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The map label for this gene is aroA [H]

Identifier: 116689068

GI number: 116689068

Start: 1159222

End: 1160526

Strand: Direct

Name: aroA [H]

Synonym: Bcen2424_1045

Alternate gene names: 116689068

Gene position: 1159222-1160526 (Clockwise)

Preceding gene: 116689067

Following gene: 116689069

Centisome position: 33.27

GC content: 68.12

Gene sequence:

>1305_bases
ATGGACTACCTCGATCTCGGCCCGTACTCCAGCGCATCGGGCACCGTGCGCCTGCCCGGCTCGAAGAGCATTTCGAACCG
CGTGCTGCTGCTCGCGGCGCTCGCCGAAGGCGAAACGACGATCACCAACCTGCTCGACTCCGACGACACGCGTGTGATGC
TCGACGCACTCGGCAAGCTCGGCGTGAAGCTCGCGCGCGATGGCGACACCTGTGTCGTCACCGGCACGCGCGGCGCGTTC
ACCGCGAAGACGGCCGACCTGTTCCTCGGCAACGCGGGCACGGCCGTGCGGCCGCTGACCGCCGCACTCGCGGTGAACGG
CGGCGACTACCGCGTGCACGGCGTGCCGCGCATGCACGAACGGCCGATCGGCGATCTCGTCGATGGCCTGCGCCAGATCG
GCGCGCAGATCGACTACGAGCTGAGCGAAGGTTACCCGCCGCTGCGGATCAAGCCCGCGACGATTTCGGTCGATGCGCCG
ATCCGCGTGCGCGGTGACGTGTCGAGCCAGTTCCTCACCGCGCTCCTGATGACGCTGCCGCTCGTGAAGGCGAAGGATGG
CCAGGCCGTCGTCGAAGTCGACGGCGAGCTGATCTCGAAACCGTACGTCGACATCACGATCCGGCTGATGGCGCGCTTCG
GCGTGACCGTCGAGCGCGACGGCTGGCAGCGCTTCGTGGTGCCGGCCGGCGTCCGCTACCGCTCGCCGGGGCGAATCATG
GTCGAGGGCGACGCGTCGTCCGCGTCGTATTTCCTCGCGGCCGGCGCGCTCGGCGGCGGCCCGCTGCGGGTCGAAGGCGT
GGGGCGGGCGAGTATCCAGGGTGACGTCGGTTTCGCGAATGCGCTGATGCAGATGGGCGCGAACGTGACGATGGGCGACG
ACTGGATCGACGTACGCGGCATCGGCCACGATCACGGCAAGCTCGAGCCGATCGACATGGACTTCAACCTGATTCCCGAC
GCGGCGATGACCATCGCGGTCGCGGCGCTGTTCGCGAACGGCACGAGCACGCTGCGCAACATCGCGAGCTGGCGCGTGAA
GGAGACCGACCGCATCGCCGCGATGGCGACCGAGTTGCGCAAGGTCGGCGCGATTGTCGAGGAAGGCCCCGACTATCTCG
TCGTCACGCCGCCGGAAAAGCTCACGCCGAACGCGGCGATCGATACGTACGACGATCACCGGATGGCGATGTGCTTCTCG
CTCGTCAGCCTGGGCGGCGTGCCCGTGCGGATCAACGATCCGAAGTGCGTCGGCAAGACGTTCCCCGACTATTTCGACCG
CTTCGCCGCGCTCGCCAAGGCCTGA

Upstream 100 bases:

>100_bases
GAAGCCGTATTCACGCGCTCGCGCGCCGCACGCAAGGCATGGCAGGAACGCGGCGGCACGCCCGCTGCCGAACCGGTCAA
GAAATAACAGGACGATTCCC

Downstream 100 bases:

>100_bases
CCCGACTGTTCCGATGAAATCGACCCGACCCTTTCACCCGACTCCCGTCATCACGATCGACGGCCCGACCGCTTCCGGCA
AGGGCACCGTCGCGGCGCTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAF
TAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYELSEGYPPLRIKPATISVDAP
IRVRGDVSSQFLTALLMTLPLVKAKDGQAVVEVDGELISKPYVDITIRLMARFGVTVERDGWQRFVVPAGVRYRSPGRIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIDVRGIGHDHGKLEPIDMDFNLIPD
AAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGAIVEEGPDYLVVTPPEKLTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA

Sequences:

>Translated_434_residues
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAF
TAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYELSEGYPPLRIKPATISVDAP
IRVRGDVSSQFLTALLMTLPLVKAKDGQAVVEVDGELISKPYVDITIRLMARFGVTVERDGWQRFVVPAGVRYRSPGRIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIDVRGIGHDHGKLEPIDMDFNLIPD
AAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGAIVEEGPDYLVVTPPEKLTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA
>Mature_434_residues
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAF
TAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYELSEGYPPLRIKPATISVDAP
IRVRGDVSSQFLTALLMTLPLVKAKDGQAVVEVDGELISKPYVDITIRLMARFGVTVERDGWQRFVVPAGVRYRSPGRIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIDVRGIGHDHGKLEPIDMDFNLIPD
AAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGAIVEEGPDYLVVTPPEKLTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=437, Percent_Identity=58.1235697940503, Blast_Score=464, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6320332, Length=450, Percent_Identity=39.1111111111111, Blast_Score=246, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46250; Mature: 46250

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALGKL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEHHHHHHHC
GVKLARDGDTCVVTGTRGAFTAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHE
CEEEECCCCEEEEECCCCCEEEEEEEEEECCCCCCHHHEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAQIDYELSEGYPPLRIKPATISVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCCCEEHHCCCCCCEEECCEEEECCCEEEECCCHHHHHHHHHHHCC
LVKAKDGQAVVEVDGELISKPYVDITIRLMARFGVTVERDGWQRFVVPAGVRYRSPGRIM
CEECCCCCEEEEECCHHHCCCCCEEEEEEHHHHCCEEECCCCEEEEEECCCEECCCCEEE
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIDVRG
EECCCCCCEEEEEECCCCCCCEEEEECCCEEECCCCHHHHHHHHCCCCEEECCCEEEEEE
IGHDHGKLEPIDMDFNLIPDAAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELR
CCCCCCCCEEECCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
KVGAIVEEGPDYLVVTPPEKLTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKT
HHHHHHHCCCCEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCC
FPDYFDRFAALAKA
CHHHHHHHHHHHCC
>Mature Secondary Structure
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALGKL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEHHHHHHHC
GVKLARDGDTCVVTGTRGAFTAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHE
CEEEECCCCEEEEECCCCCEEEEEEEEEECCCCCCHHHEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAQIDYELSEGYPPLRIKPATISVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCCCEEHHCCCCCCEEECCEEEECCCEEEECCCHHHHHHHHHHHCC
LVKAKDGQAVVEVDGELISKPYVDITIRLMARFGVTVERDGWQRFVVPAGVRYRSPGRIM
CEECCCCCEEEEECCHHHCCCCCEEEEEEHHHHCCEEECCCCEEEEEECCCEECCCCEEE
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFANALMQMGANVTMGDDWIDVRG
EECCCCCCEEEEEECCCCCCCEEEEECCCEEECCCCHHHHHHHHCCCCEEECCCEEEEEE
IGHDHGKLEPIDMDFNLIPDAAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELR
CCCCCCCCEEECCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
KVGAIVEEGPDYLVVTPPEKLTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKT
HHHHHHHCCCCEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCC
FPDYFDRFAALAKA
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA