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The map label for this gene is cobT [H]

Identifier: 116690473

GI number: 116690473

Start: 2725114

End: 2726169

Strand: Reverse

Name: cobT [H]

Synonym: Bcen2424_2453

Alternate gene names: 116690473

Gene position: 2726169-2725114 (Counterclockwise)

Preceding gene: 116690474

Following gene: 116690472

Centisome position: 78.25

GC content: 70.74

Gene sequence:

>1056_bases
ATGACGACTCCCACCCCATTCCCGCCCGCGATCGCGCCGCTCGACGACGCGCTGCGCAAGCGCCTCCAACATGTGATCGA
CCACAAGACCAAGCCGCCCGGCAGTCTCGGCCAGCTCGAGGCGCTCGCGCTGCAGATCGGCCTGATCCAGCTAAGCGAGC
GGCCGGTCGTGCAGCGTCCGGTGACGATCGTGTTCGCGGGCGATCACGGAATCGCGGCCGAAGGCGTCAGTCCTTATCCG
CAGGCGGTGACTGCGCAGATGGTCGCGAACTTCCTGGCCGGCGGTGCGGCGATCAATGCGTTCTCGGGTGTCGCACAGAG
CACGCTCGAGATCGTCGATGCGGGCGTCGTATCGCCGCTGCCGGTATCGGACCGGCTGGTGTCGCTGCCGGTCGCGCGCG
GCACGCGCAACTTCGCGACGGAGCCGGCGATGACCCGTGAAGAAGCGATGACGGCGCTGGCCGCCGGCGCGGCGCGGGTA
CGCCTGCACGCGTCGCTCGGCACGAACGTGATCGGTTTCGGCGAGATGGGGATCGCGAACACGTCGTCGGCCGCGTGCCT
GATGAGCCGCCTGCTCGACGTGCCGATCGACGCCTGCGTCGGCCGCGGCACGGGCCTCGACGACCAGGGTCTCGCGCACA
AGCGCGCGGTGCTCGGCCGCGCGCTCGTCAAGCACTCGCATGCGATCGCGCCGCTCGACGTGCTCGCGACGTTCGGCGGC
TTCGAGATCGCGATGATGACGGGCGCGTACCTCGCGGCCGCGAGCGAGCGGATGACGATCCTCGTCGACGGCTTCATCGC
GACCGCCGCGCTGCTCGTCGCCGAGCGCATCGCGCCCGGCGTGCGCGACTACTGCGTGTTCTCGCATACGTCGCACGAGG
CCGGGCACCGGCGCATGCTCGAGCATTTCGGCGCGAAACCGCTGCTCGCGCTCGACCTGCGGCTCGGCGAAGGCACGGGC
GCAGCGCTCGCGCTGCCGCTGGTGCGCGCGGCGGCCGCGTTCCTCAGCGAGATGGCGAGCTTCGAGTCCGCCGGCGTCGA
CAATCGTGACGCCTGA

Upstream 100 bases:

>100_bases
CGCGATGCGCTGCTGCCGGCGTGGCCTGCGCGACAATGACCTTTCCTGTTCCGATTTTTCCGATGCGCGGCGCATGCCGC
GCCCACGACCCGGCTCCTCG

Downstream 100 bases:

>100_bases
GCGCGCGCGCGGCATGTGGGCCGAACTGCGCTACTTCTTCGTCGCGCTCGGCTATTTCACGCGCGTGCCCGTGCCGCGCT
CGATCGGCTACGCGGCCGGC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTTPTPFPPAIAPLDDALRKRLQHVIDHKTKPPGSLGQLEALALQIGLIQLSERPVVQRPVTIVFAGDHGIAAEGVSPYP
QAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVVSPLPVSDRLVSLPVARGTRNFATEPAMTREEAMTALAAGAARV
RLHASLGTNVIGFGEMGIANTSSAACLMSRLLDVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRMLEHFGAKPLLALDLRLGEGTG
AALALPLVRAAAAFLSEMASFESAGVDNRDA

Sequences:

>Translated_351_residues
MTTPTPFPPAIAPLDDALRKRLQHVIDHKTKPPGSLGQLEALALQIGLIQLSERPVVQRPVTIVFAGDHGIAAEGVSPYP
QAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVVSPLPVSDRLVSLPVARGTRNFATEPAMTREEAMTALAAGAARV
RLHASLGTNVIGFGEMGIANTSSAACLMSRLLDVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRMLEHFGAKPLLALDLRLGEGTG
AALALPLVRAAAAFLSEMASFESAGVDNRDA
>Mature_350_residues
TTPTPFPPAIAPLDDALRKRLQHVIDHKTKPPGSLGQLEALALQIGLIQLSERPVVQRPVTIVFAGDHGIAAEGVSPYPQ
AVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVVSPLPVSDRLVSLPVARGTRNFATEPAMTREEAMTALAAGAARVR
LHASLGTNVIGFGEMGIANTSSAACLMSRLLDVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGGF
EIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRMLEHFGAKPLLALDLRLGEGTGA
ALALPLVRAAAAFLSEMASFESAGVDNRDA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=338, Percent_Identity=35.7988165680473, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36455; Mature: 36323

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPTPFPPAIAPLDDALRKRLQHVIDHKTKPPGSLGQLEALALQIGLIQLSERPVVQRP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCC
VTIVFAGDHGIAAEGVSPYPQAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVVSPL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
PVSDRLVSLPVARGTRNFATEPAMTREEAMTALAAGAARVRLHASLGTNVIGFGEMGIAN
CCCCHHEECCHHCCCCCCCCCCCHHHHHHHHHHHHCHHHEEEEECCCCCEEEECCCCCCC
TSSAACLMSRLLDVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
CCHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRML
EEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHHHHH
EHFGAKPLLALDLRLGEGTGAALALPLVRAAAAFLSEMASFESAGVDNRDA
HHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTPTPFPPAIAPLDDALRKRLQHVIDHKTKPPGSLGQLEALALQIGLIQLSERPVVQRP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCC
VTIVFAGDHGIAAEGVSPYPQAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVVSPL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
PVSDRLVSLPVARGTRNFATEPAMTREEAMTALAAGAARVRLHASLGTNVIGFGEMGIAN
CCCCHHEECCHHCCCCCCCCCCCHHHHHHHHHHHHCHHHEEEEECCCCCEEEECCCCCCC
TSSAACLMSRLLDVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
CCHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRML
EEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHHHHH
EHFGAKPLLALDLRLGEGTGAALALPLVRAAAAFLSEMASFESAGVDNRDA
HHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA