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The map label for this gene is degP [H]

Identifier: 116689152

GI number: 116689152

Start: 1239835

End: 1241331

Strand: Direct

Name: degP [H]

Synonym: Bcen2424_1130

Alternate gene names: 116689152

Gene position: 1239835-1241331 (Clockwise)

Preceding gene: 116689151

Following gene: 116689153

Centisome position: 35.59

GC content: 68.47

Gene sequence:

>1497_bases
ATGACGAAACTCACGCTGCGCAAAGTGCTCGCGGCGGCGGCGCTGTGTGCCTGCCTGCCGCTCGTCCCGCAAACCGCGGT
CGCTGTCACGCCTCCGGCTGCCAGCCTTCCCGATTTCGCCGACCTCGTCGAAAAGGTCGGCCCGGCCGTCGTGAACATCC
GGACCACCGCCAACGTGCCGACGAGCGGCCCGCGCGGGATGCTCCCGCCCGGCTTCGACAACGGCGACATGTCGGAATTC
TTCCGGCGCTTCTTCGGCATTCCGCTGCCGCAGGCGCCCGGCAACGGCGGCGGCAACGGCAGCAACCCGAAGAACGCGCC
GGCGCCGGACAACGGGCCCGACACCGAGCAGAATCGCGGCGTCGGCTCGGGCTTCATCGTGTCGGCCGACGGTTACGTGA
TGACCAATGCGCACGTCGTCGACGATGCCGACACCATCTACGTGACGCTGACCGACAAGCGTGAATTCAAGGCGAAGCTG
ATCGGCGTCGACGACCGCACGGACGTCGCGGTCGTCAAGATCCAGGCGTCGAACCTGCCGGTCGTTGCGATCGGCGATTC
GAACAAGGTGCGCGTCGGCGAGTGGGTCGTCGCGATCGGTTCGCCGTTCGGCCTCGACAACACGGTCACGGCCGGCATCG
TCAGCTCGAAGAGCCGCAATACGGGCGACTACCTGCCGTTCATCCAGACCGACGTCGCCGTGAACCCCGGCAACTCGGGC
GGCCCGCTGATCAACATGCAGGGCGAGGTGATCGGCATCAACTCGCAGATCTACAGCCGCACCGGCGGCTTCATGGGCAT
TTCGTTCGCGATTCCGATCGACGAGGCGATGCGCGTGGCCGACCAGCTGAAGGCGACGGGCAAGGTCACGCGCGGCCGGA
TCGCGGTGGCGATCGGCGAGGTGACGAAGGACGTGGCCGACTCGATCGGGCTGCCGAAGGCCGAAGGCGCGCTCGTCAGC
AGCGTCGAGCCGGGCGGCCCGGCCGACAAGGCCGGCATCCAGCCGGGCGACATTATCCTGAAGTTCAACGGCCGTCCGGT
CGACGCGGCGTCGGACCTGCCGCGCATGGTCGGCGACACGAAGCCCGGCACGAAGGCGACGGTCAACGTGTGGCGCAAGG
GTCAGGCACGCGATCTGCCGATCACGATCGCCGAGACGCCGGCCGAGTCGACGGCCAAGGCCGAGCAGCGCAAGAACGCG
CCGCAGAAGCCGCGCCAGACCAATTCCCTCGGCCTGACGGTCAGCGACCTGACGGCGGAGCAGTTGAAGACGCTGAAGCT
GAAGAACGGGGTGCAGATCGACGGCGTCGACGGCCCGGCCGCCCGTGCGGGCCTGCAGCGCGGCGACATCGTGCTGCGCG
TCGGCGACACCGACATCACGAGCGCGAAGCAGTTCGCCGACGTGACCGCGCAGCTCGATCCGCAGAAGGCGGTCGCGGTG
CTCGTGCGGCGTGGCGACAACACGCAGTTCGTGCCGGTGCGGCCGCGCCAGAAGTAA

Upstream 100 bases:

>100_bases
TACTGGATCACCGTGCTCGGCGAAGTGCCGCCGGCGACGTTGCAGCAGTTCGCGTCTGCCATAGAATACAAGGCTTCCAA
GTAACGCTACGGCTTCCGAC

Downstream 100 bases:

>100_bases
CGCGCCGATGTTCACCCTCTACGGCCGCGGCTGGTGCCACCTGTGCGACGACATGCGCGACGCACTGGCGCCGGTGGCGG
CCGAATTCGGCGTCGCGGTC

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MTKLTLRKVLAAAALCACLPLVPQTAVAVTPPAASLPDFADLVEKVGPAVVNIRTTANVPTSGPRGMLPPGFDNGDMSEF
FRRFFGIPLPQAPGNGGGNGSNPKNAPAPDNGPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKL
IGVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSG
GPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVS
SVEPGGPADKAGIQPGDIILKFNGRPVDAASDLPRMVGDTKPGTKATVNVWRKGQARDLPITIAETPAESTAKAEQRKNA
PQKPRQTNSLGLTVSDLTAEQLKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFADVTAQLDPQKAVAV
LVRRGDNTQFVPVRPRQK

Sequences:

>Translated_498_residues
MTKLTLRKVLAAAALCACLPLVPQTAVAVTPPAASLPDFADLVEKVGPAVVNIRTTANVPTSGPRGMLPPGFDNGDMSEF
FRRFFGIPLPQAPGNGGGNGSNPKNAPAPDNGPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKL
IGVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSG
GPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVS
SVEPGGPADKAGIQPGDIILKFNGRPVDAASDLPRMVGDTKPGTKATVNVWRKGQARDLPITIAETPAESTAKAEQRKNA
PQKPRQTNSLGLTVSDLTAEQLKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFADVTAQLDPQKAVAV
LVRRGDNTQFVPVRPRQK
>Mature_497_residues
TKLTLRKVLAAAALCACLPLVPQTAVAVTPPAASLPDFADLVEKVGPAVVNIRTTANVPTSGPRGMLPPGFDNGDMSEFF
RRFFGIPLPQAPGNGGGNGSNPKNAPAPDNGPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLI
GVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGG
PLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVSS
VEPGGPADKAGIQPGDIILKFNGRPVDAASDLPRMVGDTKPGTKATVNVWRKGQARDLPITIAETPAESTAKAEQRKNAP
QKPRQTNSLGLTVSDLTAEQLKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFADVTAQLDPQKAVAVL
VRRGDNTQFVPVRPRQK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=281, Percent_Identity=38.7900355871886, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI22129776, Length=262, Percent_Identity=38.9312977099237, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=36.8, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=39.8406374501992, Blast_Score=148, Evalue=1e-35,
Organism=Escherichia coli, GI1789629, Length=499, Percent_Identity=37.4749498997996, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI1786356, Length=486, Percent_Identity=33.9506172839506, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789630, Length=294, Percent_Identity=38.0952380952381, Blast_Score=184, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=38.9312977099237, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52014; Mature: 51883

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTLRKVLAAAALCACLPLVPQTAVAVTPPAASLPDFADLVEKVGPAVVNIRTTANVP
CCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
TSGPRGMLPPGFDNGDMSEFFRRFFGIPLPQAPGNGGGNGSNPKNAPAPDNGPDTEQNRG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
VGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASNLP
CCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCC
VVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSG
EEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCC
GPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGE
CCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEHH
VTKDVADSIGLPKAEGALVSSVEPGGPADKAGIQPGDIILKFNGRPVDAASDLPRMVGDT
HHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCC
KPGTKATVNVWRKGQARDLPITIAETPAESTAKAEQRKNAPQKPRQTNSLGLTVSDLTAE
CCCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHCCHH
QLKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFADVTAQLDPQKAVAV
HHHHHHHCCCCEEECCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHEEEE
LVRRGDNTQFVPVRPRQK
EEECCCCCEEEECCCCCC
>Mature Secondary Structure 
TKLTLRKVLAAAALCACLPLVPQTAVAVTPPAASLPDFADLVEKVGPAVVNIRTTANVP
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
TSGPRGMLPPGFDNGDMSEFFRRFFGIPLPQAPGNGGGNGSNPKNAPAPDNGPDTEQNRG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
VGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASNLP
CCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCC
VVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSG
EEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCC
GPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGE
CCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEHH
VTKDVADSIGLPKAEGALVSSVEPGGPADKAGIQPGDIILKFNGRPVDAASDLPRMVGDT
HHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCC
KPGTKATVNVWRKGQARDLPITIAETPAESTAKAEQRKNAPQKPRQTNSLGLTVSDLTAE
CCCCCEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHCCHH
QLKTLKLKNGVQIDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFADVTAQLDPQKAVAV
HHHHHHHCCCCEEECCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHEEEE
LVRRGDNTQFVPVRPRQK
EEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]