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The map label for this gene is capD [H]

Identifier: 116688910

GI number: 116688910

Start: 995137

End: 997020

Strand: Direct

Name: capD [H]

Synonym: Bcen2424_0887

Alternate gene names: 116688910

Gene position: 995137-997020 (Clockwise)

Preceding gene: 116688909

Following gene: 116688916

Centisome position: 28.56

GC content: 64.86

Gene sequence:

>1884_bases
ATGTTGCGATCCAGAGCATCTTGGCTGTCCCTGAGTGCTTTCCTGTTCGACCTGACGGCGGTTGTCGCCGCATGGTTGTT
CGCTTATCTCGTTCGTTTCAACGGCAGCGTTCCGCATGATTTCCTGAGCGGCGCGCTGATGGCGCTGACGTGGGCACTGC
CCGTCTATGCGCTGATGTTCCGCGGCTTCGGCCTGTATCGCGGGCTGTGGGTGTTCGCCAGCCTGCCCGATCTGATGCGC
ATCGCGAAGGCGGTGGCCGGCGGCGGCGTGATCGTGATGATCGGTGCCGTGATGTTCCAGCCGCAGCCGATCATTCCGCG
CTCGGTGCTGCTGGTGTCGCCGTTGATGCTGTTCCTGGCAATGGGTGGCGCGCGTGCGCTGTATCGCGCGACGAAGGAGT
ACTACCTGTACGGTGGGCTGGTAGGCAAGGGCAAGCCGGTGCTGGTGCTGGGTGCCGGCACGGCCGGCGCGAGCCTCGCG
CGCGAACTGTCGCGCTCCGGTGAATGGCGCTTGGTCGGCCTGCTCGACGACGACGTCACGAAACAGGGGCGCGAAATCTA
CGGCTACAAGGTGCTGGGCTCGTTCAACGACCTCAAGCACTGGACCGATGCGATGAAGGTCGAATACGCGATCATCGCGA
TTCCGTCGGCGTCGGTCGAAACACAGCGTCGCGTCGCGACCCTGTGCGTGCGGGCCGGCGTGAAGGCGATGGTGCTGCCG
TCGCTGACCGCGCTGATGCCGGGGCAGGGCTTCCTGTCGCAGGTACGGAACATCGATCTCGAGGATCTGCTCGGCCGCGA
CGCGGTGACGATCGATACGCCGCACGTCGAGGCGCTGCTGCGCGGCCGCGTCGTGATGGTGACCGGCGCGGGCGGCTCGA
TCGGCTCCGAGCTGTGCCGGCAGATCCTGCGCTTCGCCCCTGCGCAGCTCGTTGCATTCGATCTCTCCGAATACGCGATG
TACCGGCTGACCGAGGAATTGCGTGAGCGTTTTCCGGATCTGCCCGTGGTGCCGATCATCGGCGATGCGAAGGATTCGCT
GCTGCTCGACCAGGTGATGTCGCGTCACGCGCCGCACATCGTGTTCCATGCGGCCGCCTACAAGCACGTGCCGTTGATGG
AAGAGCACAACGCATGGCAGGCGCTGCGCAACAACGTGCTCGGCACCTATCGCGTGGCGCGGGCGGCGATCCGCCACGAC
GTGCGTCACTTCGTGTTGATCTCGACCGACAAGGCGGTCAATCCGACCAACGTGATGGGCGCGAGCAAGCGTCTCGCGGA
AATGGCCTGCCAGGCGTTGCAGCAGTCGAGCGGGCGTACGCAGTTCGAGACGGTGCGCTTCGGCAACGTGCTCGGCAGCG
CGGGCAGCGTGATTCCGAAGTTTCAGCAGCAGATCGCGAAGGGCGGTCCGGTGACGGTCACGCACCCGGAGATCACGCGT
TTCTTCATGACGATCCCGGAAGCGTCGCAGCTCGTGCTGCAGGCGTCGAGCATGGGGCATGGCGGCGAGATCTTCATTCT
CGATATGGGCGAGCCGGTGAAGATCGTCGATCTCGCGTGCGACCTGATCCGCCTGTACGGTTTCTCGGAAGAACAGATTC
GCATCGAGTTCACCGGGCTGCGGCCGGGCGAGAAGCTCTACGAGGAGTTGCTCGCGGATGACGAGGCGACGACGCGCACG
CCGCACCCGAAGCTGCGGATCGCACGTGCGCGCGAAGTGCCGGACAATTTCCTCGACGAATTGCTGCCGTGGCTGATGCA
GCATCGCGTGCTGTCCGACGACGAGGTACGGCGCGATCTGCGGCGCTGGGTGCCGGAATACCAGACGGCCGTTGCCCCTA
TGTTGCAGAGCGTGCCGTCGGTGCGCGTCGTATCGAACGGGTGA

Upstream 100 bases:

>100_bases
TGCTTGGTATGGCGTCCTGGCATGGTTCGGATGGTTGATCGACCTGCGTTGGCGCCGGTTTCAAGCGGCCGCCGAAAACA
ATTCTTGAGGTTTCCCGCCG

Downstream 100 bases:

>100_bases
TGCGGTCCCCCGGCCGTGAACTGAACGGCAAGAAGAGAAAAAGCGCCCGGCAGGGCGCTTTTTTTCGTCCAGAAACGGTT
ACGCGATTCAGCGGCCGGGC

Product: polysaccharide biosynthesis protein CapD

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MLRSRASWLSLSAFLFDLTAVVAAWLFAYLVRFNGSVPHDFLSGALMALTWALPVYALMFRGFGLYRGLWVFASLPDLMR
IAKAVAGGGVIVMIGAVMFQPQPIIPRSVLLVSPLMLFLAMGGARALYRATKEYYLYGGLVGKGKPVLVLGAGTAGASLA
RELSRSGEWRLVGLLDDDVTKQGREIYGYKVLGSFNDLKHWTDAMKVEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCRQILRFAPAQLVAFDLSEYAM
YRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRHAPHIVFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVARAAIRHD
VRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQSSGRTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPVKIVDLACDLIRLYGFSEEQIRIEFTGLRPGEKLYEELLADDEATTRT
PHPKLRIARAREVPDNFLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQTAVAPMLQSVPSVRVVSNG

Sequences:

>Translated_627_residues
MLRSRASWLSLSAFLFDLTAVVAAWLFAYLVRFNGSVPHDFLSGALMALTWALPVYALMFRGFGLYRGLWVFASLPDLMR
IAKAVAGGGVIVMIGAVMFQPQPIIPRSVLLVSPLMLFLAMGGARALYRATKEYYLYGGLVGKGKPVLVLGAGTAGASLA
RELSRSGEWRLVGLLDDDVTKQGREIYGYKVLGSFNDLKHWTDAMKVEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCRQILRFAPAQLVAFDLSEYAM
YRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRHAPHIVFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVARAAIRHD
VRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQSSGRTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPVKIVDLACDLIRLYGFSEEQIRIEFTGLRPGEKLYEELLADDEATTRT
PHPKLRIARAREVPDNFLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQTAVAPMLQSVPSVRVVSNG
>Mature_627_residues
MLRSRASWLSLSAFLFDLTAVVAAWLFAYLVRFNGSVPHDFLSGALMALTWALPVYALMFRGFGLYRGLWVFASLPDLMR
IAKAVAGGGVIVMIGAVMFQPQPIIPRSVLLVSPLMLFLAMGGARALYRATKEYYLYGGLVGKGKPVLVLGAGTAGASLA
RELSRSGEWRLVGLLDDDVTKQGREIYGYKVLGSFNDLKHWTDAMKVEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCRQILRFAPAQLVAFDLSEYAM
YRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRHAPHIVFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVARAAIRHD
VRHFVLISTDKAVNPTNVMGASKRLAEMACQALQQSSGRTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPVKIVDLACDLIRLYGFSEEQIRIEFTGLRPGEKLYEELLADDEATTRT
PHPKLRIARAREVPDNFLDELLPWLMQHRVLSDDEVRRDLRRWVPEYQTAVAPMLQSVPSVRVVSNG

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 69264; Mature: 69264

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSRASWLSLSAFLFDLTAVVAAWLFAYLVRFNGSVPHDFLSGALMALTWALPVYALMF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RGFGLYRGLWVFASLPDLMRIAKAVAGGGVIVMIGAVMFQPQPIIPRSVLLVSPLMLFLA
HCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHH
MGGARALYRATKEYYLYGGLVGKGKPVLVLGAGTAGASLARELSRSGEWRLVGLLDDDVT
CCCHHHHHHHHHHHEEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHH
KQGREIYGYKVLGSFNDLKHWTDAMKVEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
HCCCCEEEEEEECCCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCR
HHHHHCCCHHHHHHHHCCCHHHHCCCCCEEECCHHHHHHHCCCEEEEECCCCCHHHHHHH
QILRFAPAQLVAFDLSEYAMYRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRHAPHI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEE
VFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVARAAIRHDVRHFVLISTDKAVNPTNVMG
EEEHHHHHCCCCHHHCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
ASKRLAEMACQALQQSSGRTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECHHHHH
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPVKIVDLACDLIRLYGFSEEQIRIEFTGL
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
RPGEKLYEELLADDEATTRTPHPKLRIARAREVPDNFLDELLPWLMQHRVLSDDEVRRDL
CCHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
RRWVPEYQTAVAPMLQSVPSVRVVSNG
HHHHHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MLRSRASWLSLSAFLFDLTAVVAAWLFAYLVRFNGSVPHDFLSGALMALTWALPVYALMF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RGFGLYRGLWVFASLPDLMRIAKAVAGGGVIVMIGAVMFQPQPIIPRSVLLVSPLMLFLA
HCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHH
MGGARALYRATKEYYLYGGLVGKGKPVLVLGAGTAGASLARELSRSGEWRLVGLLDDDVT
CCCHHHHHHHHHHHEEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHH
KQGREIYGYKVLGSFNDLKHWTDAMKVEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
HCCCCEEEEEEECCCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCR
HHHHHCCCHHHHHHHHCCCHHHHCCCCCEEECCHHHHHHHCCCEEEEECCCCCHHHHHHH
QILRFAPAQLVAFDLSEYAMYRLTEELRERFPDLPVVPIIGDAKDSLLLDQVMSRHAPHI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEE
VFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVARAAIRHDVRHFVLISTDKAVNPTNVMG
EEEHHHHHCCCCHHHCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHH
ASKRLAEMACQALQQSSGRTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECHHHHH
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPVKIVDLACDLIRLYGFSEEQIRIEFTGL
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
RPGEKLYEELLADDEATTRTPHPKLRIARAREVPDNFLDELLPWLMQHRVLSDDEVRRDL
CCHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
RRWVPEYQTAVAPMLQSVPSVRVVSNG
HHHHHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]