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The map label for this gene is ppiD [H]

Identifier: 116689941

GI number: 116689941

Start: 2131683

End: 2133620

Strand: Reverse

Name: ppiD [H]

Synonym: Bcen2424_1920

Alternate gene names: 116689941

Gene position: 2133620-2131683 (Counterclockwise)

Preceding gene: 116689942

Following gene: 116689939

Centisome position: 61.24

GC content: 65.07

Gene sequence:

>1938_bases
ATGCTCGATTTCTTCCGTAATCACCAGCGCCTGATGATGGCGCTCCTGCTCCTGATCGTGTTGCCGGGGCTGGGTTTCGT
CGGGATCCAAGGTTTCCGCGGTTTCTTCGACGACAGTGCGAACGTCGCGGCAGTCAACGGGCACAAGATCACGCGGGTCG
AATTCGACGGCGCGTTCCGTCAACAGATCGATCAGGCGCGTCAGGCGCTCGGCGGGCAGTTCGACATCAAGATGTTCGAC
ACGCCCGAGCATCGCAAGCAGGTGCTCGACGGGCTGATCCAGCAACGCGTGCTGGCCGACGAGACGCAACGTCTGCACCT
GACGGCCTCCGACAACGCCGTGCGCGATGCGCTGATGAGCGACCCGATGATCGCGTCGCTGAAGAAGCCCGACGGCACGA
TCGACGTCGAACGCTATGCGCAGCTGCTGTCGTTCCAGGGGATGACGCCCGAGCAGTACCAGGAACGGGTGCGTTACAGC
CTGTCGCTGCAGCAGATTCCGGCCAGCATCGTGTCGAGCGCGTTCACGCCGAAGAGCCTCGCGCAACACCTGTCCGAACT
CGCCGCGCAGCAGCGTGAAGTGCAGGCGCTCGTGCTGAAGACGAGCGACTTCGCAGCGAAGGTCCAGCCGACCGACGCGC
AGCTCACCGCGTACTACGACGCGCACAAGCAGAGCTTCGCGACGCCGGAAACCGCGACGATCCAGTACCTCGTCTATTCG
CCGGCCGCAGCGGCTGCGAGCGCGCAGCCGACCGAAGCGGACATCAAGAAGTTTTACGACGACAACCCGACGCACTTCCG
TACCGAAGCGCAGGTGCGCGTGAGCCACATCTTCATTGCTGCGCCGGGCAGCGCCAGCGCGGCCGACAAGGCAGCAGCAA
AGGCGAAGGCCGAGCAACTGCTCGCCGACGTGAAGGCGCATCCGGACCAGTTCGCGCAGATCGCGCAGAAGAGCTCGCAG
GATGCGCCGTCGGCGGCGAAGGGCGGCGACCTCGGCTTCATCACGCGCGGCTCGACCGCGGGCGGCAAGGCATTCGACGA
CGCCGCGTTCTCGCTCAAGCAGGGCGACGTGAGCGGTATCGTGCAGTCGGATCTCGGTTTCCACATCCTGAAGGCGACCG
AAGTGAAGCCGGCGGTCGTCAAGCCGTTCGCGGAAGTGAAGGACCAGATCGCGGTCGACCTGAAGCAGCAGTACGCATCG
AAGGCGTTCTCGGACAACGCGGAAGGCTTCACGTCGACCGTCTACGAAAAGGCGAAGACGCTGCAGCCGGCCGCGGACAA
GTACAAGCTGACGATCCAGACGGCCACCGTCACGCCGACGCCGAATCCGCAACTGCCGCCGACGAGCCCGTTGAACAATC
CGAAGTTCCTGGCCGCCGTGTTCGCGAACGACGCGGTGAAGAACCAGAACAACACGCAGGCGATCGACGTCGGCAACAAC
ACGCTGATCTCGGCGCGCGTGACCGAGCACAAGCCGGCTGCCGTGCCCGCGCTCGACGCGATCAAGGACGTCGTGCGCCA
GAAGGTCATCGCCGAGCAGGCCGCGGAACTCGCGAAGAAGGACGGTGCGGCGAAGCTGGCCGAGCTGCAGAAGTCGAAGT
CGACCGACGGGTTCGCGGCTGCGCAGAAGGTGTCGCGCACGCAATCGCAGGGCCTGACGCCGGCTGCGCTGAGCGCCGTC
TACAAGGTCGATGCGAAGACGCTGCCTGCTTACGTCGGGGTCGACCTCGGCGCGGACGGTTATGCGATCTATCGCGTGAA
CGCGGTGATCCCGGGTTCGGCGGTCGATCCGCAGCAACTGGCGGCCGCGCAGCAGCAGATGGCGCAGGTCGACGCGCAAA
GCGAAGGCGAAGCGTATCTCGCCGCGTTGCGCGATCGTTCGAAGGTCAAGCTGTACGGCAGCACGACGGCCAGCCAGCAG
CAGGACGGCGACAACTAA

Upstream 100 bases:

>100_bases
TGATTCCACTCCGCGCTCGAGCACAGCATTGCCTGCGTTTTATCCCGTCCCACCCCGTATGTTGTAATATCGGTCGTTTT
GTCCAATTTTCCCGTCACGC

Downstream 100 bases:

>100_bases
GCCTCGTTTCGCCCGCAACCATCAAAAAGCCCCGCTCGAAGCGGGGCTTTTCGTTTTGCGACGCTCGGCTGCGGTCAGCC
GCGCGGCTTGCCGAGCAACG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFRQQIDQARQALGGQFDIKMFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMSDPMIASLKKPDGTIDVERYAQLLSFQGMTPEQYQERVRYS
LSLQQIPASIVSSAFTPKSLAQHLSELAAQQREVQALVLKTSDFAAKVQPTDAQLTAYYDAHKQSFATPETATIQYLVYS
PAAAAASAQPTEADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKAAAKAKAEQLLADVKAHPDQFAQIAQKSSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFSLKQGDVSGIVQSDLGFHILKATEVKPAVVKPFAEVKDQIAVDLKQQYAS
KAFSDNAEGFTSTVYEKAKTLQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDAVKNQNNTQAIDVGNN
TLISARVTEHKPAAVPALDAIKDVVRQKVIAEQAAELAKKDGAAKLAELQKSKSTDGFAAAQKVSRTQSQGLTPAALSAV
YKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTTASQQ
QDGDN

Sequences:

>Translated_645_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFRQQIDQARQALGGQFDIKMFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMSDPMIASLKKPDGTIDVERYAQLLSFQGMTPEQYQERVRYS
LSLQQIPASIVSSAFTPKSLAQHLSELAAQQREVQALVLKTSDFAAKVQPTDAQLTAYYDAHKQSFATPETATIQYLVYS
PAAAAASAQPTEADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKAAAKAKAEQLLADVKAHPDQFAQIAQKSSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFSLKQGDVSGIVQSDLGFHILKATEVKPAVVKPFAEVKDQIAVDLKQQYAS
KAFSDNAEGFTSTVYEKAKTLQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDAVKNQNNTQAIDVGNN
TLISARVTEHKPAAVPALDAIKDVVRQKVIAEQAAELAKKDGAAKLAELQKSKSTDGFAAAQKVSRTQSQGLTPAALSAV
YKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTTASQQ
QDGDN
>Mature_645_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFRQQIDQARQALGGQFDIKMFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMSDPMIASLKKPDGTIDVERYAQLLSFQGMTPEQYQERVRYS
LSLQQIPASIVSSAFTPKSLAQHLSELAAQQREVQALVLKTSDFAAKVQPTDAQLTAYYDAHKQSFATPETATIQYLVYS
PAAAAASAQPTEADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKAAAKAKAEQLLADVKAHPDQFAQIAQKSSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFSLKQGDVSGIVQSDLGFHILKATEVKPAVVKPFAEVKDQIAVDLKQQYAS
KAFSDNAEGFTSTVYEKAKTLQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDAVKNQNNTQAIDVGNN
TLISARVTEHKPAAVPALDAIKDVVRQKVIAEQAAELAKKDGAAKLAELQKSKSTDGFAAAQKVSRTQSQGLTPAALSAV
YKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTTASQQ
QDGDN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=652, Percent_Identity=27.3006134969325, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69266; Mature: 69266

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCHHH
QQIDQARQALGGQFDIKMFDTPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMS
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHC
DPMIASLKKPDGTIDVERYAQLLSFQGMTPEQYQERVRYSLSLQQIPASIVSSAFTPKSL
CCHHHHCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AQHLSELAAQQREVQALVLKTSDFAAKVQPTDAQLTAYYDAHKQSFATPETATIQYLVYS
HHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCEEEEEEHHHHHHCCCCCCCEEEEEEEC
PAAAAASAQPTEADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKAAAKAKAEQL
CHHHHCCCCCCHHHHHHHHCCCCCEEECCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
LADVKAHPDQFAQIAQKSSQDAPSAAKGGDLGFITRGSTAGGKAFDDAAFSLKQGDVSGI
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCHHHH
VQSDLGFHILKATEVKPAVVKPFAEVKDQIAVDLKQQYASKAFSDNAEGFTSTVYEKAKT
HHHCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDAVKNQNNTQAIDVGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCEEEECCCC
TLISARVTEHKPAAVPALDAIKDVVRQKVIAEQAAELAKKDGAAKLAELQKSKSTDGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
AQKVSRTQSQGLTPAALSAVYKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQL
HHHHHHHHHCCCCHHHHHHHHHHCCHHCCCEEEEEECCCCEEEEEEEEECCCCCCCHHHH
AAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTTASQQQDGDN
HHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCHHH
QQIDQARQALGGQFDIKMFDTPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMS
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHC
DPMIASLKKPDGTIDVERYAQLLSFQGMTPEQYQERVRYSLSLQQIPASIVSSAFTPKSL
CCHHHHCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AQHLSELAAQQREVQALVLKTSDFAAKVQPTDAQLTAYYDAHKQSFATPETATIQYLVYS
HHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCEEEEEEHHHHHHCCCCCCCEEEEEEEC
PAAAAASAQPTEADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKAAAKAKAEQL
CHHHHCCCCCCHHHHHHHHCCCCCEEECCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
LADVKAHPDQFAQIAQKSSQDAPSAAKGGDLGFITRGSTAGGKAFDDAAFSLKQGDVSGI
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCHHHH
VQSDLGFHILKATEVKPAVVKPFAEVKDQIAVDLKQQYASKAFSDNAEGFTSTVYEKAKT
HHHCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDAVKNQNNTQAIDVGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCEEEECCCC
TLISARVTEHKPAAVPALDAIKDVVRQKVIAEQAAELAKKDGAAKLAELQKSKSTDGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
AQKVSRTQSQGLTPAALSAVYKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQL
HHHHHHHHHCCCCHHHHHHHHHHCCHHCCCEEEEEECCCCEEEEEEEEECCCCCCCHHHH
AAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTTASQQQDGDN
HHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]