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The map label for this gene is trpC [H]

Identifier: 116688555

GI number: 116688555

Start: 591397

End: 592182

Strand: Reverse

Name: trpC [H]

Synonym: Bcen2424_0531

Alternate gene names: 116688555

Gene position: 592182-591397 (Counterclockwise)

Preceding gene: 116688556

Following gene: 116688554

Centisome position: 17.0

GC content: 66.92

Gene sequence:

>786_bases
ATGAGCGACATTCTCGACCGAATCATCGCCGTCAAGCGCGAAGAAATCGCGGCGGCCCTGCGCAGCACGCCGCTCGAGGC
ACTGAAACTGGAAGCCTCGGCGCGCGACCTGCGCGACTTCGTCGGCGCGCTGCGCGCGAAGCACGCGGCCGGCAACGCCG
CCGTGATCGCCGAAATCAAGAAGGCCAGCCCGTCGAAAGGCGTGCTGCGCGAGCATTTCGTGCCGGCCGACATCGCGCGC
TCGTATGCGGCGCACGGCGCCGCGTGCCTGTCGGTGCTGACCGACGAGCAGTTCTTCCAGGGCGGCGTCCGCTATCTCGA
GGAAGCGCGCGCGGCCTGCACGCTGCCGGTGCTGCGCAAGGACTTCATCGTCGACGCGTACCAGATCGTCGAAGCCCGCG
CGATGGGCGCCGATGCGATCCTGCTGATCGCCGCCGCACTCGACACGCCGCTGATGCAGGATCTCGAAGCGTATGCGCAC
TCGCTCGGCCTCGCGGTGCTGGTCGAAGTGCACGACCGCCACGAGATGGAACAGGCGCTGACGCTGAAGACGCCGCTGCT
CGGCATCAACAACCGCAACCTGCGCACGTTCGAGACGTCGATCCAGACCACGCTCGACATGCTCGACATGATTCCGGCGG
ATCGCATCGTCGTGACCGAATCGGGCATCCTGTCGCGCACCGACGTCGACACGATGCGCGCGGCGAACGTGAACACGTTC
CTCGTCGGCGAGGCGTTCATGCGCGCCGAGCAGCCGGGCGAGGAACTCGCACGGATGTTCTTCTGA

Upstream 100 bases:

>100_bases
GCGATCGCGAGCGGCAAGGCCCGCGCGAAGGTCGACGAACTCGTGCGCTTCACGCAGCAATTCAAGCGCTGACCCTCTTA
CGAATCCAGCAGGAACCCCT

Downstream 100 bases:

>100_bases
TGGCGATCGAACAGGAAATCAAGCTCGCGCTGCCGGCCGGCCAGGCCGACGCCGCGCGCCGCTTCTTCGAGACGCTGACC
GGCGAACCCGGCCGTGCCAT

Product: indole-3-glycerol-phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSDILDRIIAVKREEIAAALRSTPLEALKLEASARDLRDFVGALRAKHAAGNAAVIAEIKKASPSKGVLREHFVPADIAR
SYAAHGAACLSVLTDEQFFQGGVRYLEEARAACTLPVLRKDFIVDAYQIVEARAMGADAILLIAAALDTPLMQDLEAYAH
SLGLAVLVEVHDRHEMEQALTLKTPLLGINNRNLRTFETSIQTTLDMLDMIPADRIVVTESGILSRTDVDTMRAANVNTF
LVGEAFMRAEQPGEELARMFF

Sequences:

>Translated_261_residues
MSDILDRIIAVKREEIAAALRSTPLEALKLEASARDLRDFVGALRAKHAAGNAAVIAEIKKASPSKGVLREHFVPADIAR
SYAAHGAACLSVLTDEQFFQGGVRYLEEARAACTLPVLRKDFIVDAYQIVEARAMGADAILLIAAALDTPLMQDLEAYAH
SLGLAVLVEVHDRHEMEQALTLKTPLLGINNRNLRTFETSIQTTLDMLDMIPADRIVVTESGILSRTDVDTMRAANVNTF
LVGEAFMRAEQPGEELARMFF
>Mature_260_residues
SDILDRIIAVKREEIAAALRSTPLEALKLEASARDLRDFVGALRAKHAAGNAAVIAEIKKASPSKGVLREHFVPADIARS
YAAHGAACLSVLTDEQFFQGGVRYLEEARAACTLPVLRKDFIVDAYQIVEARAMGADAILLIAAALDTPLMQDLEAYAHS
LGLAVLVEVHDRHEMEQALTLKTPLLGINNRNLRTFETSIQTTLDMLDMIPADRIVVTESGILSRTDVDTMRAANVNTFL
VGEAFMRAEQPGEELARMFF

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=247, Percent_Identity=39.2712550607287, Blast_Score=151, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322638, Length=261, Percent_Identity=36.3984674329502, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 28545; Mature: 28414

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDILDRIIAVKREEIAAALRSTPLEALKLEASARDLRDFVGALRAKHAAGNAAVIAEIK
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KASPSKGVLREHFVPADIARSYAAHGAACLSVLTDEQFFQGGVRYLEEARAACTLPVLRK
HCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFIVDAYQIVEARAMGADAILLIAAALDTPLMQDLEAYAHSLGLAVLVEVHDRHEMEQAL
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
TLKTPLLGINNRNLRTFETSIQTTLDMLDMIPADRIVVTESGILSRTDVDTMRAANVNTF
HHHCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCEE
LVGEAFMRAEQPGEELARMFF
EHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
SDILDRIIAVKREEIAAALRSTPLEALKLEASARDLRDFVGALRAKHAAGNAAVIAEIK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KASPSKGVLREHFVPADIARSYAAHGAACLSVLTDEQFFQGGVRYLEEARAACTLPVLRK
HCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFIVDAYQIVEARAMGADAILLIAAALDTPLMQDLEAYAHSLGLAVLVEVHDRHEMEQAL
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
TLKTPLLGINNRNLRTFETSIQTTLDMLDMIPADRIVVTESGILSRTDVDTMRAANVNTF
HHHCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCEE
LVGEAFMRAEQPGEELARMFF
EHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA