHGLNAFYESVELRKSCC
EEECCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIRKVEPLNRALADVGAWVTGQRREQSVTRAELHEEEQDEARGIAKYNPLADWTEADVWA
HHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
YLKAFDVPVNPLHARGYPSIGCEPCTRAIRPGEDSRAGRWWWESRDTKECGLHITITPIP
HHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEEEEEEECC
ADAEAGAAH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]