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The map label for this gene is cobD [H]

Identifier: 116690468

GI number: 116690468

Start: 2720806

End: 2721744

Strand: Direct

Name: cobD [H]

Synonym: Bcen2424_2448

Alternate gene names: 116690468

Gene position: 2720806-2721744 (Clockwise)

Preceding gene: 116690467

Following gene: 116690469

Centisome position: 78.1

GC content: 74.87

Gene sequence:

>939_bases
ATGCTGTCGCTGCCCGTCGTCGCGATGCTCGCGGTCGCGGCCGCGATCGTCGACCGCGCCATCGGCGAGCCGGCCGGCTG
GCATCCGCTCGTCGCGTTCGGCCGCTTCGCCGCGCGCATCGAAGCCGCACTGAACACGGGCCGGCGCGGCCGCGTAATCG
GCGTCGCCGCGTGGCTCGCGGCGGTCGTGCCGCCGGTGGCCGTCGCGGCATGGCTCGTCGCCGTGCTGCCCTGGCCGTTC
GCCGCAGCGCTGCACGTCGCGCTGCTGTGGTTCGCGCTCGGCGCGAAGAGCCTCGCCGACCACGTCGCGCCGATCGCCGC
CGCGCTGCTGCGGCGCGACCTCGACGCGGCGCGCACGCTGACCGCGCGCATCGTGTCGCGCGACACGAGCCAGGCCGACG
AAGGAGCGCTGTCGCGCGCGGCCGTCGAATCGGCGCTCGAGAACGGCAACGACGCGATCTTCGGCGCGCTCTTCTGGTTC
GTCGTCGCGGGCGGCCCCGGCGCGCTGCTGTTCCGGCTCGCGAACACGCTCGACGCGATGTGGGGCTACCGCACGCCGCG
CTTCCTGACTTTCGGCTGGGCCGCCGCGCGCATCGACGACGCGCTGAACTGGATTCCCGCGCGGCTCACCGCCGCGAGCT
ACGCGCTGCTCGGCGACACGGCAGCCGCGTGGCGCTGCTGGCGCACGCAGGCGCGCCACTGGGACAGCCCGAACGCGGGC
CCCGTGATGGCCGCGGGCGCCGGCAGCCTGAACGTGCAGCTCGGCGGCCCGGCCGTCTATCACGGCGAAATCGAGGATCG
CCCGGTGCTCGGCACCGGGGCCACGGCCACCGCCCTTCACATCGTCGCCGCGCTGTCGCTGGTCACGCGCACGCTCGCGC
TGTGGCTCGCGCTGCTGGTCGCGAGCGGCGCACTCGTCATGGCCACCCATCATGTCTGA

Upstream 100 bases:

>100_bases
TCGGGCGCCTGAACCAGCGCGTCGCCGCGCTCGCGACGCGCGTCACGCTGCTGGTCGCCGGGCTGCCGCTCGACCTCAAG
GCAGGCGCGCCGTCATGCTG

Downstream 100 bases:

>100_bases
TTCATCCATCGCGCACGGCGGCAACCTGCATGAAGCCGCCCGCCGCCACGGCATTCCGTACGACGCGTGGCTCGACCTGT
CGACCGGCATCAATCCGGTC

Product: cobalamin biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MLSLPVVAMLAVAAAIVDRAIGEPAGWHPLVAFGRFAARIEAALNTGRRGRVIGVAAWLAAVVPPVAVAAWLVAVLPWPF
AAALHVALLWFALGAKSLADHVAPIAAALLRRDLDAARTLTARIVSRDTSQADEGALSRAAVESALENGNDAIFGALFWF
VVAGGPGALLFRLANTLDAMWGYRTPRFLTFGWAAARIDDALNWIPARLTAASYALLGDTAAAWRCWRTQARHWDSPNAG
PVMAAGAGSLNVQLGGPAVYHGEIEDRPVLGTGATATALHIVAALSLVTRTLALWLALLVASGALVMATHHV

Sequences:

>Translated_312_residues
MLSLPVVAMLAVAAAIVDRAIGEPAGWHPLVAFGRFAARIEAALNTGRRGRVIGVAAWLAAVVPPVAVAAWLVAVLPWPF
AAALHVALLWFALGAKSLADHVAPIAAALLRRDLDAARTLTARIVSRDTSQADEGALSRAAVESALENGNDAIFGALFWF
VVAGGPGALLFRLANTLDAMWGYRTPRFLTFGWAAARIDDALNWIPARLTAASYALLGDTAAAWRCWRTQARHWDSPNAG
PVMAAGAGSLNVQLGGPAVYHGEIEDRPVLGTGATATALHIVAALSLVTRTLALWLALLVASGALVMATHHV
>Mature_312_residues
MLSLPVVAMLAVAAAIVDRAIGEPAGWHPLVAFGRFAARIEAALNTGRRGRVIGVAAWLAAVVPPVAVAAWLVAVLPWPF
AAALHVALLWFALGAKSLADHVAPIAAALLRRDLDAARTLTARIVSRDTSQADEGALSRAAVESALENGNDAIFGALFWF
VVAGGPGALLFRLANTLDAMWGYRTPRFLTFGWAAARIDDALNWIPARLTAASYALLGDTAAAWRCWRTQARHWDSPNAG
PVMAAGAGSLNVQLGGPAVYHGEIEDRPVLGTGATATALHIVAALSLVTRTLALWLALLVASGALVMATHHV

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 32640; Mature: 32640

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLPVVAMLAVAAAIVDRAIGEPAGWHPLVAFGRFAARIEAALNTGRRGRVIGVAAWLA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AVVPPVAVAAWLVAVLPWPFAAALHVALLWFALGAKSLADHVAPIAAALLRRDLDAARTL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TARIVSRDTSQADEGALSRAAVESALENGNDAIFGALFWFVVAGGPGALLFRLANTLDAM
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
WGYRTPRFLTFGWAAARIDDALNWIPARLTAASYALLGDTAAAWRCWRTQARHWDSPNAG
HCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC
PVMAAGAGSLNVQLGGPAVYHGEIEDRPVLGTGATATALHIVAALSLVTRTLALWLALLV
CEEEECCCEEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGALVMATHHV
HCCCCEEEECCC
>Mature Secondary Structure
MLSLPVVAMLAVAAAIVDRAIGEPAGWHPLVAFGRFAARIEAALNTGRRGRVIGVAAWLA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AVVPPVAVAAWLVAVLPWPFAAALHVALLWFALGAKSLADHVAPIAAALLRRDLDAARTL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TARIVSRDTSQADEGALSRAAVESALENGNDAIFGALFWFVVAGGPGALLFRLANTLDAM
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
WGYRTPRFLTFGWAAARIDDALNWIPARLTAASYALLGDTAAAWRCWRTQARHWDSPNAG
HCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC
PVMAAGAGSLNVQLGGPAVYHGEIEDRPVLGTGATATALHIVAALSLVTRTLALWLALLV
CEEEECCCEEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGALVMATHHV
HCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]