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The map label for this gene is cof [C]

Identifier: 116688271

GI number: 116688271

Start: 287465

End: 288289

Strand: Direct

Name: cof [C]

Synonym: Bcen2424_0247

Alternate gene names: 116688271

Gene position: 287465-288289 (Clockwise)

Preceding gene: 116688270

Following gene: 116688273

Centisome position: 8.25

GC content: 66.18

Gene sequence:

>825_bases
ATGTACAAAGTCATCGCCACCGATCTCGACGGTACGCTGCTGAACAGCGACCACCAGCTCGACCCGTACACGATCGACAC
CGTTCGCCGGCTCGACCGCGACGGCGTGCAATTCGTGATCGCCACGGGGCGCCACTATGCGGACGTCGCCGGCATTCGCG
ACGTGCTCGGCATCCGGCCGTACCTGATCACGTCGAACGGCGCGCGCGTGCATGCGCCGGACGACACGAAGATTCACGCG
CAGGACATCGACGCAGCGATCGTGCGCAGCCTCGTGCAGCCGGCAGTCGTCGGCGCGCACGGCCGCGTGATCGTCAACCT
GTTCACCAACGACGGCTGGCTGATCGACCGCGACGCGCCGCACCTGCTCGAATTCCATCAGGATTCGGGCTTCCGGTACG
ACGTGATCGACATGGCCGCGCACGACGGCGCGGACATCGCGAAGGTGCTGTATATCGGCGAACCGGCCGATCTGGCGGTC
GTCGCCGAGCAGATGCGCGTGCAGTTCGGCGACGCGCTGTATGTCACGTACTCGCTGCCCGACTGCCTCGAAGTGATGAC
CGCGAACGTGTCGAAGGGGCGCGCGCTGCGCGCGGTGCTCGCGCGGCTCGGCGTCGATGCCGGCCACTGCATCGCATTCG
GCGACAACATGAACGACATCGATCTGCTCGAAACCGCCGGTCATGCGTTCATGATGAACAACGCGAACCCCGACCTGATC
GCGCGGCTGCCGCACGTCCCGCGGATCGGCAACAACTTCGACGCGGGCGTCGCCCGCCATCTGCGCACGCTGTTCTCGCT
GGAAGACGACGTCGTCGCGTCCTGA

Upstream 100 bases:

>100_bases
GCACTGCGGGCGGCAACCGCCCGGCAACCGCCCGGCGCGCTACCGGGCACGACGTTAAAATGACGCTTCCTCCGTGCCCC
GAGCGCCACTCTCCCGCCCC

Downstream 100 bases:

>100_bases
GCGTCCGCCCCGGGCGCGTGTCCCGCGCGGAAATGAAAAACGGGCGCCAGGGGCGCCCGTCGAAATTACCTGCCTCGATG
TTCTTCGACAGCGTGAGGCT

Product: Cof-like hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MYKVIATDLDGTLLNSDHQLDPYTIDTVRRLDRDGVQFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHAPDDTKIHA
QDIDAAIVRSLVQPAVVGAHGRVIVNLFTNDGWLIDRDAPHLLEFHQDSGFRYDVIDMAAHDGADIAKVLYIGEPADLAV
VAEQMRVQFGDALYVTYSLPDCLEVMTANVSKGRALRAVLARLGVDAGHCIAFGDNMNDIDLLETAGHAFMMNNANPDLI
ARLPHVPRIGNNFDAGVARHLRTLFSLEDDVVAS

Sequences:

>Translated_274_residues
MYKVIATDLDGTLLNSDHQLDPYTIDTVRRLDRDGVQFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHAPDDTKIHA
QDIDAAIVRSLVQPAVVGAHGRVIVNLFTNDGWLIDRDAPHLLEFHQDSGFRYDVIDMAAHDGADIAKVLYIGEPADLAV
VAEQMRVQFGDALYVTYSLPDCLEVMTANVSKGRALRAVLARLGVDAGHCIAFGDNMNDIDLLETAGHAFMMNNANPDLI
ARLPHVPRIGNNFDAGVARHLRTLFSLEDDVVAS
>Mature_274_residues
MYKVIATDLDGTLLNSDHQLDPYTIDTVRRLDRDGVQFVIATGRHYADVAGIRDVLGIRPYLITSNGARVHAPDDTKIHA
QDIDAAIVRSLVQPAVVGAHGRVIVNLFTNDGWLIDRDAPHLLEFHQDSGFRYDVIDMAAHDGADIAKVLYIGEPADLAV
VAEQMRVQFGDALYVTYSLPDCLEVMTANVSKGRALRAVLARLGVDAGHCIAFGDNMNDIDLLETAGHAFMMNNANPDLI
ARLPHVPRIGNNFDAGVARHLRTLFSLEDDVVAS

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI48994981, Length=266, Percent_Identity=40.2255639097744, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87081741, Length=261, Percent_Identity=35.2490421455939, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 29945; Mature: 29945

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKVIATDLDGTLLNSDHQLDPYTIDTVRRLDRDGVQFVIATGRHYADVAGIRDVLGIRP
CEEEEEECCCCEEECCCCCCCCEEHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCC
YLITSNGARVHAPDDTKIHAQDIDAAIVRSLVQPAVVGAHGRVIVNLFTNDGWLIDRDAP
EEEECCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCH
HLLEFHQDSGFRYDVIDMAAHDGADIAKVLYIGEPADLAVVAEQMRVQFGDALYVTYSLP
HHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCH
DCLEVMTANVSKGRALRAVLARLGVDAGHCIAFGDNMNDIDLLETAGHAFMMNNANPDLI
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCEEEECCCCCCCE
ARLPHVPRIGNNFDAGVARHLRTLFSLEDDVVAS
EECCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MYKVIATDLDGTLLNSDHQLDPYTIDTVRRLDRDGVQFVIATGRHYADVAGIRDVLGIRP
CEEEEEECCCCEEECCCCCCCCEEHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCC
YLITSNGARVHAPDDTKIHAQDIDAAIVRSLVQPAVVGAHGRVIVNLFTNDGWLIDRDAP
EEEECCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCH
HLLEFHQDSGFRYDVIDMAAHDGADIAKVLYIGEPADLAVVAEQMRVQFGDALYVTYSLP
HHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCH
DCLEVMTANVSKGRALRAVLARLGVDAGHCIAFGDNMNDIDLLETAGHAFMMNNANPDLI
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCEEEECCCCCCCE
ARLPHVPRIGNNFDAGVARHLRTLFSLEDDVVAS
EECCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]