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The map label for this gene is yciR [C]

Identifier: 116690374

GI number: 116690374

Start: 2615803

End: 2618175

Strand: Direct

Name: yciR [C]

Synonym: Bcen2424_2354

Alternate gene names: 116690374

Gene position: 2615803-2618175 (Clockwise)

Preceding gene: 116690373

Following gene: 116690375

Centisome position: 75.08

GC content: 66.16

Gene sequence:

>2373_bases
ATGGCGCACGCGAGCAGGACGCCGCCCTCTTCGATGAGCTCTGCCCGGTCCAACCACACGCCGCCGAACCGGCCGCTGCG
CGCGCCGCGCAAGTCGCGCCGGCGTGCGCTGTTCGCCATCCCGCTGCTCGGGATGCTGGCGCTCGCGCTGCTGTGGGCCG
TGATCATCGCGCGTCTGTCCGTCGAAAAGGACAGTGCGTACAAGGAAGCGGCGGCCTCCGCGGCGATCCTGTCGTCCGCG
CTCGAGCAGCATACGGTCAAGGCGATCCACCAAGTCGACCAGATCACCCGCTTCGTCAAGTTCGAATTCGAGAAATCGCC
GGCGCGCTTCAATCTCGCGAGCGCCGTCGAGAAAGGCGTCGTGCCGAGCGACACGCTGATCCAGGTATCGCTCGTCAACG
CGAAGGGCATCCTGTTCGCGAACACCGCCGAACTCCATCCGCAGCCGATCAACCTGTCCGACCGCGAGCACTTCAAGGTC
CACCTCGCGCACAACGACGACCGCCTCTTCATCAGCAAGCCCGTGCTCGGCCGCGTGTCGAGCCACTGGACGCTGCAGAT
GACGCGGCGCCTGAACAACCCGGACGGCAGCTTCGCGGGCATCGTCGTGGTGTCGGAAGACCCGAGCTACTTCACGAACG
ATTTCTACAACAACGCGGCCATCGGCAAGGAAGGCGTGATCGCGGTCGTGTCCGATACGGGCGCAGTGCTCGCGCGGCGC
ACAGGCTCGGTGAGCAACGCGCCGGGCGCGTTTTCGGCGTCGGGCGTCTACCCGATCGCCGAGCGCGTGACGGGCACGAT
CATCGATCCGATCGACGGCGTGACGCGCATCGTGTCGTACCGCCACCTCGACGGCTACCCGCTCGCGGTGATGGTCGGCC
TGTCGCAGACGGAAGAGTTCGCGGACTACACCCACACGCGCAACGTCTACCTGCTGATGACGAGCTTCATCACGCTCGCG
ATGCTCGCGTTTTTCGGCGTCGCGACGGGCCTGATCGGCAAGCTGCTCGGCCGCGAGCGCGAAATGACGCAGCTCGCCGA
ATACGACCTGCTCACCGGCCTCGCGAACCGCTATGCGACGCTGCGCGGGCTGCGCAACGACGTGTCGATGCCCGCGAGCC
TGTCGCGGCTCGGCCTGCTGTTCATCGATCTCGACAACTTCAAGACCGTCAACGACACGCTCGGCCACAACGCCGGCGAC
ATCGTGCTGCAGATGACCGCGTCGCGCCTGGCCGATGCGGTCGGCGACGAAGGTTCGCTCGCGCGCATCGGCGGCGACGA
GTTCGTCGTCGTGATGAAGGGCGACGACGTCGAGCGGCGCGCGGTGCGGCTCGCGGAAGCGATCATCCGGATGTTCGGCG
AGCCGTTCGACGTGCGCGGCAGTTCGTTCGTGCTGCATGCGAGCATCGGCATCGCGCTGCACACCGTCGCGAACGAAAGC
GAGATCGACCTGCTGAAAAAGGCCGACCTCGCGATGTACAGCGCGAAGGACGCCGGCAAGAACTGCTACCAGTTCTATGC
GCCGCACCTGTCGCACCGGGCCGACCATCTGATGCGCTGGGAACAGCAATTGCGCGTCGCGCTCGCCGAGGGGCAGTTGT
TCCTCGCGTACCAGCCGAAGATCGACCTCACGCATCGCACCATCACCGGCTTCGAGGCGCTCGCACGCTGGGATCACCCC
GAGCACGGCGTCATCTCCGCGAACGAATTCATTTCGATCGCCGAATCGACCGGCCTGATCGTGCCGATCGGCGACTTCGT
GATCCGCACCGCGTGCGAGCAGATCGCGCGCTGGCGCGACGAAGGCCACGACACGCTGACGCTCGCGGTCAACATCTCGC
CCGTGCAGTTCTGGCGCGGCGACCTGATCGAGACGATCTCGCAGGCGCTGCAGGACACCGGCATCCCCGCGAACCGGCTC
GAGATCGAGATCACCGAGACCGCGATGATGGAATATCCGGAACTCGTGTCCGAGAAGATCGTCGCGCTGAAAAAGCTCGG
CATCCGGATCGCGCTCGACGATTTCGGCACCGGCTATTCATCGCTGTCGTACCTGCACCGCTTCTCCGTCGATACGCTGA
AGGTCGACCGCTCGTTCGTGCAGGCGATTCCGAACGACCGCAGCGTGTGCGTGATGGTGTCGTCGATCGTGCATCTCGCG
CGCTCGCTCGGGCTGACGGTCGTCGTCGAGGGCACCGAGACCGAGGAGCAGATCACGTGGCTGTCCGCGCTCGGCGAAAT
CGAGGCGCAGGGCTTCCTGTTCTCGCGCCCGGTGCCGGCCGATGCGATTCCCGCGCTGATCGCCCGCTTCGGCGTGCGCG
GCGAGCATCCGAATGTCGTCGCGCATCGCGCGACCGGCAGCACGGGCGCCTGA

Upstream 100 bases:

>100_bases
TCGGGCCTAATCCGTTGTTTCGGAGGTCTGTCCATGGTTGCGCGTCCCGCGAACGAACAGACGTCGGGACAATCCGAACC
ATAGCCGGCCATCCAGACGG

Downstream 100 bases:

>100_bases
GCGCCGCCCTGCTGCAGGCGCGCGCGTTGTGCGACGCCGCAATTATTTCGTTTTCCGATCCGATCGTTCAATTCATTAAC
TAGCGTTTTCGCGCATGGCA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MAHASRTPPSSMSSARSNHTPPNRPLRAPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAASAAILSSA
LEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGVVPSDTLIQVSLVNAKGILFANTAELHPQPINLSDREHFKV
HLAHNDDRLFISKPVLGRVSSHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARR
TGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEFADYTHTRNVYLLMTSFITLA
MLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPASLSRLGLLFIDLDNFKTVNDTLGHNAGD
IVLQMTASRLADAVGDEGSLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRGSSFVLHASIGIALHTVANES
EIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLTHRTITGFEALARWDHP
EHGVISANEFISIAESTGLIVPIGDFVIRTACEQIARWRDEGHDTLTLAVNISPVQFWRGDLIETISQALQDTGIPANRL
EIEITETAMMEYPELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPNDRSVCVMVSSIVHLA
RSLGLTVVVEGTETEEQITWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGEHPNVVAHRATGSTGA

Sequences:

>Translated_790_residues
MAHASRTPPSSMSSARSNHTPPNRPLRAPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAASAAILSSA
LEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGVVPSDTLIQVSLVNAKGILFANTAELHPQPINLSDREHFKV
HLAHNDDRLFISKPVLGRVSSHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARR
TGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEFADYTHTRNVYLLMTSFITLA
MLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPASLSRLGLLFIDLDNFKTVNDTLGHNAGD
IVLQMTASRLADAVGDEGSLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRGSSFVLHASIGIALHTVANES
EIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLTHRTITGFEALARWDHP
EHGVISANEFISIAESTGLIVPIGDFVIRTACEQIARWRDEGHDTLTLAVNISPVQFWRGDLIETISQALQDTGIPANRL
EIEITETAMMEYPELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPNDRSVCVMVSSIVHLA
RSLGLTVVVEGTETEEQITWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGEHPNVVAHRATGSTGA
>Mature_789_residues
AHASRTPPSSMSSARSNHTPPNRPLRAPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAASAAILSSAL
EQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGVVPSDTLIQVSLVNAKGILFANTAELHPQPINLSDREHFKVH
LAHNDDRLFISKPVLGRVSSHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARRT
GSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEFADYTHTRNVYLLMTSFITLAM
LAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPASLSRLGLLFIDLDNFKTVNDTLGHNAGDI
VLQMTASRLADAVGDEGSLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRGSSFVLHASIGIALHTVANESE
IDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLTHRTITGFEALARWDHPE
HGVISANEFISIAESTGLIVPIGDFVIRTACEQIARWRDEGHDTLTLAVNISPVQFWRGDLIETISQALQDTGIPANRLE
IEITETAMMEYPELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPNDRSVCVMVSSIVHLAR
SLGLTVVVEGTETEEQITWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGEHPNVVAHRATGSTGA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=432, Percent_Identity=37.037037037037, Blast_Score=264, Evalue=2e-71,
Organism=Escherichia coli, GI87081921, Length=429, Percent_Identity=33.5664335664336, Blast_Score=235, Evalue=7e-63,
Organism=Escherichia coli, GI226510982, Length=387, Percent_Identity=29.4573643410853, Blast_Score=185, Evalue=1e-47,
Organism=Escherichia coli, GI1787055, Length=429, Percent_Identity=27.972027972028, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1790496, Length=264, Percent_Identity=34.0909090909091, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788502, Length=250, Percent_Identity=37.6, Blast_Score=152, Evalue=9e-38,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=32.7731092436975, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=32.5396825396825, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=34.2857142857143, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1786507, Length=240, Percent_Identity=32.5, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=32.0987654320988, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788381, Length=396, Percent_Identity=25.2525252525253, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=37.1951219512195, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082096, Length=237, Percent_Identity=29.957805907173, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786584, Length=198, Percent_Identity=31.3131313131313, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081977, Length=201, Percent_Identity=31.8407960199005, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=30.6748466257669, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082007, Length=233, Percent_Identity=26.1802575107296, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=33.1325301204819, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=35.0877192982456, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=29.7619047619048, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787262, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787410, Length=235, Percent_Identity=22.9787234042553, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 86467; Mature: 86336

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHASRTPPSSMSSARSNHTPPNRPLRAPRKSRRRALFAIPLLGMLALALLWAVIIARLS
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHC
VEKDSAYKEAAASAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHCC
VPSDTLIQVSLVNAKGILFANTAELHPQPINLSDREHFKVHLAHNDDRLFISKPVLGRVS
CCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCHHHCCC
SHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARR
CCEEEEEEHHCCCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEHCC
TGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEF
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
ADYTHTRNVYLLMTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYAT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LRGLRNDVSMPASLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLADAVGDEGSL
HHHHHHCCCCCCHHHHCEEEEEECCCCCCHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCE
ARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRGSSFVLHASIGIALHTVANES
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEECCCC
EIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPK
HHHHHHHHHHHHEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IDLTHRTITGFEALARWDHPEHGVISANEFISIAESTGLIVPIGDFVIRTACEQIARWRD
CCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHH
EGHDTLTLAVNISPVQFWRGDLIETISQALQDTGIPANRLEIEITETAMMEYPELVSEKI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHH
VALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPNDRSVCVMVSSIVHLA
HHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RSLGLTVVVEGTETEEQITWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGEHPNVV
HHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEE
AHRATGSTGA
EEECCCCCCC
>Mature Secondary Structure 
AHASRTPPSSMSSARSNHTPPNRPLRAPRKSRRRALFAIPLLGMLALALLWAVIIARLS
CCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHC
VEKDSAYKEAAASAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPARFNLASAVEKGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHCC
VPSDTLIQVSLVNAKGILFANTAELHPQPINLSDREHFKVHLAHNDDRLFISKPVLGRVS
CCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCHHHCCC
SHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARR
CCEEEEEEHHCCCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEHCC
TGSVSNAPGAFSASGVYPIAERVTGTIIDPIDGVTRIVSYRHLDGYPLAVMVGLSQTEEF
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
ADYTHTRNVYLLMTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYAT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LRGLRNDVSMPASLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLADAVGDEGSL
HHHHHHCCCCCCHHHHCEEEEEECCCCCCHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCE
ARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFGEPFDVRGSSFVLHASIGIALHTVANES
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEECCCC
EIDLLKKADLAMYSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPK
HHHHHHHHHHHHEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IDLTHRTITGFEALARWDHPEHGVISANEFISIAESTGLIVPIGDFVIRTACEQIARWRD
CCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHH
EGHDTLTLAVNISPVQFWRGDLIETISQALQDTGIPANRLEIEITETAMMEYPELVSEKI
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHH
VALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPNDRSVCVMVSSIVHLA
HHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RSLGLTVVVEGTETEEQITWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGEHPNVV
HHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCEE
AHRATGSTGA
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]