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The map label for this gene is fabZ [H]

Identifier: 116690029

GI number: 116690029

Start: 2224173

End: 2224640

Strand: Reverse

Name: fabZ [H]

Synonym: Bcen2424_2008

Alternate gene names: 116690029

Gene position: 2224640-2224173 (Counterclockwise)

Preceding gene: 116690030

Following gene: 116690028

Centisome position: 63.85

GC content: 62.39

Gene sequence:

>468_bases
ATGAGCACTGAAAAAATCAATCTCGACATCCACAAGATCCTCACGCTGCTGCCGCATCGCTACCCGATTCTGCTCGTCGA
TCGCGTGCTCGAACTCGAGCCGCACAAAGGGATCAAAGCGCTGAAGAACGTGTCGATCAACGAGCCGTTCTTCCAGGGGC
ATTTCCCGAAGCGGCCGGTGATGCCGGGTGTGCTGATCCTCGAGGCGCTCGCCCAGGCCGCGGCGCTGCTGACGTTCGCG
GAAGAGCAGCCGAAGGACCCGGAGAACACGCTGTATTACTTCGTCGGGATCGACGGCGCGCGCTTCAAGCGCGTGGTCGA
ACCGGGCGACCAGCTGATCCTGAACGTGACGTTCGAGCGCTACATCCGCGGCATCTGGAAGTTCAAGGCGGTGGCGGAAG
TGGACGGCAAGGTGGCGGCGGAAGCCGAACTGATGTGCACGGTCAAGACGGCCGACGCGGCGCCCTGA

Upstream 100 bases:

>100_bases
CGGCCAGCGCAACCGGCCCGGTTTGCCAGACGGGGCCGCGCGGCGGCCCGCTTCAGCCTTTGCATCACCACCGCGCAGCC
TCTGCGTGAGACGAACCATC

Downstream 100 bases:

>100_bases
GCGACGCGGCACGCATGGGTAACATCACGCGAACAACGCGACACATCATATCGAGAGGCAACGGCGCATGACCAGGATTC
ATCCTACCGCGATCGTCGAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPFFQGHFPKRPVMPGVLILEALAQAAALLTFA
EEQPKDPENTLYYFVGIDGARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP

Sequences:

>Translated_155_residues
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPFFQGHFPKRPVMPGVLILEALAQAAALLTFA
EEQPKDPENTLYYFVGIDGARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
>Mature_154_residues
STEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPFFQGHFPKRPVMPGVLILEALAQAAALLTFAE
EQPKDPENTLYYFVGIDGARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=59.5890410958904, Blast_Score=179, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17393; Mature: 17261

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPFFQGHFPKRPV
CCCCEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCC
MPGVLILEALAQAAALLTFAEEQPKDPENTLYYFVGIDGARFKRVVEPGDQLILNVTFER
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEEHHH
YIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
HHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC
>Mature Secondary Structure 
STEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPFFQGHFPKRPV
CCCEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCC
MPGVLILEALAQAAALLTFAEEQPKDPENTLYYFVGIDGARFKRVVEPGDQLILNVTFER
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEEEHHH
YIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
HHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA