| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
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The map label for this gene is fabG [H]
Identifier: 116690439
GI number: 116690439
Start: 2683001
End: 2683759
Strand: Direct
Name: fabG [H]
Synonym: Bcen2424_2419
Alternate gene names: 116690439
Gene position: 2683001-2683759 (Clockwise)
Preceding gene: 116690438
Following gene: 116690440
Centisome position: 77.01
GC content: 67.72
Gene sequence:
>759_bases ATGCGGTTGAGCGGCAAGACGGCCATCGTCACGGGCGGCGGCTCGGGGTTCGGCGAAGGCATCGCGAAGACCTATGCGCG CGAAGGCGCGAACGTCGTCGTCAACGACCTGAACGGCGCGGCGGCCGAGCGCGTCGCGAGCGAGATCGCGCTCGCGGGCG GCAAGGCGATCGCGGTGGCCGGCGACGTGTCGAAAGAGGACGACTGGCGCGCGCTGCTGCAGGCCGCGCTCGAGGATTTC CATGCGGTGCAGATCGTCGTGAACAACGCGGGCACCACGCACCGCAACAAGCCCGTGCTCGACGTGACGGAAGCCGAATT CGACCGCGTGTACGCGGTCAACATGAAGAGCCTGTTCTGGTGCGTGCAGACTTTCGTGCCGTACTTCCGCGCACAGGGCG GCGGCGTGTTCGTGAACGTCGCATCGACGGCCGGCGTGCGCCCGCGCCCGGGCCTCGTCTGGTACAACAGCACGAAGGGC GCGATGATCACCGCCAGCAAGTCGCTCGCGGCCGAGCTCGGCGCCGACCGTATCCGCGTGAACTGCATCAACCCGGTGCT CGGCGAAACCGCGCTGATGACCGAGTTCATGGGCTGCGAGGACACCCCGGACAATCGCCGCCGCTTCCTCGCGACGATCC CGCTCGGCCGCTTCTCGACGCCGCAGGACATCGCGAACGCCGCGCTTTATCTTGCATCCGACGAAGCCGAATTCATCACC GGCGTCTGCCTCGAAGTCGACGGCGGGCGCTGCATCTAG
Upstream 100 bases:
>100_bases ATCCGGCACGGCTGAGCGCACGGCACGCGACAGGCAGCCGGCAGCGGCCGGCAGCCCGTCGACACGCGACGATCCTCGTC ACCAGCACAGGAGACACACC
Downstream 100 bases:
>100_bases TCGTACCGGGCCGCACGATCGGCCCGTCTTGCTTCGCACGAAACCGGATCGGGCACCACCACGCCTGCTCCGGCCCACTA CAACGACAGCGGTGCATCGG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALAGGKAIAVAGDVSKEDDWRALLQAALEDF HAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFWCVQTFVPYFRAQGGGVFVNVASTAGVRPRPGLVWYNSTKG AMITASKSLAAELGADRIRVNCINPVLGETALMTEFMGCEDTPDNRRRFLATIPLGRFSTPQDIANAALYLASDEAEFIT GVCLEVDGGRCI
Sequences:
>Translated_252_residues MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALAGGKAIAVAGDVSKEDDWRALLQAALEDF HAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFWCVQTFVPYFRAQGGGVFVNVASTAGVRPRPGLVWYNSTKG AMITASKSLAAELGADRIRVNCINPVLGETALMTEFMGCEDTPDNRRRFLATIPLGRFSTPQDIANAALYLASDEAEFIT GVCLEVDGGRCI >Mature_252_residues MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALAGGKAIAVAGDVSKEDDWRALLQAALEDF HAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFWCVQTFVPYFRAQGGGVFVNVASTAGVRPRPGLVWYNSTKG AMITASKSLAAELGADRIRVNCINPVLGETALMTEFMGCEDTPDNRRRFLATIPLGRFSTPQDIANAALYLASDEAEFIT GVCLEVDGGRCI
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=31.6, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=34.136546184739, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=33.6, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=31.3253012048193, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=28.8537549407115, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=31.0077519379845, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=30.6122448979592, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI33667109, Length=228, Percent_Identity=31.140350877193, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=30.8695652173913, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=28.0155642023346, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=32.2916666666667, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=29.3172690763052, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4504505, Length=210, Percent_Identity=30, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=30.4123711340206, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI142976729, Length=186, Percent_Identity=27.9569892473118, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=27.4193548387097, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40807363, Length=201, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI31542939, Length=252, Percent_Identity=25, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4557649, Length=202, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI40254986, Length=163, Percent_Identity=26.9938650306748, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI302344755, Length=102, Percent_Identity=35.2941176470588, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI310128830, Length=240, Percent_Identity=27.9166666666667, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI310115468, Length=240, Percent_Identity=27.9166666666667, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=28.0769230769231, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI25282469, Length=225, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=39.3574297188755, Blast_Score=151, Evalue=4e-38, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=33.59375, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=32.6612903225806, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.4677419354839, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=33.4661354581673, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=30.3149606299213, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=32.03125, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=27.5590551181102, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=30.6201550387597, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=29.4354838709677, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=26.8199233716475, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=25.5905511811024, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=25.1101321585903, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