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The map label for this gene is cheA [H]

Identifier: 116688280

GI number: 116688280

Start: 295079

End: 297349

Strand: Direct

Name: cheA [H]

Synonym: Bcen2424_0256

Alternate gene names: 116688280

Gene position: 295079-297349 (Clockwise)

Preceding gene: 116688279

Following gene: 116688281

Centisome position: 8.47

GC content: 69.79

Gene sequence:

>2271_bases
ATGACTCTCGACATCACTCAGTTCTACCAGACCTTTTTCGACGAAGCCGACGAGCTGCTCGCGCAGATGGAGCAGCTGCT
GCTGAACCTCGACGTCGATGCGCCCGATCCCGAGGATCTGGCGGCGATCTTCCGCGCCGCGCATTCGATCAAGGGCGGCG
CGGCGACGTTCGGCTTTTCCGCGCTGACCGATACGACGCACATCCTCGAATCGCTGCTCGACCGCGCGCGCAACCATGAG
CTGACGCTGACCAAGGAAATGATCGACGCGTTCCTGGAAACCAAGGACGTGTTGTCCGACCAGCTCGTCGACTACCGCGC
GAGTGCCGAACCGGACGCGGCCGCCGCCGCGACGATCTGCGCGAAGCTCGAACGGCTGAAGGCCGAAAGCGGCGCGGGCG
CGCCTGCTGCGGCCGCCGAGCCTGCGCCGGCCGCGCCGGTTGCACCGGTCGCTGCCGTGGCACCCGCCGTCGTCGAACCC
GCCGCTGCCGGCGATCGCGCCCCCGACCATGTGGTCGAACAGGCCGTCGCGGCCGCGCATCCGGCGGCCGACGCCGATGC
CGGCGGCCCGCACCTGAAGATCACGCTCGTGGGCGTCGACGCGAAGGATCGCGAACTGCTCACCGAGGAACTCGGCAATC
TCGGCCGGATCGTCGGCCGCGAGGAAACGGGCGCCGACCTGTCGCTGTGGGTCGAATCGGACGTGCCGTCGGACGACATC
GTCGCGGTGTGCTGCTTCGTGATCGACGAAAGCCAGATCCGCGTCGCGCACGGCACGGCGCCGGCCGCGCAGGCGGCGCC
GGCCGCCGCGCAGGGCGCCGCCGCCGAGGCTGCCGAACCGGCCGCCGTCGCGCAGCCGGCACGCGTCGAGGTGTTCGCGC
CGCCGCCGGCCGCGCCGCAACCGGCTGCTCCGGCGCCGGCGCCGGCCGAGCCGGCCGCCGCCGCCGCCCAGCAGCCGCAG
CCGCAACCACACGCACAACCCCAGCCGGCCGAACACGCGACGCCGGCCGCGGCCGCGCATCACGACGACAAGCGCGCACG
CCCGGCCGCCGCGGCCGCCGCCGGCGCCGAAGGCAGTTCGATCCGCGTCGGCGTCGAGAAGGTCGACCAGCTGATCAACC
TCGTCGGCGAACTGGTGATCACGCAGGCGATGCTGGCCGAGACGGCGACCGCATTCGATCCGGCGCTGCACGACCGCTTG
TTCAACGGGATGGCGCAGCTCGAGCGCAACGCGCGCGACCTGCAGGAAGCGGTGATGTCGATCCGCATGATGCCGATGGA
TTACGTGTTCAGCCGCTTCCCGCGGCTCGTGCGCGACCTCGCCGGCAAGCTCGGCAAACAGGTCGAACTGGTCACGTTCG
GCCAGGCGACCGAGCTCGACAAGAGCCTGATCGAACGGATCATCGATCCGCTCACGCACCTGGTGCGCAACAGCCTCGAC
CACGGCATCGAGACCGTCGACAAGCGCGTCGCCGCCGGCAAGGACGCGGTCGGCCAGCTCGTGCTGTCGGCCGCGCATCA
CGGCGGCAACATCGTGATCGAGGTGAGCGACGACGGCGCGGGCCTGAACCGCGAGCGCATCCTCGCGAAGGCCGCGAAGC
AGGGCATGCAGATCTCCGAGAACATCAGCGACGACGAAGTCTGGCAACTGATCTTCGCGCCGGGCTTCTCGACCGCCGAG
ACGGTGACCGACGTGTCGGGCCGCGGCGTCGGGATGGACGTCGTGAAGCGCAACATCCAGTCGATGGGCGGTCATGTCGA
AATCTCGTCGCAGGCCGGCCGCGGCACGACCACGCGGATCGTGCTGCCGCTCACGCTGGCGATCCTCGACGGGATGTCGG
TCAAGGTGGGCAGCGAGATCTTCATCCTGCCGCTGAACTTCGTGATGGAGTCGCTGCAGCCGTCGAACGACGACATCTAC
ACGGTCGGCAACGGCGAGCGCGTGGTGCGCGTGCGCGGCGAATACCTGCCGCTGGTCGCGCTGCACGAGGTGTTCTCGGT
CGAGGACGCGCGCACCGACCCGACGCAGGGGATCGTCACGATCATGGAAACCGAGGGGCGCCGCTTCGCGATGCTGATCG
ACGAGCTGGTCGGCCAGCAGCAGGTGGTCGTGAAGAACCTCGAAACCAACTACCGCAAGGTGCATGGCATCTCGGCGGCG
ACCATCCTCGGCGACGGCAGCGTCGCGCTGATCGTCGACGTCGCGGCGCTGAACCGCGAAACCCGTGCGACGCACGGCGC
CCGAGCCGGCGCCGAGCTCGCCGTCTTCTGA

Upstream 100 bases:

>100_bases
AAAGCCGATCGACCCGGGCGTGCTCGTCGAGCTGGTCGCGACGCTGTCCGAGCCGGCTGCCTCCTGACATGAACGCGACG
AATTCAACCGGTGACCGGGC

Downstream 100 bases:

>100_bases
CTCTCGCCATTCAACCGATTGGGGGCAAACGTGTCTGCTGAAGTCCAAATGATCAATCCGGCCGCGGCGAATGCCGCGAC
GAGCCGCCGCGACGCGGCGC

Product: CheA signal transduction histidine kinases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVDAPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHE
LTLTKEMIDAFLETKDVLSDQLVDYRASAEPDAAAAATICAKLERLKAESGAGAPAAAAEPAPAAPVAPVAAVAPAVVEP
AAAGDRAPDHVVEQAVAAAHPAADADAGGPHLKITLVGVDAKDRELLTEELGNLGRIVGREETGADLSLWVESDVPSDDI
VAVCCFVIDESQIRVAHGTAPAAQAAPAAAQGAAAEAAEPAAVAQPARVEVFAPPPAAPQPAAPAPAPAEPAAAAAQQPQ
PQPHAQPQPAEHATPAAAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETATAFDPALHDRL
FNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLD
HGIETVDKRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWQLIFAPGFSTAE
TVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIY
TVGNGERVVRVRGEYLPLVALHEVFSVEDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAA
TILGDGSVALIVDVAALNRETRATHGARAGAELAVF

Sequences:

>Translated_756_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVDAPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHE
LTLTKEMIDAFLETKDVLSDQLVDYRASAEPDAAAAATICAKLERLKAESGAGAPAAAAEPAPAAPVAPVAAVAPAVVEP
AAAGDRAPDHVVEQAVAAAHPAADADAGGPHLKITLVGVDAKDRELLTEELGNLGRIVGREETGADLSLWVESDVPSDDI
VAVCCFVIDESQIRVAHGTAPAAQAAPAAAQGAAAEAAEPAAVAQPARVEVFAPPPAAPQPAAPAPAPAEPAAAAAQQPQ
PQPHAQPQPAEHATPAAAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETATAFDPALHDRL
FNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLD
HGIETVDKRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWQLIFAPGFSTAE
TVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIY
TVGNGERVVRVRGEYLPLVALHEVFSVEDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAA
TILGDGSVALIVDVAALNRETRATHGARAGAELAVF
>Mature_755_residues
TLDITQFYQTFFDEADELLAQMEQLLLNLDVDAPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHEL
TLTKEMIDAFLETKDVLSDQLVDYRASAEPDAAAAATICAKLERLKAESGAGAPAAAAEPAPAAPVAPVAAVAPAVVEPA
AAGDRAPDHVVEQAVAAAHPAADADAGGPHLKITLVGVDAKDRELLTEELGNLGRIVGREETGADLSLWVESDVPSDDIV
AVCCFVIDESQIRVAHGTAPAAQAAPAAAQGAAAEAAEPAAVAQPARVEVFAPPPAAPQPAAPAPAPAEPAAAAAQQPQP
QPHAQPQPAEHATPAAAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETATAFDPALHDRLF
NGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDH
GIETVDKRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWQLIFAPGFSTAET
VTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIYT
VGNGERVVRVRGEYLPLVALHEVFSVEDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAAT
ILGDGSVALIVDVAALNRETRATHGARAGAELAVF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=394, Percent_Identity=74.1116751269035, Blast_Score=595, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79538; Mature: 79406

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVDAPDPEDLAAIFRAAHSIKGGAATFGFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
ALTDTTHILESLLDRARNHELTLTKEMIDAFLETKDVLSDQLVDYRASAEPDAAAAATIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AKLERLKAESGAGAPAAAAEPAPAAPVAPVAAVAPAVVEPAAAGDRAPDHVVEQAVAAAH
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
PAADADAGGPHLKITLVGVDAKDRELLTEELGNLGRIVGREETGADLSLWVESDVPSDDI
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHH
VAVCCFVIDESQIRVAHGTAPAAQAAPAAAQGAAAEAAEPAAVAQPARVEVFAPPPAAPQ
HHHHHHHCCCCCEEEEECCCCCHHCCCCHHCCCCHHCCCCHHHCCCCEEEEECCCCCCCC
PAAPAPAPAEPAAAAAQQPQPQPHAQPQPAEHATPAAAAHHDDKRARPAAAAAAGAEGSS
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHHCCCCCCE
IRVGVEKVDQLINLVGELVITQAMLAETATAFDPALHDRLFNGMAQLERNARDLQEAVMS
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLD
HHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
HGIETVDKRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISE
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHHC
NISDDEVWQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRI
CCCHHHHEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEE
VLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEYLPLVA
HHHHHHHHHCCCCEEECCEEEEEEHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCHHH
LHEVFSVEDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAA
HHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEE
TILGDGSVALIVDVAALNRETRATHGARAGAELAVF
EEECCCCEEEEEEHHHHCCHHHHHCCCCCCCCEECC
>Mature Secondary Structure 
TLDITQFYQTFFDEADELLAQMEQLLLNLDVDAPDPEDLAAIFRAAHSIKGGAATFGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
ALTDTTHILESLLDRARNHELTLTKEMIDAFLETKDVLSDQLVDYRASAEPDAAAAATIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AKLERLKAESGAGAPAAAAEPAPAAPVAPVAAVAPAVVEPAAAGDRAPDHVVEQAVAAAH
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
PAADADAGGPHLKITLVGVDAKDRELLTEELGNLGRIVGREETGADLSLWVESDVPSDDI
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHH
VAVCCFVIDESQIRVAHGTAPAAQAAPAAAQGAAAEAAEPAAVAQPARVEVFAPPPAAPQ
HHHHHHHCCCCCEEEEECCCCCHHCCCCHHCCCCHHCCCCHHHCCCCEEEEECCCCCCCC
PAAPAPAPAEPAAAAAQQPQPQPHAQPQPAEHATPAAAAHHDDKRARPAAAAAAGAEGSS
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHHCCCCCCE
IRVGVEKVDQLINLVGELVITQAMLAETATAFDPALHDRLFNGMAQLERNARDLQEAVMS
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLD
HHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
HGIETVDKRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISE
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHHC
NISDDEVWQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRI
CCCHHHHEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEE
VLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEYLPLVA
HHHHHHHHHCCCCEEECCEEEEEEHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCHHH
LHEVFSVEDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAA
HHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEE
TILGDGSVALIVDVAALNRETRATHGARAGAELAVF
EEECCCCEEEEEEHHHHCCHHHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]