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The map label for this gene is hcrC [H]

Identifier: 116688855

GI number: 116688855

Start: 933608

End: 935194

Strand: Direct

Name: hcrC [H]

Synonym: Bcen2424_0832

Alternate gene names: 116688855

Gene position: 933608-935194 (Clockwise)

Preceding gene: 116688853

Following gene: 116688856

Centisome position: 26.8

GC content: 69.25

Gene sequence:

>1587_bases
ATGAGTGAGCCGATCCGCTTCTACCATCGTCACGCGATCCGCGAAGTCAGCGGCGCGGACGTGACCCGCACCGTGCTGCA
ATACCTGCGCGAGGACGCGCATTGCACCGGCACCAAGGAAGGCTGCGCGGAAGGCGACTGCGGCGCGTGCACGGTCGTCG
TCGGCGAGCTGACCGATGCCGGCGCGGTCGAGTTCAAGGCCGTCAACGCATGCATCCAGTTCCTGCCGACGCTCGACGGC
AAGGCGCTCCTGACGGTCGAGGACCTGCGCCAGCCGGACGGCACGCTGCATCCGGTGCAGCAGGCGATGGTCGATTGCCA
CGGTTCGCAATGCGGGTTCTGCACGCCCGGCTTCGTGATGTCGATGTGGGCGCTGTACGAGAAGCACGGCCACGAAGGCT
GCGGCAGTGCGTGCGCGAAGGCGAAGGACGTGCCGACGCGCACCGAGATTGCCGATGCGCTGACCGGCAACCTGTGTCGC
TGCACCGGCTATCGCCCGATCGTCGATGCGGCGGTGCGGATGTTCGATGCGACCGGCGAAGGCGCGACCGGCGAAGGTGC
TCAGGCACCGTCGGCGCCGGTCGACACGGCCGCGCTCGCCCGCACGCTTGCATCGCTCAAGCGCGACGACACGTTCGACT
ACACGACGATCGACGGCGCGCGCTTCGCGGCGCCGCGCACGCTCGACGCGCTGGCCGCGCTGAAGGCGGAGCGCCCCGAC
GCGCGCATCCTCGCCGGCAGCACCGACATCGGCCTGTGGGTCACCAAGCAGATGCGCCGCCTCGACGACCTGATCTACGT
CGGCCAGATCGCCGAACTGCAGCAGGTCGTGCACGGCGACGACTGGATCGAGATCGGCGCGGGCGTGACGGTCGAGAAGG
CCTATGCGGCGCTGGCCGGCACGTATCCGGAGCTGACCGAGATGTGGAAGCGCTTCGCGTCGCTGCCGATCCGCAATGCG
GGCACGCTCGGCGGCAACGTCGCGAACGGCTCGCCGATCGGCGATTCGATGCCGGGCCTGATCGCGCTCGGCGCGCGCGT
CGTGCTGCGCGGCGGCGACACGGTGCGCGAGCTGCCGCTCGAGGCGCTCTATACGGGCTACCAGCAGAAGGACATGGCGC
CGCACGAATTCGTCGTCGGCCTGAAGGTGCCGACCCGCACCGGCGCGCGCGACAAGCTGCAGTTCCGCACGTACAAGCTG
TCGAAGCGCTTCGACTCGGACATCTCGGCCGTGTGTGCGGCGTTCGCGTTCATCGCGGACGGCGACACGATCCGCGAGCC
GCGCATCGCGTTCGGCGGAATGGCCGCGACGCCGAAGCGCGCGGCCAATACGGAAGCCGTGCTCGACGGCGCGCAGTGGC
ACGAAGCCACCGCGCAGGCCGCGATGCAGGCGCTCGAGCGCGACTACCAGCCGTTGTCCGACATGCGCGCGACGAGCACG
TATCGGCTCGATACCGCGAAGAACCTGATGTATCGATTCTGGCTGGAGACGCGTCCGCACGACCCGTTGCCGCCGCAAGC
CTTGAATGTGCGCGAAGTGGCCGCCGAAGTCGCCGCTGAAGCGGCCAACGACGCGGCGCGCGTCTGA

Upstream 100 bases:

>100_bases
TTGCGGAATTTGACGGTGATAGCGTGCAAACTGTCAGAAAAACGTCGGTCGAGCGCTCCGCGCAGGCCGCCTTGCCCCCC
ATTTGAAGAAACGCCGAGAC

Downstream 100 bases:

>100_bases
CGAGGGAGAACACCGAACATGAACCAGCAAGCAGAACCGTTCCTGAGCACCCTCGATCCGCAGGCCGACGCCGCGCAGGT
GCACGTGTCGCGCGCCCACG

Product: 2Fe-2S ferredoxin, iron-sulfur binding site

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDAGAVEFKAVNACIQFLPTLDG
KALLTVEDLRQPDGTLHPVQQAMVDCHGSQCGFCTPGFVMSMWALYEKHGHEGCGSACAKAKDVPTRTEIADALTGNLCR
CTGYRPIVDAAVRMFDATGEGATGEGAQAPSAPVDTAALARTLASLKRDDTFDYTTIDGARFAAPRTLDALAALKAERPD
ARILAGSTDIGLWVTKQMRRLDDLIYVGQIAELQQVVHGDDWIEIGAGVTVEKAYAALAGTYPELTEMWKRFASLPIRNA
GTLGGNVANGSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQQKDMAPHEFVVGLKVPTRTGARDKLQFRTYKL
SKRFDSDISAVCAAFAFIADGDTIREPRIAFGGMAATPKRAANTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATST
YRLDTAKNLMYRFWLETRPHDPLPPQALNVREVAAEVAAEAANDAARV

