Click here to switch to the map view.

The map label for this gene is xdhA [H]

Identifier: 116688856

GI number: 116688856

Start: 935213

End: 937576

Strand: Direct

Name: xdhA [H]

Synonym: Bcen2424_0833

Alternate gene names: 116688856

Gene position: 935213-937576 (Clockwise)

Preceding gene: 116688855

Following gene: 116688857

Centisome position: 26.84

GC content: 68.91

Gene sequence:

>2364_bases
ATGAACCAGCAAGCAGAACCGTTCCTGAGCACCCTCGATCCGCAGGCCGACGCCGCGCAGGTGCACGTGTCGCGCGCCCA
CGAATCCGCCCACCTGCACGTGAGCGGGCGCGCCACCTACACCGACGACATTCCGCTCGTCGCCGGCACGCTGCACGCGG
CGCTCGGGTTGTCGGCGAAGCCGCACGCGAAGATCGTCTCGATGAACTTCGACGCGGTGCGCGCGACGCCGGGCGTGGTC
GCCGTGTTCACGGCCGACGACATCCCGGGCGTCAACGATTGCGGCCCGATCATCCACGACGATCCGGTGCTCGCGAAGGG
CGTCGTGCAGTTCGTCGGCCAGCCGATGTTCATCGTCGTCGCGACGTCGCACGAAACCGCGCGGCTCGCCGCGCGCCGCG
CGCAGGTCGACTACGAGGAGTTGCCGGCGATCCTGACCGCGCAGGAAGCGCGCAAGGCCGAAACCTACGTGATCCCGCCG
CTGAAGCTCGCACGCGGCGATGCCGCCGCGCGGCTCGCCGTCGCGCCGCACCGCGAGTCGGGCGAGATGCTGCTCGGCGG
GCAGGAGCAGTTCTACCTCGAAGGGCAGATCGCGTACGCGGTGCCGAAGGACGACGACGGGATGCACGTGTACTGCTCGA
CGCAGCACCCGAGCGAGATGCAGCACCTCGTCGCGCACGTGCTCGGCGTCGCGTCGCACAACGTGCTGGTCGAATGCCGC
CGGATGGGCGGCGGCTTCGGCGGCAAGGAATCGCAGTCGGGGCTGTTCGCGTGTTGCGCGGCGCTCGCCGCATGGAAGCT
GCTGTGCCCGGTGAAGCTGCGCCCGGACCGCGACGACGACATGATGATCACCGGCAAGCGGCACGACTTCCATTACCGCT
TCGACGTCGGCTACGACGACGATGGCCGCATCGACGGCGTCGCGCTCGACATGACGTCGCGCTGCGGCTTCTCGGCCGAT
CTGTCCGGCCCGGTGATGACGCGCGCGGTGTGCCACTTCGACAACGCGTACTGGCTCGGCGACGTCGACATCGCCGGCTA
CTGCGGCAAGACCAACACGCAGTCGAACACCGCGTTCCGCGGCTTCGGCGGCCCGCAGGGCGCGTTCGCGATCGAATACA
TCCTCGACGACATCGCGCGTTCGCTCGGCCGCGATCCGCTCGACGTCCGCTACGCGAACCTGTACGGCAAGACCGAACGC
AACGTGACGCCGTACGGGCAGACGGTCGAGGACAACGTGCTGCAGGAGTTGCTCGGCGAACTCGAGACGACGAGCGACTA
CCGTGCGCGGCGCGCGGGCGTGCGCGCCTTCAACGCACGCAACACGGTGCTGAAGAAGGGCATCGCGCTCACGCCGGTGA
AGTTCGGCATCGCGTTCAACGTCACGCACTTCAACCAGGCCGGCGCGCTGGTGCACATCTACACCGACGGCTCGGTGCTC
GTGAACCACGGCGGCACGGAGATGGGGCAGGGGCTCAACACGAAGGTCGCGCAGGTGGTCGCGCATGAGCTCGGCATCCG
CTTCGGCCGGATCCGCGTGACGGCGACCGACACGAGCAAGGTCGCGAACACGTCCGCGACGGCGGCGTCGACGGGCTCGG
ACCTGAACGGCAAGGCCGCGCAGGATGCGGCGCGCCAGTTGCGCGAGCGGCTCGCGGTGTTCGCGGCGAAGCAGTTCGGC
GACGGCAAGGTTGACGCGGCCGACGTGAAGTTCGGCAACGACGTCGTGTGGGTCGGCGGTCATGGCGTGCCGTTCGGCGA
GGTGATCGCGAAGGCGTACCTCGCGCGTGTGCAGCTGTGGTCCGACGGTTTCTATGCGACGCCGAAGCTGCACTGGGATC
AATCGAAGCTGCAGGGCCGGCCGTTCTACTACTACTCGTACGGCGCGGCCGTGTCGGAAGTCGTGATCGACACGCTGACC
GGCGAAATGCGCACGCTGCGCGTCGATGCGCTGCACGACGTGGGCGCGTCGCTGAACCCGGCGCTCGACATCGGTCAGGT
CGAAGGCGCGTTCATCCAGGGGATGGGCTGGCTGACGACCGAGGAGCTGTGGTGGAACCCGGGCGGCAAGCTGATGACGC
ACGCGCCGTCCACATACAAGATCCCGACGGTGAACGACACGCCGCCCGAGTTCAACGTGCGGCTGTTCCAGAACCGCAAC
GTCGAGGACAGCATCCACCGCTCGAAGGCGGTCGGCGAGCCGCCGCTGCTGCTGCCGTTCTCGGTGTTCTTCGCGGTGCG
CGACGCCGTGGCCGCGGTCGGCGACTATCGCGTGAATCCGCCGCTCGACGCGCCGGCCACCGGCGAGTCGATCCTGCGCG
CGATCGGCGCGGTGCGTGCGGCGAGCGCCGCGCGGGCAGGCTGA

Upstream 100 bases:

>100_bases
GTTGCCGCCGCAAGCCTTGAATGTGCGCGAAGTGGCCGCCGAAGTCGCCGCTGAAGCGGCCAACGACGCGGCGCGCGTCT
GACGAGGGAGAACACCGAAC

Downstream 100 bases:

>100_bases
GATGAACCGCCTCTCCACGCTCGCTTCGTGCGCCGGCCCCGACGGGGCGGTCAGCCTCGTCGTCAGGCCGGCCCGGCGGA
GGCCGGCATGAACGGCCCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHAKIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIIHDDPVLAKGVVQFVGQPMFIVVATSHETARLAARRAQVDYEELPAILTAQEARKAETYVIPP
LKLARGDAAARLAVAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDDDGRIDGVALDMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARSLGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLQELLGELETTSDYRARRAGVRAFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQFG
DGKVDAADVKFGNDVVWVGGHGVPFGEVIAKAYLARVQLWSDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNPGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAVAAVGDYRVNPPLDAPATGESILRAIGAVRAASAARAG

Sequences:

>Translated_787_residues
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHAKIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIIHDDPVLAKGVVQFVGQPMFIVVATSHETARLAARRAQVDYEELPAILTAQEARKAETYVIPP
LKLARGDAAARLAVAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDDDGRIDGVALDMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARSLGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLQELLGELETTSDYRARRAGVRAFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQFG
DGKVDAADVKFGNDVVWVGGHGVPFGEVIAKAYLARVQLWSDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNPGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAVAAVGDYRVNPPLDAPATGESILRAIGAVRAASAARAG
>Mature_787_residues
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAKPHAKIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIIHDDPVLAKGVVQFVGQPMFIVVATSHETARLAARRAQVDYEELPAILTAQEARKAETYVIPP
LKLARGDAAARLAVAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDDDGRIDGVALDMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARSLGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLQELLGELETTSDYRARRAGVRAFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQFG
DGKVDAADVKFGNDVVWVGGHGVPFGEVIAKAYLARVQLWSDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNPGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAVAAVGDYRVNPPLDAPATGESILRAIGAVRAASAARAG

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=770, Percent_Identity=42.8571428571429, Blast_Score=584, Evalue=1e-166,
Organism=Homo sapiens, GI71773480, Length=753, Percent_Identity=38.2470119521912, Blast_Score=482, Evalue=1e-136,
Organism=Escherichia coli, GI1789230, Length=751, Percent_Identity=27.5632490013316, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1789246, Length=736, Percent_Identity=26.0869565217391, Blast_Score=183, Evalue=4e-47,
Organism=Escherichia coli, GI1786478, Length=732, Percent_Identity=24.4535519125683, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=762, Percent_Identity=41.2073490813648, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI32566215, Length=708, Percent_Identity=32.4858757062147, Blast_Score=338, Evalue=8e-93,
Organism=Caenorhabditis elegans, GI17539860, Length=722, Percent_Identity=31.8559556786704, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI17737937, Length=759, Percent_Identity=43.2147562582345, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24647193, Length=779, Percent_Identity=32.6059050064185, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24647199, Length=780, Percent_Identity=30.8974358974359, Blast_Score=325, Evalue=8e-89,
Organism=Drosophila melanogaster, GI24647201, Length=766, Percent_Identity=31.0704960835509, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24647195, Length=779, Percent_Identity=30.6803594351733, Blast_Score=290, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24647197, Length=779, Percent_Identity=30.6803594351733, Blast_Score=289, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 84854; Mature: 84854

