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The map label for this gene is ung [H]

Identifier: 116688553

GI number: 116688553

Start: 589840

End: 590757

Strand: Reverse

Name: ung [H]

Synonym: Bcen2424_0529

Alternate gene names: 116688553

Gene position: 590757-589840 (Counterclockwise)

Preceding gene: 116688554

Following gene: 116688548

Centisome position: 16.96

GC content: 71.46

Gene sequence:

>918_bases
ATGGCAACCCGCAAGACTTCCCGCGCGCCGCAACAGGCGTCGCTGTTCGACGATCCCGTGCCGGAAACGGCACCGGCCGA
TATTCCGTCCCCGGCTTCCGAGCCGCCGGCGGCCGGGCGCAAACCCGCGAAGAAAACCGCCGCACCGGCGCCCGCAGCAG
CCCCGGCCGCCGCGGTACTGCGGCCCGTTGCCGCCGACGTGCCGCATCTGGCCGAACAATTCGACGCGCTGCCGGCCGTC
TGGCGCGACGTGCTGAAACCGTTCACCGACAGCGACGCGTACGCACCGCTGTGCCGCTTCGTCGATGAAGAGCGTGCGGC
CGGCAAGACGGTCTACCCGACCGACGTGTTCCGCGCGCTGCGCCTGACGCATCCCGACGACGTGAAGGTCGTGATCCTCG
GCCAGGACCCGTACCACGGCGACGACCGCGGCACGCCGCAGGCGCACGGCCTCGCGTTCTCGGTGCCGCCGGCCGTGCGC
ACGCCGCCGTCGCTGCGCAACATCTTCAAGGAAATCGCCGCGAACTTCGGTCACGACACGCCGCGTCACGGCTGCCTCGA
CACGTGGGCACGCCAGGGCGTGCTGCTGCTCAACACCGTGCTGACGGTCGAGCGCGGCGCGGCCGCGAGCCATGCGAAGC
GCGGCTGGGAGCAATGCACGGACACGCTGATCCGCGAGCTCGCCGGCCGTCATCGCGGGCTCGTGTTCATGCTGTGGGGC
GCGCACGCGCAGGCCAAGCGCGCGCTGTTCGACGCGAACGCGCATTGCGTGCTCGAGGCGCCGCATCCGTCGCCGCTGTC
CGCGCACCGCGGCTTCCTCGGCTGCCGCCATTTCGCGCTCGCGAACGACTATCTGGCCGCTGCCGGCCGCGAACCGATCG
ACTGGCGCCTGCCGGACGTAGCCGAAACGCTCGCGTAA

Upstream 100 bases:

>100_bases
GCCGCCGAACTGCAGCAGGCACTGCCGGGCCTCGTTCCCGAAAACATCAGCAAGGCGCAGCGCGGCTACCGGCTGCGCGC
GCAATAAACTCGCATCACGC

Downstream 100 bases:

>100_bases
CAGCCTCGGTTGCGGCGAGTTCGCCGGCCGAATGCAAAAACGCCGCGTCCCCGAAAGGACGCGGCGTTTTTTTCATCGGG
CGACGCAGCGGGTGCATCGC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MATRKTSRAPQQASLFDDPVPETAPADIPSPASEPPAAGRKPAKKTAAPAPAAAPAAAVLRPVAADVPHLAEQFDALPAV
WRDVLKPFTDSDAYAPLCRFVDEERAAGKTVYPTDVFRALRLTHPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVR
TPPSLRNIFKEIAANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWG
AHAQAKRALFDANAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLAAAGREPIDWRLPDVAETLA

Sequences:

>Translated_305_residues
MATRKTSRAPQQASLFDDPVPETAPADIPSPASEPPAAGRKPAKKTAAPAPAAAPAAAVLRPVAADVPHLAEQFDALPAV
WRDVLKPFTDSDAYAPLCRFVDEERAAGKTVYPTDVFRALRLTHPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVR
TPPSLRNIFKEIAANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWG
AHAQAKRALFDANAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLAAAGREPIDWRLPDVAETLA
>Mature_304_residues
ATRKTSRAPQQASLFDDPVPETAPADIPSPASEPPAAGRKPAKKTAAPAPAAAPAAAVLRPVAADVPHLAEQFDALPAVW
RDVLKPFTDSDAYAPLCRFVDEERAAGKTVYPTDVFRALRLTHPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRT
PPSLRNIFKEIAANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWGA
HAQAKRALFDANAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLAAAGREPIDWRLPDVAETLA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=221, Percent_Identity=49.7737556561086, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI6224979, Length=221, Percent_Identity=49.7737556561086, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1788934, Length=218, Percent_Identity=55.045871559633, Blast_Score=235, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17556304, Length=219, Percent_Identity=43.37899543379, Blast_Score=187, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6323620, Length=250, Percent_Identity=41.2, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 32874; Mature: 32743

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRKTSRAPQQASLFDDPVPETAPADIPSPASEPPAAGRKPAKKTAAPAPAAAPAAAVL
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHH
RPVAADVPHLAEQFDALPAVWRDVLKPFTDSDAYAPLCRFVDEERAAGKTVYPTDVFRAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RLTHPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSLRNIFKEIAANFGHDT
HCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
PRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWG
CCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
AHAQAKRALFDANAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLAAAGREPIDWRLPDV
CCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
AETLA
HHHCC
>Mature Secondary Structure 
ATRKTSRAPQQASLFDDPVPETAPADIPSPASEPPAAGRKPAKKTAAPAPAAAPAAAVL
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHH
RPVAADVPHLAEQFDALPAVWRDVLKPFTDSDAYAPLCRFVDEERAAGKTVYPTDVFRAL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RLTHPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSLRNIFKEIAANFGHDT
HCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
PRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWG
CCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
AHAQAKRALFDANAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLAAAGREPIDWRLPDV
CCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
AETLA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA