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The map label for this gene is pepQ [H]

Identifier: 116688538

GI number: 116688538

Start: 572123

End: 573937

Strand: Direct

Name: pepQ [H]

Synonym: Bcen2424_0514

Alternate gene names: 116688538

Gene position: 572123-573937 (Clockwise)

Preceding gene: 116688537

Following gene: 116688539

Centisome position: 16.42

GC content: 70.63

Gene sequence:

>1815_bases
ATGAATGCCCGTCTCCCCGAAGTCTCGCCGGTGCCGGCCCGTCTCGCGCTGTTGCGCGACGCCATGGTCCGCGAGAACCT
GGCCGCTTATCTCGTGCCGTCCGCCGATCCCCATCTGTCCGAATACCTGCCCGAACGCTGGCAGGCGCGCCGCTGGCTGT
CCGGCTTCACGGGCTCGGTCGGCACGCTGGTCGTGACCGCGGATTTCGCGGGGTTGTGGGTCGACAGCCGCTACTGGGTG
CAGGCCGACGCCGAGCTGGCGGGCACGGGCGTGCAGCTGATGAAGATGACGGGCGGGCAGCAGAGCGCACCGCACGTCGA
CTGGCTCGCGCAGAACGTGGCGGCCGGCGCGACGGTCGGGGTCGACGGCGCGGTGCTCGGCGTCGCGGCCGCGCGCGGGC
TGACGGCCGCGCTGAGCGCGCGCGGCATCGCGCTGCGTACCGACGTCGACCTGCTCGACGCGATCTGGCCCGAGCGGCCG
GGGCTGCCCGGCGACGCGGTGTTCGAGCACGTGGCGCCGCAGGCCGACACGACGCGCGCGAGCAAGCTCGCCGAGGTGCG
CCGCGCGATGCAAGCGCAGGGCGCGCAGTGGCATTTCGTGTCGACGCTCGACGATCTCGCATGGCTGTTCAACCTGCGCG
GCGCCGACGTCAACTTCAATCCGGTGTTCGTTGCGCACGCAATGATCGGCGCCGAGCGCGCGACGCTGTTCGTCGCCGAC
GGCAAGGTGCCGCCTGCGCTGGCCGCGTCGCTCGCACAGGATGGCGTCGACGTCCGCGCCTACGACGCCGCGCGCGCGTC
GCTCGCGGCGCTGCCCGACGGCGCGACGCTGCTGATCGACCCGCGCCGCGTGACGTTCGGCACGCTCGAGGCCGTGCCGG
CCGGCGTGAAGCTCGTCGAGGCCGTGAATCCGTCGACGTTCGCGAAGTCGCGCAAGACGTCCGCCGAGATCGAGCACGTG
CGCGTGACGATGGAGCACGACGGCGCCGCGCTCGCGGAATTCTTCGCGTGGTTCGAACAGGCGGTGAACCGCGAGACGAT
CACCGAGCTGACGATCGAGGAAAAGCTCACGGCCGCGCGCGCCCGACGCCCCGGCTATGTGTCGGCGAGCTTCGCGACGA
TCGCCGGCTTCAACGCGAACGGCGCGATGCCGCACTACCACGCGACGCGCGAGTCGCACGCGACGATCGCCGGCGATGGC
CTGCTGCTGATCGATTCGGGCGGCCAGTACATGACGGGCACGACCGACATCACGCGCGTCGTGCCGGTCGGCACCGTCAG
CGACCTGCAGCGGCGCGATTTCACGATCGTGCTGAAGTCGATGATGGCGCTGTCGCGTGCCCGCTTCCCGCGCGGCATCC
GCTCGCCGATGCTCGACGCGATCGCGCGTGCGCCGATGTGGGCGGCCGGGCTCGACTACGGCCACGGCACCGGGCATGGC
GTCGGTTACTTCCTGAACGTGCATGAGGGCCCGCAGGTCATTTCGCACTACGCGCCGGCCGAGCCGTACACGGCGATGGA
AGAGGGGATGATCACGTCGATCGAGCCGGGCGTGTACCGTCCGGGCCAGTGGGGCATCCGGATCGAGAACCTGGTCGTGA
ACCGTGCGGCCGGAAAGACGGAATTCGGCGACTTCCTCGCCTTCGAGACGCTGACGCTGTGCCCGATCGACACGCGCTGC
GTGCTGATCGAGATGCTGCACGACGAAGAGCGCGCGTGGCTGAACACGTATCACGCGACGGTGCGCGAGCGCGTCGGCCG
GCATGTGAGCGGCGACGCGAAGGCGTGGCTCGACGCGCGTACGCAGCCGATCTGA

Upstream 100 bases:

>100_bases
CGAGACGCTCGAATGGCCGGTCTGCACCGGCGTCGCGTTCCTCGCCGTAGCCGTGACGGTCGCGCTGTCGGCCCGTCGCT
GAATGCTCTCAGGTGAAATC

Downstream 100 bases:

>100_bases
CGCAACGCACGGTAACGGCCGGATAGCGATCCGGTAACGATCGAACGACGGCCGGCCGATAACAGCGAGGGCAAGCAATG
GCAGACACCGCGGTGATCGT

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MNARLPEVSPVPARLALLRDAMVRENLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QADAELAGTGVQLMKMTGGQQSAPHVDWLAQNVAAGATVGVDGAVLGVAAARGLTAALSARGIALRTDVDLLDAIWPERP
GLPGDAVFEHVAPQADTTRASKLAEVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHAMIGAERATLFVAD
GKVPPALAASLAQDGVDVRAYDAARASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLVEAVNPSTFAKSRKTSAEIEHV
RVTMEHDGAALAEFFAWFEQAVNRETITELTIEEKLTAARARRPGYVSASFATIAGFNANGAMPHYHATRESHATIAGDG
LLLIDSGGQYMTGTTDITRVVPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGIRIENLVVNRAAGKTEFGDFLAFETLTLCPIDTRC
VLIEMLHDEERAWLNTYHATVRERVGRHVSGDAKAWLDARTQPI

Sequences:

>Translated_604_residues
MNARLPEVSPVPARLALLRDAMVRENLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QADAELAGTGVQLMKMTGGQQSAPHVDWLAQNVAAGATVGVDGAVLGVAAARGLTAALSARGIALRTDVDLLDAIWPERP
GLPGDAVFEHVAPQADTTRASKLAEVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHAMIGAERATLFVAD
GKVPPALAASLAQDGVDVRAYDAARASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLVEAVNPSTFAKSRKTSAEIEHV
RVTMEHDGAALAEFFAWFEQAVNRETITELTIEEKLTAARARRPGYVSASFATIAGFNANGAMPHYHATRESHATIAGDG
LLLIDSGGQYMTGTTDITRVVPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGIRIENLVVNRAAGKTEFGDFLAFETLTLCPIDTRC
VLIEMLHDEERAWLNTYHATVRERVGRHVSGDAKAWLDARTQPI
>Mature_604_residues
MNARLPEVSPVPARLALLRDAMVRENLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QADAELAGTGVQLMKMTGGQQSAPHVDWLAQNVAAGATVGVDGAVLGVAAARGLTAALSARGIALRTDVDLLDAIWPERP
GLPGDAVFEHVAPQADTTRASKLAEVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHAMIGAERATLFVAD
GKVPPALAASLAQDGVDVRAYDAARASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLVEAVNPSTFAKSRKTSAEIEHV
RVTMEHDGAALAEFFAWFEQAVNRETITELTIEEKLTAARARRPGYVSASFATIAGFNANGAMPHYHATRESHATIAGDG
LLLIDSGGQYMTGTTDITRVVPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGIRIENLVVNRAAGKTEFGDFLAFETLTLCPIDTRC
VLIEMLHDEERAWLNTYHATVRERVGRHVSGDAKAWLDARTQPI

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=612, Percent_Identity=36.9281045751634, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI264681565, Length=612, Percent_Identity=35.2941176470588, Blast_Score=345, Evalue=8e-95,
Organism=Homo sapiens, GI93141226, Length=604, Percent_Identity=33.4437086092715, Blast_Score=337, Evalue=1e-92,
Organism=Escherichia coli, GI1788728, Length=179, Percent_Identity=35.7541899441341, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=591, Percent_Identity=32.994923857868, Blast_Score=304, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI25149105, Length=605, Percent_Identity=27.2727272727273, Blast_Score=224, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322999, Length=654, Percent_Identity=31.039755351682, Blast_Score=283, Evalue=5e-77,
Organism=Drosophila melanogaster, GI17137632, Length=620, Percent_Identity=33.8709677419355, Blast_Score=321, Evalue=1e-87,
Organism=Drosophila melanogaster, GI161078230, Length=616, Percent_Identity=28.0844155844156, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI21357287, Length=616, Percent_Identity=28.0844155844156, Blast_Score=239, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 65228; Mature: 65228

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARLPEVSPVPARLALLRDAMVRENLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTLVVTADFAGLWVDSRYWVQADAELAGTGVQLMKMTGGQQSAPHVDWLAQNVAAGATVG
EEEEEEECCCEEEECCEEEEEECCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEC
VDGAVLGVAAARGLTAALSARGIALRTDVDLLDAIWPERPGLPGDAVFEHVAPQADTTRA
CCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHH
SKLAEVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHAMIGAERATLFVAD
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCEEEEEEC
GKVPPALAASLAQDGVDVRAYDAARASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLVE
CCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCEEEECCCEEEECHHHHCCCCCEEEE
AVNPSTFAKSRKTSAEIEHVRVTMEHDGAALAEFFAWFEQAVNRETITELTIEEKLTAAR
CCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ARRPGYVSASFATIAGFNANGAMPHYHATRESHATIAGDGLLLIDSGGQYMTGTTDITRV
HCCCCCEEECCCEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCEEECCCCCEEE
VPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCC
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGIRIENLVVNRAAGKT
EEEEEEECCCHHHHHHCCCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCC
EFGDFLAFETLTLCPIDTRCVLIEMLHDEERAWLNTYHATVRERVGRHVSGDAKAWLDAR
CHHHHHHHHEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC
>Mature Secondary Structure
MNARLPEVSPVPARLALLRDAMVRENLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTLVVTADFAGLWVDSRYWVQADAELAGTGVQLMKMTGGQQSAPHVDWLAQNVAAGATVG
EEEEEEECCCEEEECCEEEEEECCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEC
VDGAVLGVAAARGLTAALSARGIALRTDVDLLDAIWPERPGLPGDAVFEHVAPQADTTRA
CCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHH
SKLAEVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHAMIGAERATLFVAD
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCEEEEEEC
GKVPPALAASLAQDGVDVRAYDAARASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLVE
CCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCEEEECCCEEEECHHHHCCCCCEEEE
AVNPSTFAKSRKTSAEIEHVRVTMEHDGAALAEFFAWFEQAVNRETITELTIEEKLTAAR
CCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ARRPGYVSASFATIAGFNANGAMPHYHATRESHATIAGDGLLLIDSGGQYMTGTTDITRV
HCCCCCEEECCCEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCEEECCCCCEEE
VPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCC
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGIRIENLVVNRAAGKT
EEEEEEECCCHHHHHHCCCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCC
EFGDFLAFETLTLCPIDTRCVLIEMLHDEERAWLNTYHATVRERVGRHVSGDAKAWLDAR
CHHHHHHHHEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]