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAK
CCCCCCCHHHHCCCCCCHHHEEHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHCCCCC
PHAKIVSMNFDAVRATPGVVAVFTADDIPGVNDCGPIIHDDPVLAKGVVQFVGQPMFIVV
CCCEEEEECCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
ATSHETARLAARRAQVDYEELPAILTAQEARKAETYVIPPLKLARGDAAARLAVAPHRES
ECCCHHHHHHHHHHCCCHHHCCHHEEHHHHHCCCEEEECCHHCCCCCCCEEEEECCCCCC
GEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
CCEEECCCCEEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHH
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCEEEEEECCCCC
DGRIDGVALDMTSRCGFSADLSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFR
CCCCCEEEEEEHHCCCCCCCCCCCHHHHHHHCCCCEEEEECCEEECCCCCCCCCCCCEEE
GFGGPQGAFAIEYILDDIARSLGRDPLDVRYANLYGKTERNVTPYGQTVEDNVLQELLGE
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LETTSDYRARRAGVRAFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
HCCCHHHHHHHHCCCEECCCHHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEEE
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAA
EECCCHHHCCCCCHHHHHHHHHHHCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHHH
QDAARQLRERLAVFAAKQFGDGKVDAADVKFGNDVVWVGGHGVPFGEVIAKAYLARVQLW
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHEEE
SDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRTLRVDALHDVGASLNP
CCCEEECCEEECCHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
ALDIGQVEGAFIQGMGWLTTEELWWNPGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
CCCCCCCCCHHEECCCCEEEHHEEECCCCCEEEECCCCEECCCCCCCCCCCEEEEEECCC
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAVAAVGDYRVNPPLDAPATGESILRAIGAVRA
CHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHH
ASAARAG
HHHHCCC
>Mature Secondary Structure
MNQQAEPFLSTLDPQADAAQVHVSRAHESAHLHVSGRATYTDDIPLVAGTLHAALGLSAK
CCCCCCCHHHHCCCCCCHHHEEHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHCCCCC
PHAKIVSMNFDAVRATPGVVAVFTADDIPGVNDCGPIIHDDPVLAKGVVQFVGQPMFIVV
CCCEEEEECCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
ATSHETARLAARRAQVDYEELPAILTAQEARKAETYVIPPLKLARGDAAARLAVAPHRES
ECCCHHHHHHHHHHCCCHHHCCHHEEHHHHHCCCEEEECCHHCCCCCCCEEEEECCCCCC
GEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
CCEEECCCCEEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHH
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMMITGKRHDFHYRFDVGYDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCEEEEEECCCCC
DGRIDGVALDMTSRCGFSADLSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFR
CCCCCEEEEEEHHCCCCCCCCCCCHHHHHHHCCCCEEEEECCEEECCCCCCCCCCCCEEE
GFGGPQGAFAIEYILDDIARSLGRDPLDVRYANLYGKTERNVTPYGQTVEDNVLQELLGE
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LETTSDYRARRAGVRAFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
HCCCHHHHHHHHCCCEECCCHHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEEE
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAA
EECCCHHHCCCCCHHHHHHHHHHHCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHHH
QDAARQLRERLAVFAAKQFGDGKVDAADVKFGNDVVWVGGHGVPFGEVIAKAYLARVQLW
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHEEE
SDGFYATPKLHWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRTLRVDALHDVGASLNP
CCCEEECCEEECCHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
ALDIGQVEGAFIQGMGWLTTEELWWNPGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
CCCCCCCCCHHEECCCCEEEHHEEECCCCCEEEECCCCEECCCCCCCCCCCEEEEEECCC
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAVAAVGDYRVNPPLDAPATGESILRAIGAVRA
CHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHH
ASAARAG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]