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The map label for this gene is fbp [H]

Identifier: 116689037

GI number: 116689037

Start: 1119711

End: 1120724

Strand: Reverse

Name: fbp [H]

Synonym: Bcen2424_1014

Alternate gene names: 116689037

Gene position: 1120724-1119711 (Counterclockwise)

Preceding gene: 116689038

Following gene: 116689036

Centisome position: 32.17

GC content: 64.5

Gene sequence:

>1014_bases
ATGTCCATTGCCCGCCGCACCACGCTGTCGAAGTTCCTGATCGAACAGCAACGTGAGACCAACAACCTCCCCGCCGACCT
GCGCCTGCTGATCGAAGTCGTCGCCCGCGCGTGCAAGGCGATCAGCTACAACGTGTCGAAGGGCGCGCTCGGCGACGCGC
TCGGCACCGCCGGCAGCGAGAACGTCCAGGGCGAAGTGCAGAAGAAGCTCGACATCCTGTCGAACGAGATCCTGCTCGAC
GCGAACGAATGGGGCGGCAACCTCGCCGCGATGGCATCGGAAGAAATGGAAACGTTCTTCCCGATCCCGGCGAACTACCC
GCGCGGCGAATACCTGCTCGTGTTCGATCCGCTCGACGGCTCGTCGAACATCGACGTGAACGTGTCGATCGGCACGATCT
TCTCGGTGCTGCGCTGCCCGGACGGCAAGCAGGCGACCGAGGAGTCGTTCCTGCAGCCCGGCACCGAGCAGGTCGCGGCC
GGCTACGCCGTGTACGGCCCGCAGACGGTGTTCGTGCTGACGACCGGCAACGGCGTGAACTGCTTCACGCTCGACCGCGA
AGTCGGCTCGTGGGTGCTCACGCAGAGCAACATGCAGATCCCGGCCGACACGCGCGAATACGCGATCAACGCATCGAACG
CACGCCACTGGTACGACCCGGTCAAGCGCTACGTCGACGAGCTGAACGCCGGCAAGGACGGCCCGCGCGGCGACAACTTC
AACATGCGCTGGATCGCGTCGATGGTGGCCGACGTGCACCGGATCCTGAATCGCGGCGGCATCTTCATGTACCCGGCCGA
CAAGCGCACGCCCGATCGTCCGGGCAAGCTGCGTCTGATGTATGAAGCAAACCCGATGTCGTTCATCGTCGAACAGGCGG
GCGGCGCAGCGACGACCGGCACGCAGCGCATCATGGAAGTGCAGCCCACCGGCCTGCACCAGCGCGTGCCCGTGTTCCTC
GGTTCGAAGAACGAAGTCAAGCGCGTGACCGGCTATCACGACGAAGCAAAATAA

Upstream 100 bases:

>100_bases
GGCCCGGCCATGTAACCGGACGAAAAAAGCCGGCGGCACCGAAGGCGCGACGGGTAAAATTGCGGCCATTCAAGGATTCT
TTGGCCTTTCGGAGTCTGTC

Downstream 100 bases:

>100_bases
TTGCACTGCAGCACTGGACGAGGGTGCGAGACATCAGTACAATCGCGCCTTCGCGATGTGGCCCTAACGGGTCGCGTCGC
AGTGAAGTGAAAGCGGAAAG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTEQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFL
GSKNEVKRVTGYHDEAK

Sequences:

>Translated_337_residues
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTEQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFL
GSKNEVKRVTGYHDEAK
>Mature_336_residues
SIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLDA
NEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTEQVAAG
YAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNFN
MRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFLG
SKNEVKRVTGYHDEAK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=321, Percent_Identity=42.3676012461059, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI189083692, Length=319, Percent_Identity=42.3197492163009, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI16579888, Length=319, Percent_Identity=42.3197492163009, Blast_Score=249, Evalue=2e-66,
Organism=Escherichia coli, GI1790679, Length=324, Percent_Identity=44.7530864197531, Blast_Score=274, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI17508131, Length=325, Percent_Identity=43.0769230769231, Blast_Score=271, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6323409, Length=326, Percent_Identity=39.8773006134969, Blast_Score=256, Evalue=5e-69,
Organism=Drosophila melanogaster, GI45550998, Length=325, Percent_Identity=44, Blast_Score=262, Evalue=2e-70,
Organism=Drosophila melanogaster, GI19921562, Length=325, Percent_Identity=44, Blast_Score=262, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37126; Mature: 36995

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSE
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEE
CFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
EEEECCCCCCEEEECCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCEEHEECCCCCCCCC
TQRIMEVQPTGLHQRVPVFLGSKNEVKRVTGYHDEAK
CHHEEEECCCCCCCCCCEEECCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
SIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSE
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEE
CFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
EEEECCCCCCEEEECCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCCEEHEECCCCCCCCC
TQRIMEVQPTGLHQRVPVFLGSKNEVKRVTGYHDEAK
CHHEEEECCCCCCCCCCEEECCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA