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The map label for this gene is atzB [H]

Identifier: 116689977

GI number: 116689977

Start: 2174741

End: 2176153

Strand: Reverse

Name: atzB [H]

Synonym: Bcen2424_1956

Alternate gene names: 116689977

Gene position: 2176153-2174741 (Counterclockwise)

Preceding gene: 116689980

Following gene: 116689974

Centisome position: 62.46

GC content: 69.85

Gene sequence:

>1413_bases
ATGAATCTCGAGCAGCACGCTGGCGCACGCGCGCCGAACCCTTCCTCATCCCGCCCGAAAACCCTGCTGGTCAAGCACGC
CGACGTGCTCGTGACCATGGACGACACGCGCCGCGAGCTGCGCGACGCGGGGCTCTACATCGAAGACAACCGGATCGTCG
CGGTCGGCCCGAGCGCCGAGCTGCCCGACACGGCCGACGAAGTGCTCGACCTGCGCGGCCACCTGGTGATCCCGGGGCTC
GTGAACACGCACCACCACATGTACCAGAGCCTCACGCGCGCGGTGCCGGCCGCGCAGAACGCCGAGCTGTTCGGCTGGCT
CACGAACCTCTACCGGATCTGGGCGCACCTGAGCCCCGAGATGATCGAGGTGTCGACGCTCACCGCGATGGCCGAGCTGC
TGCAGTCGGGCTGCACGACGTCGAGCGATCATCTGTACATCTACCCGAACGGCAGCCGGCTCGACGACAGCATCGGCGCC
GCGCAGCGGATCGGCATGCGCTTTCACGCGAGCCGCGGCGCGATGAGCGTCGGCCAGCGCGACGGCGGGCTGCCGCCCGA
TTCGGTCGTCGAGCGCGAACCCGACATCCTGCGCGACGCGCAGCGCCTGATCGAGACCTATCACGACGAAGGCCGCTACG
CGATGCTGCGCGTGGTGGTCGCGCCGTGCTCGCCGTTCTCGGTGAGCCGCGAGCTGATGCGCGACGCGGCCGTGCTCGCG
CGCGAATACGGCGTGTCGCTGCATACGCACCTCGCGGAGAACGTCAACGACATTGCGTACAGCCGCGAGAAGTTCGGGAT
GACGCCCGCCGAATATGCGGAAGATCTCGGCTGGGTCGGCCACGACGTGTGGCACGCGCACTGCGTGCAGCTCGACGATG
CGGGCATCGGCCTGTTTGCACGCACCGGCACGGGCGTCGCGCATTGCCCGTGCTCGAACATGCGCCTGGCGTCAGGCATC
GCGCCGGTGAAGAAGATGCGGCTCGCGGGCGTGCCGGTCGGCCTCGGCGTCGACGGTTCCGCGTCGAACGACGGCGCGCA
GATGGTGGCCGAGGTACGCCAGGCGCTGCTGCTGCAGCGGGTCGGCTTCGGGCCCGACGCGATGACCGCGCGCGAAGCGC
TCGAGATCGCGACGCTCGGCGGTGCGAAGGTGCTGAACCGCGACGACATCGGCGCGCTGAAGCCCGGCATGGCGGCGGAT
TTCGCCGCGTTCGACCTGCGTCAGCCGCTGTTCGCGGGCGCGCTGCACGATCCGGTCGCGGCGCTCGTGTTCTGCGCGCC
GTCGCAGACGGCGTACACGGTGGTGAACGGGAAGGTGGTGGTGCGGGAAGGGCGGCTCGCGACGCTCGATTTGCCGCCGG
TGATCGAGCGTCACAACGCGCTGGCGCAGGCGCTCGTGGAAGCGTCGCGCTGA

Upstream 100 bases:

>100_bases
GAACGGACGCAGGCACCGGGGCGTGCCGCGATTCAGCGTTCGAACGGCAGTGTGACCGCTTCCAGGGCAGCCCCTGGAGG
CAGACCGACGCGGAGAACGC

Downstream 100 bases:

>100_bases
CGCGTCGGCGGGGAGGTCGCGCAGCACGTTGCGCAGCGGGGCGCGGCCATTGTGGCCACCACCCGTCGCGCAACGCGCCG
TGGTCGCGCGTAACGGCGCG

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNLEQHAGARAPNPSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWAHLSPEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRELMRDAAVLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAQALVEASR

Sequences:

>Translated_470_residues
MNLEQHAGARAPNPSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWAHLSPEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRELMRDAAVLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAQALVEASR
>Mature_470_residues
MNLEQHAGARAPNPSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWAHLSPEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRELMRDAAVLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAQALVEASR

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=382, Percent_Identity=24.0837696335079, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789249, Length=440, Percent_Identity=29.7727272727273, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082177, Length=425, Percent_Identity=25.4117647058824, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540282, Length=404, Percent_Identity=23.2673267326733, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319963, Length=345, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643849, Length=357, Percent_Identity=24.9299719887955, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50729; Mature: 50729

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEQHAGARAPNPSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAE
CCCCHHCCCCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHCCCEEECCEEEEECCCCC
LPDTADEVLDLRGHLVIPGLVNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWAHLSPE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCH
MIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGAAQRIGMRFHASRGAMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCHHEECCCCCHHCCCC
DGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRELMRDAAVLA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHEEEEECCCCCEEEE
RTGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAADFAAFDLRQPLFAGALHDPVA
CCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHE
ALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAQALVEASR
EHEEECCCCCEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLEQHAGARAPNPSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAE
CCCCHHCCCCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHCCCEEECCEEEEECCCCC
LPDTADEVLDLRGHLVIPGLVNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWAHLSPE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCH
MIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGAAQRIGMRFHASRGAMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCHHEECCCCCHHCCCC
DGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRELMRDAAVLA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHEEEEECCCCCEEEE
RTGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAADFAAFDLRQPLFAGALHDPVA
CCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHE
ALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAQALVEASR
EHEEECCCCCEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]