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The map label for this gene is ttuB [H]

Identifier: 116690440

GI number: 116690440

Start: 2683955

End: 2685259

Strand: Direct

Name: ttuB [H]

Synonym: Bcen2424_2420

Alternate gene names: 116690440

Gene position: 2683955-2685259 (Clockwise)

Preceding gene: 116690439

Following gene: 116690441

Centisome position: 77.04

GC content: 66.74

Gene sequence:

>1305_bases
ATGGCAACATCGACGCAGTCGCTGCCGGGCTCGTCCGGCGCATTCGAGGAAGCAACCTACCGCAAGGTGTCGTGGCGGCT
CGTGCCGCTCCTCCTGCTGTGCTACGTGGTCGCGTATCTCGACCGCGTGAACGTCGGGTTCGCGAAGCTGCAGATGGCGA
GCGACCTGAACCTGAGCGATACCGTGTACGGGCTCGGCGCCGGGATCTTCTTCTTCGGCTATTTCCTGTTCGAGGTGCCG
AGCAACATCATCCTGCACCGGGTGGGCGCCCGCGTGTGGATCGCCCGCATCATGGCGACATGGGGCGTGATCTCGATCCT
GACGATGTTCGTCACGACGCCCGCGATGTTCTACGTGATGCGCTTCCTGCTCGGCGTCGCCGAAGCGGGCTTCTTCCCCG
GCGTGATCCTCTACCTCACCTACTGGTATCCCGCGCACCGGCGCGGCCGGATGACGACGTTCTTCATGACGGCCGTCGCG
CTGTCCGGCGTGATCGGCGGGCCGATCTCGGGCTTCATCCTGAAGGCGTTCGACGGCGTGAGCGGCTGGCACGGCTGGCA
ATGGCTGTTCCTGCTCGAAGGCATTCCGTCGGTGCTCGCCGGCGTGCTCGTGTTCTTCACCCTCGACGAGCGGATCGCGA
AGGCGACGTGGCTGACCGACGAAGAAAAGGCGCTGCTCGCCCGCAACGTCGACGCGGAGGAAGCCACCAAGGAGGACCTG
CCGCTCGGCGCCGTGATGTCGAGCCCGCGCGTCTGGCTGATGGCGCTGATCTATTTCTCGTTCGTGATGGGGCTCTACGG
CGTCGGCTTCTGGCTGCCGACGATCATCAAGGCGACCGGCGTGACCGACACGTTCATGATCGGCCTGCTGTCGGCGATTC
CGTATGCGGCCGCGGTGGTCGCGATGATCCTGATCGCGCGCAGCGCGGACAAGCGCCGCGAACGCCGCTGGCACCTCGCG
ATTCCGGCCGCGATCGGCGCGGTCGGCCTCGTGCTGTCGGTGATCTGGGCGCACCAGACGGCGCTCGCGATGCTCGGCCT
CACGCTCGCGACGATCGGCATCCTGACGACGCTGCCGCTGTTCTGGAGCCTGCCGACCGCGTTCCTCGGCGGCACGGCCG
CCGCCGCCGGCATCGCGATGATCAACTCGATCGGCAACCTCGCCGGCTTCCTGAGCCCGTACCTGATGGGCTGGCTCAAG
CAGGTGACGGGCACCAACGATGCGGGCATGTACATGCTGGCCGGGTTCCTCGTGCTCGGCGGGCTACTGGCGCTGTCGGT
GCCGAAGCGGCTCGTCGACAAGTGA

Upstream 100 bases:

>100_bases
ATCGGATCGAGGTAGCCGCCCAAGCGCCGACCTCGATCGACCGCAAAGCATGGGACTCAGGTAACCGCTAAAGCGCTAAC
CTGGATCGACAGGAGACAAC

Downstream 100 bases:

>100_bases
CGACGCGCGGCGCGTAAAGGCGCGCCCGGATCGATCGAACACGCCGGCCGATTCCCGGCCCGTTTCTCCCCGATACGCCC
CGACGTCCGGCATGGCCGGT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVP
SNIILHRVGARVWIARIMATWGVISILTMFVTTPAMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVA
LSGVIGGPISGFILKAFDGVSGWHGWQWLFLLEGIPSVLAGVLVFFTLDERIAKATWLTDEEKALLARNVDAEEATKEDL
PLGAVMSSPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTFMIGLLSAIPYAAAVVAMILIARSADKRRERRWHLA
IPAAIGAVGLVLSVIWAHQTALAMLGLTLATIGILTTLPLFWSLPTAFLGGTAAAAGIAMINSIGNLAGFLSPYLMGWLK
QVTGTNDAGMYMLAGFLVLGGLLALSVPKRLVDK

Sequences:

>Translated_434_residues
MATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVP
SNIILHRVGARVWIARIMATWGVISILTMFVTTPAMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVA
LSGVIGGPISGFILKAFDGVSGWHGWQWLFLLEGIPSVLAGVLVFFTLDERIAKATWLTDEEKALLARNVDAEEATKEDL
PLGAVMSSPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTFMIGLLSAIPYAAAVVAMILIARSADKRRERRWHLA
IPAAIGAVGLVLSVIWAHQTALAMLGLTLATIGILTTLPLFWSLPTAFLGGTAAAAGIAMINSIGNLAGFLSPYLMGWLK
QVTGTNDAGMYMLAGFLVLGGLLALSVPKRLVDK
>Mature_433_residues
ATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVPS
NIILHRVGARVWIARIMATWGVISILTMFVTTPAMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVAL
SGVIGGPISGFILKAFDGVSGWHGWQWLFLLEGIPSVLAGVLVFFTLDERIAKATWLTDEEKALLARNVDAEEATKEDLP
LGAVMSSPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTFMIGLLSAIPYAAAVVAMILIARSADKRRERRWHLAI
PAAIGAVGLVLSVIWAHQTALAMLGLTLATIGILTTLPLFWSLPTAFLGGTAAAAGIAMINSIGNLAGFLSPYLMGWLKQ
VTGTNDAGMYMLAGFLVLGGLLALSVPKRLVDK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=259, Percent_Identity=22.7799227799228, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87082071, Length=413, Percent_Identity=37.772397094431, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI2367379, Length=302, Percent_Identity=25.1655629139073, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=21.9512195121951, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789515, Length=417, Percent_Identity=22.3021582733813, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=292, Percent_Identity=26.027397260274, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322025, Length=320, Percent_Identity=24.0625, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324410, Length=162, Percent_Identity=27.1604938271605, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=326, Percent_Identity=23.3128834355828, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=213, Percent_Identity=23.0046948356808, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=225, Percent_Identity=23.5555555555556, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321502, Length=351, Percent_Identity=23.3618233618234, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=333, Percent_Identity=25.2252252252252, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584153, Length=355, Percent_Identity=22.8169014084507, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24655271, Length=435, Percent_Identity=23.9080459770115, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20130135, Length=435, Percent_Identity=23.9080459770115, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654215, Length=346, Percent_Identity=23.6994219653179, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19922400, Length=346, Percent_Identity=23.6994219653179, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653727, Length=405, Percent_Identity=20.4938271604938, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47157; Mature: 47025

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHH
TVYGLGAGIFFFGYFLFEVPSNIILHRVGARVWIARIMATWGVISILTMFVTTPAMFYVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVALSGVIGGPISGFILKAFDGV
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
SGWHGWQWLFLLEGIPSVLAGVLVFFTLDERIAKATWLTDEEKALLARNVDAEEATKEDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCC
PLGAVMSSPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTFMIGLLSAIPYAAAVV
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AMILIARSADKRRERRWHLAIPAAIGAVGLVLSVIWAHQTALAMLGLTLATIGILTTLPL
HHHHHHHCHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWSLPTAFLGGTAAAAGIAMINSIGNLAGFLSPYLMGWLKQVTGTNDAGMYMLAGFLVLG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLLALSVPKRLVDK
HHHHHHHHHHHHCC
>Mature Secondary Structure 
ATSTQSLPGSSGAFEEATYRKVSWRLVPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHH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HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]