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The map label for this gene is flhA [H]

Identifier: 116688292

GI number: 116688292

Start: 308248

End: 310350

Strand: Direct

Name: flhA [H]

Synonym: Bcen2424_0268

Alternate gene names: 116688292

Gene position: 308248-310350 (Clockwise)

Preceding gene: 116688291

Following gene: 116688293

Centisome position: 8.85

GC content: 67.86

Gene sequence:

>2103_bases
ATGAGCACCCCGACCACCGGCCTGTTCGCGAAGCGCCCGAACGTGCTGGCAGGCACGAACCTGCGCGCGCTCGCGGGCCC
GATCCTCATCTGCATGATCCTGGGGATGATGATCCTGCCGCTGCCGCCGATGCTGCTGGATCTGCTGTTCACCTTCAACA
TCGCGCTGTCGGTGATGGTGCTGCTCGTCAGCATGTACACGATGAAGCCGCTCGACTTCGCGGCGTTCCCGAGCGTGCTG
CTGTTCTCGACGCTCCTGCGCCTGTCGCTGAACGTCGCGTCGACGCGCGTCGTGCTGCTCGAAGGCCACACCGGCCCCGA
CGCGGCCGGCCAGGTGATCGAGGCGTTCGGCCACTTCCTCGTGGGCGGCAACTTCGCGGTCGGCATCGTCGTGTTCGTGA
TCCTGATGATCATCAACTTCATGGTGATCACGAAGGGCGCGGGGCGGATCGCCGAAGTGTCCGCGCGCTTCACGCTCGAC
GCGATGCCCGGCAAGCAGATGGCGATCGACGCGGATCTCAACGCCGGCCTCATCAACGAGGAGCAGGCCCGCAAGCGCCG
CCTCGCCGTGTCGCAGGAAGCCGAGTTCTACGGGTCGATGGACGGCGCATCGAAGTTCGTGCGCGGCGACGCGATCGCCG
GCCTGATCATCATGGCGATCAACGTGATCGGCGGGCTGATCGTCGGGATGGTGCAGCACGACATGAGCTTCGCCGCGGCC
GGCACCAACTACACGCTGCTGACGATCGGCGACGGCCTCGTCGCGCAGATCCCGTCGCTCGTGATCTCGACCGCGGCCGG
CGTGATCGTGTCGCGCGTCGCGACCGACGAGGACATCGGCACGCAAATCACCGGCCAGCTGTTCACGAACCCGCGCGTGC
TGAACATCACCGGCGCGATCATCGTGCTGATGGGGCTGATCCCGGGGATGCCGCACTTCGCGTTCCTCGCGCTCGGCGGC
GGCGCGATCTGGCTGGCGCGCACCCAGACCAAGCGTGCGGCGGCGCGCAAGGCGGCCGGCGACGTGACCGACATCGCACC
GCCCGCGGTGCTGCCGGCCGACAGCCACGAAGCGACCTGGGACGACGTGCAGCTGATCGACCCGCTCGGCCTCGAAGTCG
GCTACCGGCTGATCCCGCTGGTCGACAAGAACAGCGACGGCGAGCTGCTCAAGCGCATCAAGAGCATCCGCAAGAAATTC
GCGCAGGAAATCGGCTTCCTGCCGCCGGTGATCCATATCCGCGACAACCTCGAACTGCGGCCGAACGCGTACCGGATCGC
GCTGAAGGGCGTCGAGATCGGCGCGGGCGAAGTGTTCCCGGGCCAGTGGCTCGCGATCAACCCGGGCCAGGTGACGGCCG
CGCTGCCGGGCGCCGTCACGCAGGACCCCGCGTTCGGGCTGCCGGCCGTGTGGATCGACGTCGCGCTGCGCGAGCAGGCG
CAGGTGTACGGCTACACGGTGGTCGACGCGAGCACGGTGGTCGCGACGCATCTGAACCATCTCGTCGTCCAGCACGCGGC
CGAGCTGCTCGGCCGCCAGGAAGTGCAGGCGCTCGTCGAGCGCACCGGCAAGGACGCGCCGTCGCTCGTCGAGGACCTCG
TGCCGAAGACGATCTCGCTCACCACGCTGCAGAAAGTGCTGCAGAACCTGCTCGAGGAAGGCGTGCCGATCCGCGACATG
CGTACGATCCTCGAGGCCGTGTCCGAGCATGCGGGCCGCGGCGACGCGTTCGAGATCACGGCCGCGGTGCGGCTCTCGCT
CGGCCGCGCGATCACGCAGCAGTGGTATCCGGGCAACGGCGAAATGCAGGTGATGGGCCTCGACGCGAATCTGGAGCGCG
TGCTGTCGCAGGCGCTCGCCACCGGCGCGAACCCGGGCCTCGAGCCCGGCCTTGCGCACAACCTTCTGACCGGCACGCAG
CAAGCGATGCTGCGTCAACAGAATCTCGGGCTGCCGCCGGTGCTGCTGGTGCAGCACGCGCTGCGCGCGATGCTCGCGCG
CTTCCTGCGCCGCAGCCTGCCGCAATTGAAAGTGCTGTCGTATGCCGAAGTGCCGGACACACGCACGATCAAAGTCGTTA
ACGTCATCGGGGGTTCCGCTTGA

Upstream 100 bases:

>100_bases
ATCTCGACGTGCCGGCCGAACTCGACAAGGGCACGTCGGTCGCCGCCGACGACGAGCGTGAAGAAGCCGAGGACACCCTC
GGCAAGCAAGGGAACGCAGC

Downstream 100 bases:

>100_bases
ACATTCGCAAATTCACCGGCGCAACGAGCCGCGACGCACTTCGTCTCGTGCGCGAGGCGCTCGGCGCCGACGCGGTCGTG
CTGTCGAACCGCACGCTCGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MSTPTTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVL
LFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLD
AMPGKQMAIDADLNAGLINEEQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAA
GTNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAIIVLMGLIPGMPHFAFLALGG
GAIWLARTQTKRAAARKAAGDVTDIAPPAVLPADSHEATWDDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKF
AQEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGAGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVALREQA
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLEEGVPIRDM
RTILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGNGEMQVMGLDANLERVLSQALATGANPGLEPGLAHNLLTGTQ
QAMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA

Sequences:

>Translated_700_residues
MSTPTTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVL
LFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLD
AMPGKQMAIDADLNAGLINEEQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAA
GTNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAIIVLMGLIPGMPHFAFLALGG
GAIWLARTQTKRAAARKAAGDVTDIAPPAVLPADSHEATWDDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKF
AQEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGAGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVALREQA
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLEEGVPIRDM
RTILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGNGEMQVMGLDANLERVLSQALATGANPGLEPGLAHNLLTGTQ
QAMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
>Mature_699_residues
STPTTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLL
FSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDA
MPGKQMAIDADLNAGLINEEQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAAG
TNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAIIVLMGLIPGMPHFAFLALGGG
AIWLARTQTKRAAARKAAGDVTDIAPPAVLPADSHEATWDDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFA
QEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGAGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVALREQAQ
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTISLTTLQKVLQNLLEEGVPIRDMR
TILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGNGEMQVMGLDANLERVLSQALATGANPGLEPGLAHNLLTGTQQ
AMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=696, Percent_Identity=65.3735632183908, Blast_Score=887, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74722; Mature: 74591

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMV
CCCCCCCCEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
VGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCH
EQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GTNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHEECCCEEEEHHHHH
IVLMGLIPGMPHFAFLALGGGAIWLARTQTKRAAARKAAGDVTDIAPPAVLPADSHEATW
HHHHHHHCCCCHHHHHEECCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELR
CCHHEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEC
PNAYRIALKGVEIGAGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVALREQA
CCEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTISL
HHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHH
TTLQKVLQNLLEEGVPIRDMRTILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGNG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCC
EMQVMGLDANLERVLSQALATGANPGLEPGLAHNLLTGTQQAMLRQQNLGLPPVLLVQHA
CEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
HHHHHHHHHHHCCCCEEHHEECCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
STPTTGLFAKRPNVLAGTNLRALAGPILICMILGMMILPLPPMLLDLLFTFNIALSVMV
CCCCCCCEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
VGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCH
EQARKRRLAVSQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMVQHDMSFAAA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GTNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLNITGAI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHEECCCEEEEHHHHH
IVLMGLIPGMPHFAFLALGGGAIWLARTQTKRAAARKAAGDVTDIAPPAVLPADSHEATW
HHHHHHHCCCCHHHHHEECCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DDVQLIDPLGLEVGYRLIPLVDKNSDGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELR
CCHHEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEC
PNAYRIALKGVEIGAGEVFPGQWLAINPGQVTAALPGAVTQDPAFGLPAVWIDVALREQA
CCEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTISL
HHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHH
TTLQKVLQNLLEEGVPIRDMRTILEAVSEHAGRGDAFEITAAVRLSLGRAITQQWYPGNG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCC
EMQVMGLDANLERVLSQALATGANPGLEPGLAHNLLTGTQQAMLRQQNLGLPPVLLVQHA
CEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
HHHHHHHHHHHCCCCEEHHEECCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]