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The map label for this gene is otsB [H]

Identifier: 116689179

GI number: 116689179

Start: 1267090

End: 1267842

Strand: Direct

Name: otsB [H]

Synonym: Bcen2424_1157

Alternate gene names: 116689179

Gene position: 1267090-1267842 (Clockwise)

Preceding gene: 116689175

Following gene: 116689180

Centisome position: 36.37

GC content: 69.19

Gene sequence:

>753_bases
ATGCAATCCGTTCCGGCTTCCCTGTCCCTGACCGATACAGCGTTCTTCTTCGACTTCGACGGCACGCTCGTCGAACTGGC
GCCGACCCCCGACGCCATTCACGTTCCGCCGTCGCTGCTGACGCTGCTCGACGAATTGTCGCGCCGCTCGCACGGCGCGG
TCGCGATCGTGTCCGGGCGCGGGATCGACAACCTCGACACGTTCCTGAAGATGCCCGGGCTGCCGATCGCCGGCCTGCAC
GGCGCGGAGCGCCGCGATGCGAACGGCGACACGCAGCGTATCGGCTTCAACGACGAACGCCTGCTGCGCATCGAGCGCGA
GCTTGCCGGCGTGGTCGACCGCCATCCGGGCATGCTGCTCGAAATCAAGGGCGCGGCCGTCGCGCTGCACTTTCGCAATG
CGCCCGAGCGCGAGGCGGTGGCGCGCGAAGCGGCCGAGCGCCTCGTCTCCGACTATGCGGATGCGTATGTGCTGCAACCC
GGCAAGATGGTGTTCGAGATCAAGCCGAAGGGCGTCGACAAGGGCCGCGCGCTGGCCGCGTTCCTCGACGAGCCGCCGTT
TGCGGGCCGCGTGCCGCTGTTCGCGGGCGACGACCTGACCGACGAGAAGGGCTTCGCGGTGGTCAACGCGCGCGGCGGCC
TGTCGATCAAGGTCGGCGCGGGCGAGACGTCCGCGCGCATGCGGCTCGATTCGGTCGACGCGCTGCATGAGCAGATCGCA
GGCTGGCTCGGTGCGGGGCAACCGCACGCATGA

Upstream 100 bases:

>100_bases
GTTTCGCCCATCTGGGGGCGCAGGCGCGGTAAGATGCGCACAACTCCATTCGCGCAGTGGCGGCCTGCGTTTGCCGGCCG
GCCCTCAGACTATCGAATCG

Downstream 100 bases:

>100_bases
GCCGGCTCATCATCGTTTCAAACCGCGTCGCGCCGATTTCGGAAGGCGAACCGGCGGCGGGCGGCCTCGCGATCGGCGTC
TATGATGCGCTGAAGGAAAC

Product: HAD family hydrolase

Products: NA

Alternate protein names: TPP; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDAIHVPPSLLTLLDELSRRSHGAVAIVSGRGIDNLDTFLKMPGLPIAGLH
GAERRDANGDTQRIGFNDERLLRIERELAGVVDRHPGMLLEIKGAAVALHFRNAPEREAVAREAAERLVSDYADAYVLQP
GKMVFEIKPKGVDKGRALAAFLDEPPFAGRVPLFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
GWLGAGQPHA

Sequences:

>Translated_250_residues
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDAIHVPPSLLTLLDELSRRSHGAVAIVSGRGIDNLDTFLKMPGLPIAGLH
GAERRDANGDTQRIGFNDERLLRIERELAGVVDRHPGMLLEIKGAAVALHFRNAPEREAVAREAAERLVSDYADAYVLQP
GKMVFEIKPKGVDKGRALAAFLDEPPFAGRVPLFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
GWLGAGQPHA
>Mature_250_residues
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDAIHVPPSLLTLLDELSRRSHGAVAIVSGRGIDNLDTFLKMPGLPIAGLH
GAERRDANGDTQRIGFNDERLLRIERELAGVVDRHPGMLLEIKGAAVALHFRNAPEREAVAREAAERLVSDYADAYVLQP
GKMVFEIKPKGVDKGRALAAFLDEPPFAGRVPLFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
GWLGAGQPHA

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=219, Percent_Identity=48.8584474885845, Blast_Score=203, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6320279, Length=223, Percent_Identity=28.6995515695067, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920676, Length=235, Percent_Identity=28.936170212766, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221473368, Length=236, Percent_Identity=27.1186440677966, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129307, Length=236, Percent_Identity=27.1186440677966, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582490, Length=236, Percent_Identity=27.1186440677966, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 26779; Mature: 26779

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDAIHVPPSLLTLLDELSRRSHGAVAIVSGR
CCCCCCCEEEECEEEEEECCCEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCEEEEECC
GIDNLDTFLKMPGLPIAGLHGAERRDANGDTQRIGFNDERLLRIERELAGVVDRHPGMLL
CCCHHHHHHHCCCCCEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEE
EIKGAAVALHFRNAPEREAVAREAAERLVSDYADAYVLQPGKMVFEIKPKGVDKGRALAA
EECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCEEEE
FLDEPPFAGRVPLFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
ECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCCHHEEHHHHHHHHHHHH
GWLGAGQPHA
HHHCCCCCCC
>Mature Secondary Structure
MQSVPASLSLTDTAFFFDFDGTLVELAPTPDAIHVPPSLLTLLDELSRRSHGAVAIVSGR
CCCCCCCEEEECEEEEEECCCEEEEEECCCCCEECCHHHHHHHHHHHHCCCCCEEEEECC
GIDNLDTFLKMPGLPIAGLHGAERRDANGDTQRIGFNDERLLRIERELAGVVDRHPGMLL
CCCHHHHHHHCCCCCEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEE
EIKGAAVALHFRNAPEREAVAREAAERLVSDYADAYVLQPGKMVFEIKPKGVDKGRALAA
EECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCEEEE
FLDEPPFAGRVPLFAGDDLTDEKGFAVVNARGGLSIKVGAGETSARMRLDSVDALHEQIA
ECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEECCCCCCHHEEHHHHHHHHHHHH
GWLGAGQPHA
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]