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The map label for this gene is ubiA [H]

Identifier: 116688752

GI number: 116688752

Start: 813001

End: 813864

Strand: Direct

Name: ubiA [H]

Synonym: Bcen2424_0729

Alternate gene names: 116688752

Gene position: 813001-813864 (Clockwise)

Preceding gene: 116688751

Following gene: 116688759

Centisome position: 23.34

GC content: 66.09

Gene sequence:

>864_bases
ATGCTTGCCCGCTTTCCCCTGTATCTGCGGCTCGTCCGGATGGACAAGCCGATCGGCAGCCTGCTGCTGCTGTGGCCGAC
GCTCAACGCGCTGTGGATCGCGTCGGACGGCCGCCCGCGCTGGCCGCTGCTCGTGATCTTCACGCTCGGCACGCTGCTGA
TGCGCTCGGCCGGCTGCGCGATGAACGACTACGCCGACCGCGATTTCGACCGCCACGTGAAGCGCACGGCCGACCGGCCG
CTGACGTCGGGCAAGATCCGCGCATGGGAAGCCGTCGCGATCGCGGTGGGGCTGTCGTTCATCGCGTTCCTGCTGATCCT
GCCGCTCAATACGCTGACGAAGGAATTGTCGGTGGTCGCGCTGTTCGTCGCCGGCTCCTACCCGTTTATGAAGCGCTTCT
TCGCGATTCCGCAGGCGTATCTGGGCATCGCGTTCGGCTTCGGCATCCCGATGGCGTTCGCGGCCGTGCAGGATACGGTG
CCGATGCTGGCGTGGGTGATGCTGGTCGCGAACATCTTCTGGTCGGTCGCGTACGACACCGAATATGCGATGGTCGATCG
CGACGACGACATCAAGATCGGCATCCGCACGTCCGCGCTGACGTTCGGCCGTTTCGACGTCGCGGCCGTGATGGCGTGCT
ACGCGGCGACGCTCGGCATCTACGTGTGGATCGGCGTGACGCTCGGCTTCGGCCTCGCGTACTGGGTGGGCTGGGCGGCG
GCGGTCGGCTGTGCGCTCTATCACTACACGCTGATCAAGGATCGCGAACGGATGCCGTGCTTCGCGGCGTTTCGCCACAA
CAACTGGCTGGGCGGCGTGCTGTTCGCGGGCATCGCCGCGCATTACCTGCTGGCGGGCAACTGA

Upstream 100 bases:

>100_bases
CCCGCCGGCCCGCCGCGCCCACCGGCTGAGGGTCGCGCCGACATGACGCAAAGCACCGCTCGGCTCTAAAATGCCGGGAT
TCTCTTCCCGGTGCTTCGCC

Downstream 100 bases:

>100_bases
ACGGCACACCGCGCGTACTTGCGCGCGGCGCCAACGAAAAAGCGACCTGACGGTCGCTTTTTTTTACGTCTCGCGCCGGC
ACGACCGGCGCCGCCGTCGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPRWPLLVIFTLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVGLSFIAFLLILPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMLAWVMLVANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAATLGIYVWIGVTLGFGLAYWVGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGN

Sequences:

>Translated_287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPRWPLLVIFTLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVGLSFIAFLLILPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMLAWVMLVANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAATLGIYVWIGVTLGFGLAYWVGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGN
>Mature_287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPRWPLLVIFTLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVGLSFIAFLLILPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMLAWVMLVANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAATLGIYVWIGVTLGFGLAYWVGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGN

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=275, Percent_Identity=34.5454545454545, Blast_Score=152, Evalue=3e-37,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=54.1818181818182, Blast_Score=276, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=33.2142857142857, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32565247, Length=283, Percent_Identity=32.1554770318021, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17553720, Length=340, Percent_Identity=28.5294117647059, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=38.6861313868613, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=38.3458646616541, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324370, Length=290, Percent_Identity=28.2758620689655, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21355567, Length=289, Percent_Identity=33.9100346020761, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 31885; Mature: 31885

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPRWPLLVIFTLGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVGLSFIAFLLILPLNTLTKELSVVA
CCCHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMLAWVMLVANIFWSVAYDT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAATLGIYVWIGVTLGFGLAYWVGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGN
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPRWPLLVIFTLGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVGLSFIAFLLILPLNTLTKELSVVA
CCCHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMLAWVMLVANIFWSVAYDT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAATLGIYVWIGVTLGFGLAYWVGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGN
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA