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The map label for this gene is yfdZ [C]

Identifier: 116688977

GI number: 116688977

Start: 1061011

End: 1062207

Strand: Reverse

Name: yfdZ [C]

Synonym: Bcen2424_0954

Alternate gene names: 116688977

Gene position: 1062207-1061011 (Counterclockwise)

Preceding gene: 116688978

Following gene: 116688975

Centisome position: 30.49

GC content: 68.76

Gene sequence:

>1197_bases
ATGAATACCACCGCCGATTCGCTCGTCACGCTCGCCGCACGCGTCGACGCGATCCAGCCCTTTCATGTGATGGAACTGAT
GAAGGAGGCACAGCGGCTCGAGTCCTTGGGGCGCGATGTTATCCACATGGGCATCGGCGAGCCGGATTTCACCGCGCCGG
AGCCGGTTGTCGAGGCCGCCGCGGCCGCGCTGCGCCGCGGCGTCACGCAGTACACGAGCGCGCTCGGCATCGCGCCGCTG
CGCGAGGCGATCGCCGCGCACTATGCACGCGCATACGGCCTCACGGTCGCCCCCGATCGGATCGTGGTGACGGCCGGCGC
ATCGGCCGCGCTGCTGCTCGCATGCCTCGCGCTGGTCGGCCGCGACGACGAAGTGCTGATGCCCGATCCGTCCTACCCGT
GCAACCGGCACTTCGTCGCGGCGGCCGAAGGCCGTCCGGTGCTCGTGCCGAGCGGCCCGGACGCGCGCTTCCAGCTCACC
GAAAACGACGTCCGCACGTACTGGAACGAGCGCACGCGCGGCGTGCTGCTCGCGTCGCCATCGAATCCGACCGGCACGTC
GCTCGAACCGGACGAACTGAAGCGGATCGTCGAAGCGGTGCGCGCACGCGGCGGCTTCACGATCGTCGACGAGATCTACC
AGGGGCTCAGCTACGACGCCGCGCCGGTGTCGGCGCTGTCGTTCGGCGACGACGTGATCACCGTGAACAGCTTCTCGAAG
TATTTCAGCATGACGGGCTGGCGGCTCGGCTGGCTCGTCGTGCCGCCCGCGCTCGTCGGCACGTTCGAAAAGCTCTCGCA
GAACCTGTTCATCTGCCCGTCCGCACTCGCGCAACATGCGGCGCTCGCCTGCTTCGAACCCGCGACGCTCGACATCTACG
AAACACGCCGGCTCGAATTCAAGCGCCGCCGCGATTTCATCGCGCCGGCGCTGGAGCGGCTCGGCTTCACGGTGCCGGTG
ATGCCGGACGGCGCGTTCTACGTCTATGCGCATTGCGGCGGCGTCGCGCACCCGGCGGCGGGCGACAGCGCTACGCTCAC
GCAGGCGATGCTGCACGACGCTGGCGTGGTGCTGGTGCCGGGCATGGACTTCGGTGTCCATGCGCCGCGGGACTATATCC
GCCTGTCCTATGCGACCGCCTACTCGCGGCTCGAAGAGGCGGTCGACCGGCTCGGGACGCTGTTCGGGCAGCACTGA

Upstream 100 bases:

>100_bases
GCCGAAACGCAGGCGCGTCGCAACGGCTGACGCCGCTGGTTGGTCCACGGGCGCGCAAGCGCCCGTTTTTCATTCTTTTC
TCCCTCCGCCCTGCCCGCCG

Downstream 100 bases:

>100_bases
CACCGCGCCCGGCGCACCGGGCGCTTCACACACCGCAAAAAAGAAAAGGCACCCGAATCGGGTGCCTTTCTCATGCCCAG
TCGTGCCGGCCGAAGCCGCA

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNTTADSLVTLAARVDAIQPFHVMELMKEAQRLESLGRDVIHMGIGEPDFTAPEPVVEAAAAALRRGVTQYTSALGIAPL
REAIAAHYARAYGLTVAPDRIVVTAGASAALLLACLALVGRDDEVLMPDPSYPCNRHFVAAAEGRPVLVPSGPDARFQLT
ENDVRTYWNERTRGVLLASPSNPTGTSLEPDELKRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALSFGDDVITVNSFSK
YFSMTGWRLGWLVVPPALVGTFEKLSQNLFICPSALAQHAALACFEPATLDIYETRRLEFKRRRDFIAPALERLGFTVPV
MPDGAFYVYAHCGGVAHPAAGDSATLTQAMLHDAGVVLVPGMDFGVHAPRDYIRLSYATAYSRLEEAVDRLGTLFGQH

Sequences:

