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The map label for this gene is mas [H]

Identifier: 116688514

GI number: 116688514

Start: 548496

End: 549473

Strand: Reverse

Name: mas [H]

Synonym: Bcen2424_0490

Alternate gene names: 116688514

Gene position: 549473-548496 (Counterclockwise)

Preceding gene: 116688516

Following gene: 116688513

Centisome position: 15.77

GC content: 72.29

Gene sequence:

>978_bases
ATGCGCAGCATCCGCTTCGACACCCCCGCCGCCGACATCGAGTCGCTCGACGCGCGCGTGCGGGACATCGCCCCGCCCGT
ACCGGCCGACGGCCAGATGCTGATCGAGGTGCGCGCGGCCGGCGTGAACCCGAGCGACGTGAAGGCCGCGCTCGGCCGCA
TGCCGCATGCGGTGTGGCCGCGCACGCCGGGGCGCGACTGGGCCGGCATCGTGCGCAGCGGCCCCGACAACTGGATCGGC
GCGCCGGTGTGGGGCTCGGGCGGCGATCTCGGCGTCGGGCGCGACGGTTCGCATGCGGAATGGCTCGTGCTGGACGCCGC
GCACGTGCGCCGCAAGCCGGGCGTGCTGACGCTCGAAGAGGCGGCCGGCGTGGGCGTGCCGTTCGTCACCGCATACGAGG
GCCTGCGCCGGGCCGGCATGCCGACGGCCGACGACGTCGTGCTCGTGTTCGGCGCGAACGGCAAGGTCGGCCAGGCCGCG
ATCCAGCTCGCCACCGCGCGCGGCGCGACCGTGATCGGCGTCGAGCGCGGGCCCGGCGACTATCGCGGCCATGCGTCAGG
CGACGTTTCCATGATCGACGCATCGAGCCGGACGGTGGCCGACGCGGTACGCGAATTGACCGGCGGCCACGGCGCGGACA
TCGTCTACAACACGGTCGGCAGCCCGTATTTCGAAGCGGCGAACGCGTCGATGGCGATCGGCGCGCGGCAGATCTTCATC
TCGACGATCGAGCGCAGCGTGCCGTTCGACATCTTCGCGTTCTATCGCGGCCAGCACACGTTCGTGGGCATCGATTCGCT
GCAGCTCGGCCCGGCCGCGGTCGCGCAGATCCTCGATACGCTCGCGCCCGGCTTCGGCAACGGGACGCTGCGCCCGTTCC
CGATCGGCGACGACTACGTGTACCCGCTCGAGCATGCGCACGACGCGTATCGCGCGGTGCTGGCCGGTGCGCGCGAGCGC
GTCATCCTCAAGCCCTGA

Upstream 100 bases:

>100_bases
CCGCGTCAAACCGGGCCCACTAGACTGCATTCACCGGTTTCATCCGCCGCACGCGCCGGCCCGCCGGGCCGGGCGGCCGC
CATCGTTCATGGAGATCATC

Downstream 100 bases:

>100_bases
CACCGGACCTTACGGGAGACCGCCATGATGGATTACGTGACCTCGCTCGCGGTGGGCGTCGGTGTCGGTGTGTTGTACGC
GCTGCTGCACGTGCGCTCGC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRSIRFDTPAADIESLDARVRDIAPPVPADGQMLIEVRAAGVNPSDVKAALGRMPHAVWPRTPGRDWAGIVRSGPDNWIG
APVWGSGGDLGVGRDGSHAEWLVLDAAHVRRKPGVLTLEEAAGVGVPFVTAYEGLRRAGMPTADDVVLVFGANGKVGQAA
IQLATARGATVIGVERGPGDYRGHASGDVSMIDASSRTVADAVRELTGGHGADIVYNTVGSPYFEAANASMAIGARQIFI
STIERSVPFDIFAFYRGQHTFVGIDSLQLGPAAVAQILDTLAPGFGNGTLRPFPIGDDYVYPLEHAHDAYRAVLAGARER
VILKP

Sequences:

>Translated_325_residues
MRSIRFDTPAADIESLDARVRDIAPPVPADGQMLIEVRAAGVNPSDVKAALGRMPHAVWPRTPGRDWAGIVRSGPDNWIG
APVWGSGGDLGVGRDGSHAEWLVLDAAHVRRKPGVLTLEEAAGVGVPFVTAYEGLRRAGMPTADDVVLVFGANGKVGQAA
IQLATARGATVIGVERGPGDYRGHASGDVSMIDASSRTVADAVRELTGGHGADIVYNTVGSPYFEAANASMAIGARQIFI
STIERSVPFDIFAFYRGQHTFVGIDSLQLGPAAVAQILDTLAPGFGNGTLRPFPIGDDYVYPLEHAHDAYRAVLAGARER
VILKP
>Mature_325_residues
MRSIRFDTPAADIESLDARVRDIAPPVPADGQMLIEVRAAGVNPSDVKAALGRMPHAVWPRTPGRDWAGIVRSGPDNWIG
APVWGSGGDLGVGRDGSHAEWLVLDAAHVRRKPGVLTLEEAAGVGVPFVTAYEGLRRAGMPTADDVVLVFGANGKVGQAA
IQLATARGATVIGVERGPGDYRGHASGDVSMIDASSRTVADAVRELTGGHGADIVYNTVGSPYFEAANASMAIGARQIFI
STIERSVPFDIFAFYRGQHTFVGIDSLQLGPAAVAQILDTLAPGFGNGTLRPFPIGDDYVYPLEHAHDAYRAVLAGARER
VILKP

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=338, Percent_Identity=28.698224852071, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI13236495, Length=338, Percent_Identity=28.698224852071, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI194239676, Length=331, Percent_Identity=28.7009063444109, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI22538446, Length=327, Percent_Identity=24.1590214067278, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI22538444, Length=327, Percent_Identity=24.1590214067278, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=177, Percent_Identity=33.8983050847458, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34220; Mature: 34220

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIRFDTPAADIESLDARVRDIAPPVPADGQMLIEVRAAGVNPSDVKAALGRMPHAVWP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCC
RTPGRDWAGIVRSGPDNWIGAPVWGSGGDLGVGRDGSHAEWLVLDAAHVRRKPGVLTLEE
CCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEEEHH
AAGVGVPFVTAYEGLRRAGMPTADDVVLVFGANGKVGQAAIQLATARGATVIGVERGPGD
HCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHEEEEECCCCEEEEEECCCCC
YRGHASGDVSMIDASSRTVADAVRELTGGHGADIVYNTVGSPYFEAANASMAIGARQIFI
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCCEEEHHHHHHHH
STIERSVPFDIFAFYRGQHTFVGIDSLQLGPAAVAQILDTLAPGFGNGTLRPFPIGDDYV
HHHHHCCCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
YPLEHAHDAYRAVLAGARERVILKP
CCHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MRSIRFDTPAADIESLDARVRDIAPPVPADGQMLIEVRAAGVNPSDVKAALGRMPHAVWP
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCC
RTPGRDWAGIVRSGPDNWIGAPVWGSGGDLGVGRDGSHAEWLVLDAAHVRRKPGVLTLEE
CCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEEEHH
AAGVGVPFVTAYEGLRRAGMPTADDVVLVFGANGKVGQAAIQLATARGATVIGVERGPGD
HCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHEEEEECCCCEEEEEECCCCC
YRGHASGDVSMIDASSRTVADAVRELTGGHGADIVYNTVGSPYFEAANASMAIGARQIFI
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCCEEEHHHHHHHH
STIERSVPFDIFAFYRGQHTFVGIDSLQLGPAAVAQILDTLAPGFGNGTLRPFPIGDDYV
HHHHHCCCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
YPLEHAHDAYRAVLAGARERVILKP
CCHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]