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The map label for this gene is ftsW [H]

Identifier: 116688582

GI number: 116688582

Start: 628079

End: 629362

Strand: Direct

Name: ftsW [H]

Synonym: Bcen2424_0558

Alternate gene names: 116688582

Gene position: 628079-629362 (Clockwise)

Preceding gene: 116688581

Following gene: 116688583

Centisome position: 18.03

GC content: 66.51

Gene sequence:

>1284_bases
ATGAGCTGGTCCGATCGCCTCGTCTCCCGCTTCAATGACCGGCGCGACACCGGCGGCAATGCCGCGGGCGGCCGCGTCGC
GTCGGCCACGCGCGCCGCGACGGGCGGCCTCGCGAGCGTCGTCAACGGCGTGCGCCCGAGCCGTTCGCGGATGCTCGATT
TCGACTATTCGCTGCTGTGGGTCGCGATCGCGCTGCTCGGACTCGGCGTCGTGATGGTGTATTCGGCGTCGATCGCGATG
CCCGATTCGCCGAAATACGCGTCGTATCACGATTACGCGTTCCTGATGCGCCACTGCGTGTCGCTCACCGTCGCGTTCAT
CGCGGCGGTGCTCGCGTTCCGCGTGCCGGTGTCGACCTGGGACAAGTACGCGCCGCATCTTTTCCTGATCGCGCTGGTCG
GCCTCGTGATCGTGCTGATCCCGCACGTCGGCAAGGGCGTGAACGGTGCACGCCGCTGGATTCCGCTCGGCATCACGAAC
ATGCAGCCGTCGGAAATCATGAAGCTCGCGGTGACGATCTACGCGGCGAACTACACGGTACGCAAGCAGGAATACATGCA
GAGCTTCGCGAAGGGCTTCCTGCCGATGGCGTTCGCGGTCGGCCTGGTCGGCGCGCTGCTGCTGCTCGAGCCCGACATGG
GCGCGTTCATGGTGGTCGCCGCGATCGCGATGGGCGTGCTGTTCCTCGGCGGCGTGAACGGCAAGTTGTTCGGCGGCCTC
GTCGCGACGGCGGTCGGCACGTTCACGATGCTCGTGTGGCTGTCGCCGTGGCGTCGCGAGCGGATCTTCGCGTATCTCGA
TCCGTGGGACGAGCGCTACGCGCAGGGCAAGGCTTACCAGCTCACGCACTCGCTGATCGCGTTCGGCCGCGGCGAGTGGT
TCGGCGTCGGCCTCGGCGGCAGTGTCGAGAAGCTGAACTACCTGCCGGAAGCGCATACCGACTTCATCCTCGCGGTGATC
GGCGAGGAACTCGGCTTCATCGGCGTGCTGGTCGTGATCCTGCTGTTCTACTGGATCGTGCGTCGCGCGTTCGAGATCGG
CCGCCAGGCGCTCGCGCTCGATCGCACGTTCGCGGGCCTGATGGCGAAGGGCATCGGCATCTGGTTCGGCGCGCAGACGT
TCATCAACATGGGCGTGAACCTCGGGCTGCTGCCGACCAAGGGGCTGACGCTGCCGCTCGTGAGCTATGGCGGCTCCGGC
ATCCTGCTGAACTGTGTCGCGCTCGCGGTGCTGCTGCGGGTCGACTACGAGAACCGGGTGCTGATGCGCGGAGGGAAGGT
ATGA

Upstream 100 bases:

>100_bases
CTGCCTGTGCGAGCCTCGACATGTTCAGGAACTACGCCCATCGCGCGGAAGTGTTCCGCGCGGCGGTCGACGCAATCGCC
ATCGACAAAGGAGCGACGCC

Downstream 100 bases:

>100_bases
CCGCGTCGCAACGCACGCTGATGGTGATGGCAGGCGGCACCGGGGGCCACGTGTTCCCGGGGCTCGCGGTCGCGCACCGG
ATGGAAGCGGCGGGCTGGCG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLWVAIALLGLGVVMVYSASIAM
PDSPKYASYHDYAFLMRHCVSLTVAFIAAVLAFRVPVSTWDKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLGITN
MQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGL
VATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVI
GEELGFIGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSG
ILLNCVALAVLLRVDYENRVLMRGGKV

Sequences:

>Translated_427_residues
MSWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLWVAIALLGLGVVMVYSASIAM
PDSPKYASYHDYAFLMRHCVSLTVAFIAAVLAFRVPVSTWDKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLGITN
MQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGL
VATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVI
GEELGFIGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSG
ILLNCVALAVLLRVDYENRVLMRGGKV
>Mature_426_residues
SWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLWVAIALLGLGVVMVYSASIAMP
DSPKYASYHDYAFLMRHCVSLTVAFIAAVLAFRVPVSTWDKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLGITNM
QPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGLV
ATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIG
EELGFIGVLVVILLFYWIVRRAFEIGRQALALDRTFAGLMAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGI
LLNCVALAVLLRVDYENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=378, Percent_Identity=42.8571428571429, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=31.1953352769679, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46415; Mature: 46284

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCCCCC
>Mature Secondary Structure 
SWSDRLVSRFNDRRDTGGNAAGGRVASATRAATGGLASVVNGVRPSRSRMLDFDYSLLW
CHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCHHHEECCCHHHHH
VAIALLGLGVVMVYSASIAMPDSPKYASYHDYAFLMRHCVSLTVAFIAAVLAFRVPVSTW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
DKYAPHLFLIALVGLVIVLIPHVGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAANYTV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHEECCCCH
RKQEYMQSFAKGFLPMAFAVGLVGALLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
VATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSLIAFGRGEWFGVGLGG
HHHHHHHHHHHHHHCCHHHCCEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCC
SVEKLNYLPEAHTDFILAVIGEELGFIGVLVVILLFYWIVRRAFEIGRQALALDRTFAGL
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKGIGIWFGAQTFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCVALAVLLRVDYENRV
HHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEE
LMRGGKV
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]