>Translated_398_residues
MNTTADSLVTLAARVDAIQPFHVMELMKEAQRLESLGRDVIHMGIGEPDFTAPEPVVEAAAAALRRGVTQYTSALGIAPL
REAIAAHYARAYGLTVAPDRIVVTAGASAALLLACLALVGRDDEVLMPDPSYPCNRHFVAAAEGRPVLVPSGPDARFQLT
ENDVRTYWNERTRGVLLASPSNPTGTSLEPDELKRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALSFGDDVITVNSFSK
YFSMTGWRLGWLVVPPALVGTFEKLSQNLFICPSALAQHAALACFEPATLDIYETRRLEFKRRRDFIAPALERLGFTVPV
MPDGAFYVYAHCGGVAHPAAGDSATLTQAMLHDAGVVLVPGMDFGVHAPRDYIRLSYATAYSRLEEAVDRLGTLFGQH
>Mature_398_residues
MNTTADSLVTLAARVDAIQPFHVMELMKEAQRLESLGRDVIHMGIGEPDFTAPEPVVEAAAAALRRGVTQYTSALGIAPL
REAIAAHYARAYGLTVAPDRIVVTAGASAALLLACLALVGRDDEVLMPDPSYPCNRHFVAAAEGRPVLVPSGPDARFQLT
ENDVRTYWNERTRGVLLASPSNPTGTSLEPDELKRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALSFGDDVITVNSFSK
YFSMTGWRLGWLVVPPALVGTFEKLSQNLFICPSALAQHAALACFEPATLDIYETRRLEFKRRRDFIAPALERLGFTVPV
MPDGAFYVYAHCGGVAHPAAGDSATLTQAMLHDAGVVLVPGMDFGVHAPRDYIRLSYATAYSRLEEAVDRLGTLFGQH

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=417, Percent_Identity=27.0983213429257, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI169881279, Length=417, Percent_Identity=27.0983213429257, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI56713254, Length=316, Percent_Identity=27.8481012658228, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI56713256, Length=316, Percent_Identity=27.8481012658228, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI4507369, Length=381, Percent_Identity=24.1469816272966, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI169881281, Length=415, Percent_Identity=22.6506024096386, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=28.7878787878788, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=29.9450549450549, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788627, Length=364, Percent_Identity=28.021978021978, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787710, Length=341, Percent_Identity=26.6862170087977, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=28.3163265306122, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=27.8061224489796, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17567369, Length=325, Percent_Identity=27.6923076923077, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=385, Percent_Identity=26.4935064935065, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=23.5294117647059, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573069, Length=384, Percent_Identity=28.3854166666667, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646114, Length=384, Percent_Identity=28.3854166666667, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573067, Length=384, Percent_Identity=28.3854166666667, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573065, Length=384, Percent_Identity=28.3854166666667, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=24.6073298429319, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43063; Mature: 43063

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTADSLVTLAARVDAIQPFHVMELMKEAQRLESLGRDVIHMGIGEPDFTAPEPVVEAA
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCHHHHHHH
AAALRRGVTQYTSALGIAPLREAIAAHYARAYGLTVAPDRIVVTAGASAALLLACLALVG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCHHHHHHHHHHHHC
RDDEVLMPDPSYPCNRHFVAAAEGRPVLVPSGPDARFQLTENDVRTYWNERTRGVLLASP
CCCCEECCCCCCCCCCCEEEECCCCEEEEECCCCCEEEECHHHHHHHHHHCCCEEEEECC
SNPTGTSLEPDELKRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALSFGDDVITVNSFSK
CCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCHHEECCCCEEEECCHHH
YFSMTGWRLGWLVVPPALVGTFEKLSQNLFICPSALAQHAALACFEPATLDIYETRRLEF
HHHCCCCEEEEEECCHHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCEEEHHHHHHHHH
KRRRDFIAPALERLGFTVPVMPDGAFYVYAHCGGVAHPAAGDSATLTQAMLHDAGVVLVP
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEC
GMDFGVHAPRDYIRLSYATAYSRLEEAVDRLGTLFGQH
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTTADSLVTLAARVDAIQPFHVMELMKEAQRLESLGRDVIHMGIGEPDFTAPEPVVEAA
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCHHHHHHH
AAALRRGVTQYTSALGIAPLREAIAAHYARAYGLTVAPDRIVVTAGASAALLLACLALVG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCHHHHHHHHHHHHC
RDDEVLMPDPSYPCNRHFVAAAEGRPVLVPSGPDARFQLTENDVRTYWNERTRGVLLASP
CCCCEECCCCCCCCCCCEEEECCCCEEEEECCCCCEEEECHHHHHHHHHHCCCEEEEECC
SNPTGTSLEPDELKRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALSFGDDVITVNSFSK
CCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCHHEECCCCEEEECCHHH
YFSMTGWRLGWLVVPPALVGTFEKLSQNLFICPSALAQHAALACFEPATLDIYETRRLEF
HHHCCCCEEEEEECCHHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCEEEHHHHHHHHH
KRRRDFIAPALERLGFTVPVMPDGAFYVYAHCGGVAHPAAGDSATLTQAMLHDAGVVLVP
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEC
GMDFGVHAPRDYIRLSYATAYSRLEEAVDRLGTLFGQH
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]