=30.9236947791165, Blast_Score=127, Evalue=5e-30, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=32.8, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=35.8870967741936, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=34.9397590361446, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=30.3643724696356, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=30.5147058823529, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=32, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=36.0406091370558, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=29.0441176470588, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=31.6205533596838, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=29.5880149812734, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.5454545454545, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=28.7878787878788, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.3030303030303, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=29.277566539924, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17564282, Length=175, Percent_Identity=32.5714285714286, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=28.5185185185185, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=28.3018867924528, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17508895, Length=171, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=27.8195488721804, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=28.996282527881, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=27.4436090225564, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=27.0676691729323, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=27.1698113207547, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=27.4074074074074, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=25.2830188679245, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=29.9610894941634, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=24.812030075188, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=28.4210526315789, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI71982365, Length=200, Percent_Identity=26, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=26.6409266409266, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=22.4489795918367, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=2e-19, Organism=Saccharomyces cerevisiae, GI6323882, Length=242, Percent_Identity=26.4462809917355, Blast_Score=70, Evalue=3e-13, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=34.9206349206349, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=33.59375, Blast_Score=128, Evalue=3e-30, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=33.8645418326693, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=34.1269841269841, Blast_Score=120, Evalue=8e-28, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=33.7301587301587, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=30.241935483871, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=33.0677290836653, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=33.5051546391753, Blast_Score=98, Evalue=4e-21, Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=33.502538071066, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=31.4432989690722, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=31.9066147859922, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=30.8510638297872, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=31.7647058823529, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357673, Length=217, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI21355631, Length=194, Percent_Identity=31.4432989690722, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI161076933, Length=182, Percent_Identity=28.021978021978, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24584748, Length=182, Percent_Identity=28.021978021978, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=29.0816326530612, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24640442, Length=186, Percent_Identity=31.1827956989247, Blast_Score=64, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26736; Mature: 26736
Theoretical pI: Translated: 5.12; Mature: 5.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALAGGKAIAVA CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEE GDVSKEDDWRALLQAALEDFHAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFW CCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCEEEECCCCCCEEEEECHHHHHH CVQTFVPYFRAQGGGVFVNVASTAGVRPRPGLVWYNSTKGAMITASKSLAAELGADRIRV HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECHHHHHHCCCCEEEE NCINPVLGETALMTEFMGCEDTPDNRRRFLATIPLGRFSTPQDIANAALYLASDEAEFIT EECCCHHCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHEEEEEECCCCCEEE GVCLEVDGGRCI EEEEEECCCCCC >Mature Secondary Structure MRLSGKTAIVTGGGSGFGEGIAKTYAREGANVVVNDLNGAAAERVASEIALAGGKAIAVA CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEE GDVSKEDDWRALLQAALEDFHAVQIVVNNAGTTHRNKPVLDVTEAEFDRVYAVNMKSLFW CCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCEEEECCCCCCEEEEECHHHHHH CVQTFVPYFRAQGGGVFVNVASTAGVRPRPGLVWYNSTKGAMITASKSLAAELGADRIRV HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECHHHHHHCCCCEEEE NCINPVLGETALMTEFMGCEDTPDNRRRFLATIPLGRFSTPQDIANAALYLASDEAEFIT EECCCHHCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHEEEEEECCCCCEEE GVCLEVDGGRCI EEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9784136 [H]