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The map label for this gene is pgm [H]

Identifier: 116688916

GI number: 116688916

Start: 1002717

End: 1004186

Strand: Direct

Name: pgm [H]

Synonym: Bcen2424_0893

Alternate gene names: 116688916

Gene position: 1002717-1004186 (Clockwise)

Preceding gene: 116688910

Following gene: 116688917

Centisome position: 28.78

GC content: 66.6

Gene sequence:

>1470_bases
ATGCGCGGCACCCGTGAGCGGCGGCCCGCGCAAGCCAGACAATTTTCCATGCACGCAACTGAGAGAAGAGAATCGATGAT
CTCCCAATCCATCTTCAAGGCATATGACATTCGTGGCGTGGTCGGCAAGACACTCGACGTCGACACGGCGCGCGGAATCG
GCCGGGCATTCGGCAGCGAAGTCCGTGCGCAGGGCGGCGATGCGGTCGTCGTCGCGCGCGACGGCCGCCTGTCCGGGCCG
GAACTGGTCGGCGCGCTGGCCGACGGCCTGCGTGCGGCCGGGGTCGACGTCGTCGACGTCGGCATGGTGCCGACGCCGGT
CGGTTATTTCGCGGCGAACGTGCCGCTGGCGCTGAAGGGCGGCGAGCGCCGCGTCGATTCGTGCATCGTCGTCACGGGCA
GTCACAATCCGCCCGACTACAACGGCTTCAAGATGGTGCTGCGCGGCGCCGCGATCTACGGCGAGCAGATCCAGGCGCTG
TACCGCCGCATCGTCGACGAGCGGTTCGAGTCCGGCAGCGGCACCTATGAGCAGATCGACGTCGCGGATCAATACATCGC
GCGCATCGTCGGCGACGTGAAGCTCGCGCGGCCGCTGAAGATCGTGGTCGACGCCGGCAACGGCGTCGCAGGCCCCCTCG
CGACGCGCCTGTTCAAGGCGCTCGGCTGCGAACTCGTCGAGCGCTTCACCGACATCGACGGCACGTTCCCGAACCATCAC
CCCGATCCCGCCCACCCGGAAAACCTGCAGGACGTGATCCAGGCGCTGAAGGACACCGATGCGGAACTCGGCTTCGCGTT
CGACGGCGACGGCGACCGCCTGGGCGTCGTCACGAAGGACGGCCAGATCATCTATCCGGACCGCCAGCTGATGCTGTTCG
CGGAAGAAGTGCTGTCGCGCAACCCGGGCGCGCAGATCATCTACGACGTGAAGTGCACGCGCCACCTCGCGCAGTGGGTG
AAGTCGAAGGGCGGCGAGCCGCTGATGTGGAAGACGGGTCACTCGCTCGTGAAGGCGAAGCTGCGCGAGACGGGTGCGCC
GCTCGCCGGCGAAATGAGCGGCCACGTGTTCTTCAAGGATCGCTGGTACGGCTTCGACGACGGCCTGTACACCGGTGCGC
GCCTGCTCGAGATTCTCGCGAAGACGGCCGATCCGAGCGCGCTGCTCAACAGCCTGCCGGACGCGATGAGCACGCCGGAA
CTGCAGCTCTGGCTCGACGAAGGCGAGAATTTCCGCCTGATCGAGCAGTTGCAGAAAGAGGCGAAGTTCGACGGCGCCGA
TGAAGTCGTGACGATCGACGGCCTGCGTGTCGAGTACCCGGACGGCTTCGGCCTCGCGCGTTCGTCGAACACGACGCCGG
TCGTCGTGATGCGCTTCGAGGCCGAGACGCAGGAAGGGCTCAAGCGCATCCAGGAAGACTTCCGCCGCGTGCTGACGGCC
GCGAAGCCGGACGTCAAGCTGCCGTTCTGA

Upstream 100 bases:

>100_bases
TTAAAATGGGCGACATGCGCGTCATCAAAACCCGCGATTATAAGTGGGATCGCGGCTGCTCCAGCCGTTGTGCGCGGTGT
TCCGCCGGCAGGCATGTATC

Downstream 100 bases:

>100_bases
GCGCCGGCGGCCGGCGGGCCGCCCGTACGACGGCCGGTTCGTCGGCCGTGTTTGTCTCGAAAAGCGGCGCGTGCCCCGGG
CGCGCGGCCGCTTTTTGTCT

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MRGTRERRPAQARQFSMHATERRESMISQSIFKAYDIRGVVGKTLDVDTARGIGRAFGSEVRAQGGDAVVVARDGRLSGP
ELVGALADGLRAAGVDVVDVGMVPTPVGYFAANVPLALKGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQAL
YRRIVDERFESGSGTYEQIDVADQYIARIVGDVKLARPLKIVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHH
PDPAHPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWV
KSKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILAKTADPSALLNSLPDAMSTPE
LQLWLDEGENFRLIEQLQKEAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEAETQEGLKRIQEDFRRVLTA
AKPDVKLPF

Sequences:

>Translated_489_residues
MRGTRERRPAQARQFSMHATERRESMISQSIFKAYDIRGVVGKTLDVDTARGIGRAFGSEVRAQGGDAVVVARDGRLSGP
ELVGALADGLRAAGVDVVDVGMVPTPVGYFAANVPLALKGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQAL
YRRIVDERFESGSGTYEQIDVADQYIARIVGDVKLARPLKIVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHH
PDPAHPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWV
KSKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILAKTADPSALLNSLPDAMSTPE
LQLWLDEGENFRLIEQLQKEAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEAETQEGLKRIQEDFRRVLTA
AKPDVKLPF
>Mature_489_residues
MRGTRERRPAQARQFSMHATERRESMISQSIFKAYDIRGVVGKTLDVDTARGIGRAFGSEVRAQGGDAVVVARDGRLSGP
ELVGALADGLRAAGVDVVDVGMVPTPVGYFAANVPLALKGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQAL
YRRIVDERFESGSGTYEQIDVADQYIARIVGDVKLARPLKIVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHH
PDPAHPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWV
KSKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILAKTADPSALLNSLPDAMSTPE
LQLWLDEGENFRLIEQLQKEAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEAETQEGLKRIQEDFRRVLTA
AKPDVKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=471, Percent_Identity=36.3057324840764, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1789566, Length=480, Percent_Identity=27.2916666666667, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 53588; Mature: 53588

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGTRERRPAQARQFSMHATERRESMISQSIFKAYDIRGVVGKTLDVDTARGIGRAFGSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHH
VRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDVGMVPTPVGYFAANVPLALKG
HHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCEEECC
GERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYRRIVDERFESGSGTYEQID
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VADQYIARIVGDVKLARPLKIVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHH
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PDPAHPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSR
CCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCC
NPGAQIIYDVKCTRHLAQWVKSKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKD
CCCCCEEEEHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEC
RWYGFDDGLYTGARLLEILAKTADPSALLNSLPDAMSTPELQLWLDEGENFRLIEQLQKE
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCCEEEEECCCCCCHHHHHHHHH
AKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEAETQEGLKRIQEDFRRVLTA
HCCCCCCCEEEECCEEEECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
AKPDVKLPF
CCCCCCCCC
>Mature Secondary Structure
MRGTRERRPAQARQFSMHATERRESMISQSIFKAYDIRGVVGKTLDVDTARGIGRAFGSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHH
VRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDVGMVPTPVGYFAANVPLALKG
HHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCEEECC
GERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYRRIVDERFESGSGTYEQID
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VADQYIARIVGDVKLARPLKIVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHH
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PDPAHPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSR
CCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCC
NPGAQIIYDVKCTRHLAQWVKSKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKD
CCCCCEEEEHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEC
RWYGFDDGLYTGARLLEILAKTADPSALLNSLPDAMSTPELQLWLDEGENFRLIEQLQKE
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCCEEEEECCCCCCHHHHHHHHH
AKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEAETQEGLKRIQEDFRRVLTA
HCCCCCCCEEEECCEEEECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
AKPDVKLPF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]