Sequences:

>Translated_528_residues
MSEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDAGAVEFKAVNACIQFLPTLDG
KALLTVEDLRQPDGTLHPVQQAMVDCHGSQCGFCTPGFVMSMWALYEKHGHEGCGSACAKAKDVPTRTEIADALTGNLCR
CTGYRPIVDAAVRMFDATGEGATGEGAQAPSAPVDTAALARTLASLKRDDTFDYTTIDGARFAAPRTLDALAALKAERPD
ARILAGSTDIGLWVTKQMRRLDDLIYVGQIAELQQVVHGDDWIEIGAGVTVEKAYAALAGTYPELTEMWKRFASLPIRNA
GTLGGNVANGSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQQKDMAPHEFVVGLKVPTRTGARDKLQFRTYKL
SKRFDSDISAVCAAFAFIADGDTIREPRIAFGGMAATPKRAANTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATST
YRLDTAKNLMYRFWLETRPHDPLPPQALNVREVAAEVAAEAANDAARV
>Mature_527_residues
SEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDAGAVEFKAVNACIQFLPTLDGK
ALLTVEDLRQPDGTLHPVQQAMVDCHGSQCGFCTPGFVMSMWALYEKHGHEGCGSACAKAKDVPTRTEIADALTGNLCRC
TGYRPIVDAAVRMFDATGEGATGEGAQAPSAPVDTAALARTLASLKRDDTFDYTTIDGARFAAPRTLDALAALKAERPDA
RILAGSTDIGLWVTKQMRRLDDLIYVGQIAELQQVVHGDDWIEIGAGVTVEKAYAALAGTYPELTEMWKRFASLPIRNAG
TLGGNVANGSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQQKDMAPHEFVVGLKVPTRTGARDKLQFRTYKLS
KRFDSDISAVCAAFAFIADGDTIREPRIAFGGMAATPKRAANTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATSTY
RLDTAKNLMYRFWLETRPHDPLPPQALNVREVAAEVAAEAANDAARV

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=522, Percent_Identity=29.5019157088123, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI71773480, Length=476, Percent_Identity=26.6806722689076, Blast_Score=158, Evalue=1e-38,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=37.8048780487805, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789231, Length=284, Percent_Identity=26.056338028169, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=37.4149659863946, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=551, Percent_Identity=29.038112522686, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI32566215, Length=479, Percent_Identity=26.3048016701461, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=480, Percent_Identity=26.875, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17737937, Length=504, Percent_Identity=32.5396825396825, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24647201, Length=501, Percent_Identity=27.5449101796407, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24647197, Length=530, Percent_Identity=27.7358490566038, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24647199, Length=499, Percent_Identity=28.8577154308617, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24647193, Length=507, Percent_Identity=28.5996055226824, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24647195, Length=346, Percent_Identity=30.635838150289, Blast_Score=145, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 56872; Mature: 56741

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00059 ADH_ZINC ; PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDA
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GAVEFKAVNACIQFLPTLDGKALLTVEDLRQPDGTLHPVQQAMVDCHGSQCGFCTPGFVM
CCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
SMWALYEKHGHEGCGSACAKAKDVPTRTEIADALTGNLCRCTGYRPIVDAAVRMFDATGE
HHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCC
GATGEGAQAPSAPVDTAALARTLASLKRDDTFDYTTIDGARFAAPRTLDALAALKAERPD
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHCCCHHHHHHHHHHCCCCC
ARILAGSTDIGLWVTKQMRRLDDLIYVGQIAELQQVVHGDDWIEIGAGVTVEKAYAALAG
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHC
TYPELTEMWKRFASLPIRNAGTLGGNVANGSPIGDSMPGLIALGARVVLRGGDTVRELPL
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCHHHHCCH
EALYTGYQQKDMAPHEFVVGLKVPTRTGARDKLQFRTYKLSKRFDSDISAVCAAFAFIAD
HHHHCCCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GDTIREPRIAFGGMAATPKRAANTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATST
CCCCCCCCHHCCCCCCCCCHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCE
YRLDTAKNLMYRFWLETRPHDPLPPQALNVREVAAEVAAEAANDAARV
EECHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GAVEFKAVNACIQFLPTLDGKALLTVEDLRQPDGTLHPVQQAMVDCHGSQCGFCTPGFVM
CCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
SMWALYEKHGHEGCGSACAKAKDVPTRTEIADALTGNLCRCTGYRPIVDAAVRMFDATGE
HHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCC
GATGEGAQAPSAPVDTAALARTLASLKRDDTFDYTTIDGARFAAPRTLDALAALKAERPD
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHCCCHHHHHHHHHHCCCCC
ARILAGSTDIGLWVTKQMRRLDDLIYVGQIAELQQVVHGDDWIEIGAGVTVEKAYAALAG
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHC
TYPELTEMWKRFASLPIRNAGTLGGNVANGSPIGDSMPGLIALGARVVLRGGDTVRELPL
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCHHHHCCH
EALYTGYQQKDMAPHEFVVGLKVPTRTGARDKLQFRTYKLSKRFDSDISAVCAAFAFIAD
HHHHCCCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GDTIREPRIAFGGMAATPKRAANTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATST
CCCCCCCCHHCCCCCCCCCHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCE
YRLDTAKNLMYRFWLETRPHDPLPPQALNVREVAAEVAAEAANDAARV
EECHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]