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The map label for this gene is era [H]

Identifier: 116689157

GI number: 116689157

Start: 1245919

End: 1246818

Strand: Direct

Name: era [H]

Synonym: Bcen2424_1135

Alternate gene names: 116689157

Gene position: 1245919-1246818 (Clockwise)

Preceding gene: 116689156

Following gene: 116689158

Centisome position: 35.76

GC content: 63.33

Gene sequence:

>900_bases
ATGAACACTCCCGCTCCTACCGGTTTCCGTTGCGGCATGATCGCGATCGTGGGCCGCCCGAACGTCGGCAAGTCGACGTT
GATGAACGCACTCGTCGGCCAGAAGATCAGCATCACGTCGCGCAAGGCGCAGACGACCCGCCACCGCATCACCGGCATCA
ACACGTTCGACGACGCGCAATTCGTGTTCGTCGACACGCCCGGTTTCCAGACCCGTCACAGCACCGCGCTGAACCGTTCG
CTGAACCGCGCGGTCACGTCGACGCTGACGTCGGTCGACGTGATCCTGTTCGTGATCGAGGCCGGCCGCTTCGGGCCCGA
CGACCAGAAGGTGCTCGACCTGATCCCGCCCGGCATGCCGACGCTGCTGATCGCGAACAAGATCGACCGCGTGAACGACA
AGGCCACGCTGTTCCCGTTCATGCAGAAGGTGAGCGAGCTGCGCGAATTCACCGAGCTCGTGCCGCTGTCGGCGCAGAAG
CCGGAAGACATCAAGCGCCTGCTGGACACGATCAAGCCGTACCTGCCGGAAGGCGAGCCGATCTACGGCGAGGACGAGCT
GACCGACCGCAGCTCGCGTTTTCTCGCGGCCGAAATCCTGCGCGAGAAGGTGTTTCGCTGGACTGGCGACGAGCTGCCGT
ACACGAGCACCGTGCTGATCGACAAGTTCGAGGAAGAGGGCCGCCTGAAGCGCATCTTCGCGACGATCCTCGTCGAGCGC
GATTCGCACAAGGCGATGGTGATCGGCAAGAAGGGCGAGAAGCTCAAGCAGATCAGCACCGAGGCGCGGATGGACATGGA
AAAGCTGTTCGACGGCCCCGTGTACCTCGAGACCTTCGTGAAGGTGAAGAGCGGCTGGGCCGACAACGAGGCGGGGCTGC
GTGCCTATGGGTACGAATGA

Upstream 100 bases:

>100_bases
TGCTGCCGCGCAGGCGCGCGTGGCCGATGCCGACCACTGAACTGCCCAGCGATCGTGCCGCGCGCCGCGCGGCCGTTTCC
GAACCTGTCTCCCAAACGAT

Downstream 100 bases:

>100_bases
CGCGCTGACGTCGACCGAAGACGCGGTGACGGCCGGCGCGAACGACGCGCCGCTGCCGGCACCGCCCGAACCGCCGCGCA
AGGCGCGGCGCGCGACGTCT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNTPAPTGFRCGMIAIVGRPNVGKSTLMNALVGQKISITSRKAQTTRHRITGINTFDDAQFVFVDTPGFQTRHSTALNRS
LNRAVTSTLTSVDVILFVIEAGRFGPDDQKVLDLIPPGMPTLLIANKIDRVNDKATLFPFMQKVSELREFTELVPLSAQK
PEDIKRLLDTIKPYLPEGEPIYGEDELTDRSSRFLAAEILREKVFRWTGDELPYTSTVLIDKFEEEGRLKRIFATILVER
DSHKAMVIGKKGEKLKQISTEARMDMEKLFDGPVYLETFVKVKSGWADNEAGLRAYGYE

Sequences:

>Translated_299_residues
MNTPAPTGFRCGMIAIVGRPNVGKSTLMNALVGQKISITSRKAQTTRHRITGINTFDDAQFVFVDTPGFQTRHSTALNRS
LNRAVTSTLTSVDVILFVIEAGRFGPDDQKVLDLIPPGMPTLLIANKIDRVNDKATLFPFMQKVSELREFTELVPLSAQK
PEDIKRLLDTIKPYLPEGEPIYGEDELTDRSSRFLAAEILREKVFRWTGDELPYTSTVLIDKFEEEGRLKRIFATILVER
DSHKAMVIGKKGEKLKQISTEARMDMEKLFDGPVYLETFVKVKSGWADNEAGLRAYGYE
>Mature_299_residues
MNTPAPTGFRCGMIAIVGRPNVGKSTLMNALVGQKISITSRKAQTTRHRITGINTFDDAQFVFVDTPGFQTRHSTALNRS
LNRAVTSTLTSVDVILFVIEAGRFGPDDQKVLDLIPPGMPTLLIANKIDRVNDKATLFPFMQKVSELREFTELVPLSAQK
PEDIKRLLDTIKPYLPEGEPIYGEDELTDRSSRFLAAEILREKVFRWTGDELPYTSTVLIDKFEEEGRLKRIFATILVER
DSHKAMVIGKKGEKLKQISTEARMDMEKLFDGPVYLETFVKVKSGWADNEAGLRAYGYE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=331, Percent_Identity=25.6797583081571, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788919, Length=291, Percent_Identity=50.5154639175258, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI87082120, Length=185, Percent_Identity=26.4864864864865, Blast_Score=61, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24646434, Length=305, Percent_Identity=24.9180327868852, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33633; Mature: 33633

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPAPTGFRCGMIAIVGRPNVGKSTLMNALVGQKISITSRKAQTTRHRITGINTFDDAQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCE
FVFVDTPGFQTRHSTALNRSLNRAVTSTLTSVDVILFVIEAGRFGPDDQKVLDLIPPGMP
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCC
TLLIANKIDRVNDKATLFPFMQKVSELREFTELVPLSAQKPEDIKRLLDTIKPYLPEGEP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
IYGEDELTDRSSRFLAAEILREKVFRWTGDELPYTSTVLIDKFEEEGRLKRIFATILVER
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECHHHCCHHHHHHHHHHHCC
DSHKAMVIGKKGEKLKQISTEARMDMEKLFDGPVYLETFVKVKSGWADNEAGLRAYGYE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCC
>Mature Secondary Structure
MNTPAPTGFRCGMIAIVGRPNVGKSTLMNALVGQKISITSRKAQTTRHRITGINTFDDAQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCE
FVFVDTPGFQTRHSTALNRSLNRAVTSTLTSVDVILFVIEAGRFGPDDQKVLDLIPPGMP
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCC
TLLIANKIDRVNDKATLFPFMQKVSELREFTELVPLSAQKPEDIKRLLDTIKPYLPEGEP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
IYGEDELTDRSSRFLAAEILREKVFRWTGDELPYTSTVLIDKFEEEGRLKRIFATILVER
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECHHHCCHHHHHHHHHHHCC
DSHKAMVIGKKGEKLKQISTEARMDMEKLFDGPVYLETFVKVKSGWADNEAGLRAYGYE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]