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The map label for this gene is trpD [H]

Identifier: 116688556

GI number: 116688556

Start: 592211

End: 593278

Strand: Reverse

Name: trpD [H]

Synonym: Bcen2424_0532

Alternate gene names: 116688556

Gene position: 593278-592211 (Counterclockwise)

Preceding gene: 116688557

Following gene: 116688555

Centisome position: 17.03

GC content: 66.29

Gene sequence:

>1068_bases
ATGCCGCCGCACCGGCTGCCTGACGAGAGACGCACGATGACGATTACCCCGCAGGAAGCGCTGCAGCGCACGATCGAGCA
CCGCGAGATCTTCCACGACGAAATGCTGCACCTGATGCGGCTGATCATGCGCGGCGACCTGTCGCCCGTGATGGCGGCCG
CGATCATCACCGGGCTGCGCGTGAAGAAGGAGACGATCGGCGAGATCGCCGCCGCCGCGACCGTGATGCGCGAATTCGCG
AATCACGTCGAGGTGCAGGACAATTCGAATTTCGTCGACATCGTCGGCACCGGCGGCGACGGCTCGCACACGTTCAACAT
CTCGACCGCGTCGATGTTCGTCACGGCGGCCGCGGGCGCGAAGGTCGCGAAGCACGGCAACCGCGGCGTATCGAGCAAGT
CCGGCAGCGCCGACGTACTCGAGGCGCTCGGCGTGAACATCGACCTGCAGTCGGAGCAAGTCGCCGCATCGATCGCCGAA
ACCGGCATGGGCTTCATGTTCGCGCCGAACCATCACCCGGCGATGAAGAACATCGCGGCCGTGCGCCGCGAGCTCGGCGT
GCGCACGATCTTCAACATCCTCGGCCCGCTGACCAATCCGGCCGGCGCACCGAACCAGCTGATGGGCGTTTTCCACCCCG
ACCTCGTCGGCATCCAGGTGCGCGTGATGCAGCGTCTCGGCGCGCAGCACGTGCTCGTCGTGTACGGCAAGGACGGGATG
GACGAGGTGTCGCTCGGCGCCGCGACGCTCGTCGGCGAATTGCGCGACGGCAAGGTGCACGAATACGAGATCCATCCGGA
GGACTTCGGCCTGCAGATGGTGTCGAACCGCACGCTGAAGGTGGAAAATGCCGACGAATCGCGCACGATGCTGCTCGGCG
CGCTGGACAACCAGCCGGGCGTCGCGCGCGAGATCGTCACGCTGAACGCGGGCACCGCGCTCTACGCGGCCAATATCGCC
GAATCGATCGCGGACGGCATCCAGCTCGCCCGCGAAGCGATCGCGAGCGGCAAGGCCCGCGCGAAGGTCGACGAACTCGT
GCGCTTCACGCAGCAATTCAAGCGCTGA

Upstream 100 bases:

>100_bases
CTGCCGGTCGAAGGCGTGCAGTTCCACCCGGAATCGATTCTCTCGGAGCATGGCCATGCGCTGCTCGAGAATTTCCTGAA
GCAGCATCGCGCGGCGGCCC

Downstream 100 bases:

>100_bases
CCCTCTTACGAATCCAGCAGGAACCCCTATGAGCGACATTCTCGACCGAATCATCGCCGTCAAGCGCGAAGAAATCGCGG
CGGCCCTGCGCAGCACGCCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MPPHRLPDERRTMTITPQEALQRTIEHREIFHDEMLHLMRLIMRGDLSPVMAAAIITGLRVKKETIGEIAAAATVMREFA
NHVEVQDNSNFVDIVGTGGDGSHTFNISTASMFVTAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQSEQVAASIAE
TGMGFMFAPNHHPAMKNIAAVRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGM
DEVSLGAATLVGELRDGKVHEYEIHPEDFGLQMVSNRTLKVENADESRTMLLGALDNQPGVAREIVTLNAGTALYAANIA
ESIADGIQLAREAIASGKARAKVDELVRFTQQFKR

Sequences:

>Translated_355_residues
MPPHRLPDERRTMTITPQEALQRTIEHREIFHDEMLHLMRLIMRGDLSPVMAAAIITGLRVKKETIGEIAAAATVMREFA
NHVEVQDNSNFVDIVGTGGDGSHTFNISTASMFVTAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQSEQVAASIAE
TGMGFMFAPNHHPAMKNIAAVRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGM
DEVSLGAATLVGELRDGKVHEYEIHPEDFGLQMVSNRTLKVENADESRTMLLGALDNQPGVAREIVTLNAGTALYAANIA
ESIADGIQLAREAIASGKARAKVDELVRFTQQFKR
>Mature_354_residues
PPHRLPDERRTMTITPQEALQRTIEHREIFHDEMLHLMRLIMRGDLSPVMAAAIITGLRVKKETIGEIAAAATVMREFAN
HVEVQDNSNFVDIVGTGGDGSHTFNISTASMFVTAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQSEQVAASIAET
GMGFMFAPNHHPAMKNIAAVRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMD
EVSLGAATLVGELRDGKVHEYEIHPEDFGLQMVSNRTLKVENADESRTMLLGALDNQPGVAREIVTLNAGTALYAANIAE
SIADGIQLAREAIASGKARAKVDELVRFTQQFKR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=331, Percent_Identity=40.1812688821752, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=356, Percent_Identity=26.9662921348315, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 38308; Mature: 38177

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPHRLPDERRTMTITPQEALQRTIEHREIFHDEMLHLMRLIMRGDLSPVMAAAIITGLR
CCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VKKETIGEIAAAATVMREFANHVEVQDNSNFVDIVGTGGDGSHTFNISTASMFVTAAAGA
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHCCC
KVAKHGNRGVSSKSGSADVLEALGVNIDLQSEQVAASIAETGMGFMFAPNHHPAMKNIAA
HHHHCCCCCCCCCCCCHHHHHHHCCCCEECHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
VRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGM
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
DEVSLGAATLVGELRDGKVHEYEIHPEDFGLQMVSNRTLKVENADESRTMLLGALDNQPG
CHHHHHHHHHHHHHCCCCEEEEEECCHHCCCEEECCCEEEEECCCCCCEEEEEECCCCCC
VAREIVTLNAGTALYAANIAESIADGIQLAREAIASGKARAKVDELVRFTQQFKR
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPHRLPDERRTMTITPQEALQRTIEHREIFHDEMLHLMRLIMRGDLSPVMAAAIITGLR
CCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VKKETIGEIAAAATVMREFANHVEVQDNSNFVDIVGTGGDGSHTFNISTASMFVTAAAGA
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHCCC
KVAKHGNRGVSSKSGSADVLEALGVNIDLQSEQVAASIAETGMGFMFAPNHHPAMKNIAA
HHHHCCCCCCCCCCCCHHHHHHHCCCCEECHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
VRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGM
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
DEVSLGAATLVGELRDGKVHEYEIHPEDFGLQMVSNRTLKVENADESRTMLLGALDNQPG
CHHHHHHHHHHHHHCCCCEEEEEECCHHCCCEEECCCEEEEECCCCCCEEEEEECCCCCC
VAREIVTLNAGTALYAANIAESIADGIQLAREAIASGKARAKVDELVRFTQQFKR
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA