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The map label for this gene is cheW [H]

Identifier: 116688281

GI number: 116688281

Start: 297380

End: 297913

Strand: Direct

Name: cheW [H]

Synonym: Bcen2424_0257

Alternate gene names: 116688281

Gene position: 297380-297913 (Clockwise)

Preceding gene: 116688280

Following gene: 116688282

Centisome position: 8.54

GC content: 63.67

Gene sequence:

>534_bases
GTGTCTGCTGAAGTCCAAATGATCAATCCGGCCGCGGCGAATGCCGCGACGAGCCGCCGCGACGCGGCGCACGGCGATGC
GACGGGCCAGGAATTCCTCGTGTTCACGCTCGGCGACGAGGAATACGGGATCGACATCCTGAAAGTGCAGGAAATCCGCG
GCTACGACAGCGTCACGCGCATCGCGAACGCGCCCGAGTTCATCAAGGGCGTGATCAACCTGCGCGGGATCATCGTGCCG
ATCGTCGACATGCGGATCAAGTTCCACCTCGGCCGCGTCGAGTACGACCACCAGACCGTCGTGATCATCCTGAACGTGTC
GAACCGCGTGGTCGGGATGGTGGTCGACGGCGTGTCGGACGTGCTGACGCTGCAGACCGACCAGATCATGCCGGCGCCGG
AATTCGGCGCGACGCTGACGACCGAGTACCTGACGGGCCTCGGCACGGTCGACGGCCGGATGCTGATCCTGATGGACATC
GAGAAGCTGATGTCGAGCCGTGAAATGGCGCTGATCGAGACACTCGGCGGGTAA

Upstream 100 bases:

>100_bases
CGCGGCGCTGAACCGCGAAACCCGTGCGACGCACGGCGCCCGAGCCGGCGCCGAGCTCGCCGTCTTCTGACTCTCGCCAT
TCAACCGATTGGGGGCAAAC

Downstream 100 bases:

>100_bases
GCGCGCCGCGCGCGCAGCAATTTCGGGAGAATCTGCAATGTTGCATAACTGGTCGATCCGCACGACGCTCACGGCGGTCG
GACTCATCCTCGTGTGCCTG

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSAEVQMINPAAANAATSRRDAAHGDATGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIANAPEFIKGVINLRGIIVP
IVDMRIKFHLGRVEYDHQTVVIILNVSNRVVGMVVDGVSDVLTLQTDQIMPAPEFGATLTTEYLTGLGTVDGRMLILMDI
EKLMSSREMALIETLGG

Sequences:

>Translated_177_residues
MSAEVQMINPAAANAATSRRDAAHGDATGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIANAPEFIKGVINLRGIIVP
IVDMRIKFHLGRVEYDHQTVVIILNVSNRVVGMVVDGVSDVLTLQTDQIMPAPEFGATLTTEYLTGLGTVDGRMLILMDI
EKLMSSREMALIETLGG
>Mature_176_residues
SAEVQMINPAAANAATSRRDAAHGDATGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTRIANAPEFIKGVINLRGIIVPI
VDMRIKFHLGRVEYDHQTVVIILNVSNRVVGMVVDGVSDVLTLQTDQIMPAPEFGATLTTEYLTGLGTVDGRMLILMDIE
KLMSSREMALIETLGG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=149, Percent_Identity=71.8120805369127, Blast_Score=220, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19294; Mature: 19162

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEVQMINPAAANAATSRRDAAHGDATGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTR
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHH
IANAPEFIKGVINLRGIIVPIVDMRIKFHLGRVEYDHQTVVIILNVSNRVVGMVVDGVSD
HCCCHHHHHHHHHHCEEEEEEEEEEEEEEECEEEECCCEEEEEEECCCCEEEEEECCCHH
VLTLQTDQIMPAPEFGATLTTEYLTGLGTVDGRMLILMDIEKLMSSREMALIETLGG
EEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCEEEEEECCC
>Mature Secondary Structure 
SAEVQMINPAAANAATSRRDAAHGDATGQEFLVFTLGDEEYGIDILKVQEIRGYDSVTR
CCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHH
IANAPEFIKGVINLRGIIVPIVDMRIKFHLGRVEYDHQTVVIILNVSNRVVGMVVDGVSD
HCCCHHHHHHHHHHCEEEEEEEEEEEEEEECEEEECCCEEEEEEECCCCEEEEEECCCHH
VLTLQTDQIMPAPEFGATLTTEYLTGLGTVDGRMLILMDIEKLMSSREMALIETLGG
EEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]