| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
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The map label for this gene is gra-orf6 [H]
Identifier: 116688198
GI number: 116688198
Start: 192700
End: 193467
Strand: Direct
Name: gra-orf6 [H]
Synonym: Bcen2424_0174
Alternate gene names: 116688198
Gene position: 192700-193467 (Clockwise)
Preceding gene: 116688197
Following gene: 116688199
Centisome position: 5.53
GC content: 64.58
Gene sequence:
>768_bases ATGGCCCATCCGAATCCAGCAGCACTCGTAACCGGCTCCGCATCGGGCATTGGCCGCGCCATTGCAGTGGCGCTTGCGCG CGCCGGCTTCGACATCGGCGTTAACTACAGCCGCAGCGAGCGCGAGGCAAAAGAAACCGCGCGCCTCGTGAACGAAGCGG GCCGCGACGCCCTGATTATTCGAGCCGACGTCAGCGACGAAAGCCAGGTGGTGAGCATGCTGCGTCAGTTCGAGGAAGCG TTCGGCGGCCGCCTCGATCTGCTCGTCAACAACGCCGGCACCACGATCGACACGCCGCCTGCGCAGTTCGATACGGTCGA CGTGGCGGATTTCGATCGCGTGTTCAACGTCAACGTGCGCGGCTGCTTCCTTGTGACGAAACACGCCGCGCGCCTGCTGC GTCAGATGGACCGCGCCGACGTCATCAACACGGCAAGCATTGTCGGTCTGCGGCCGGGTCCTCAGCCTTTGCCCTACTCC GCCAGCAAGGCCGCGATTGTCTCGATGACGCAAACGCTCGCGGGTGCGCTCGGCCCGAAGATCCGCGTCAATGCGGTAGC GCCGGGATGGATGGAAGGCGACTGGATGGAGCGTGCGTTGGGCGACAACTATAACCGGCTGATGGAGAGGCGCGCCAAGG CAACGCCGCTCAAGCGTTGCGCGACGGCAGAGGACGTCGGCGAAACCGTGGTCGCACTTGCCACGACGATGCGCTTCGTC GACGGTCAGGTGATCGTCATCGACGGCGGCTACAGCTCGATCACCTGA
Upstream 100 bases:
>100_bases CAACAGCTTCTTAGGTACAAACGCCTACTTGCAGAGCACTTTGAAAACGCCTAAAAATGAGCATGATCATTTTTGAGTGG AATCGCAAAGGATGACAAAC
Downstream 100 bases:
>100_bases TCGACGCGCCCCCTGCCCCCACTCAAGGAGACACTGATGACCGCCTCATCCCATGCCTCTCGCGACGTGTTCGACGGCGT GACGCCGTTTCCCGCCGACT
Product: short-chain dehydrogenase/reductase SDR
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: ORF6 [H]
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MAHPNPAALVTGSASGIGRAIAVALARAGFDIGVNYSRSEREAKETARLVNEAGRDALIIRADVSDESQVVSMLRQFEEA FGGRLDLLVNNAGTTIDTPPAQFDTVDVADFDRVFNVNVRGCFLVTKHAARLLRQMDRADVINTASIVGLRPGPQPLPYS ASKAAIVSMTQTLAGALGPKIRVNAVAPGWMEGDWMERALGDNYNRLMERRAKATPLKRCATAEDVGETVVALATTMRFV DGQVIVIDGGYSSIT
Sequences:
>Translated_255_residues MAHPNPAALVTGSASGIGRAIAVALARAGFDIGVNYSRSEREAKETARLVNEAGRDALIIRADVSDESQVVSMLRQFEEA FGGRLDLLVNNAGTTIDTPPAQFDTVDVADFDRVFNVNVRGCFLVTKHAARLLRQMDRADVINTASIVGLRPGPQPLPYS ASKAAIVSMTQTLAGALGPKIRVNAVAPGWMEGDWMERALGDNYNRLMERRAKATPLKRCATAEDVGETVVALATTMRFV DGQVIVIDGGYSSIT >Mature_254_residues AHPNPAALVTGSASGIGRAIAVALARAGFDIGVNYSRSEREAKETARLVNEAGRDALIIRADVSDESQVVSMLRQFEEAF GGRLDLLVNNAGTTIDTPPAQFDTVDVADFDRVFNVNVRGCFLVTKHAARLLRQMDRADVINTASIVGLRPGPQPLPYSA SKAAIVSMTQTLAGALGPKIRVNAVAPGWMEGDWMERALGDNYNRLMERRAKATPLKRCATAEDVGETVVALATTMRFVD GQVIVIDGGYSSIT
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=33.739837398374, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=31.8897637795276, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=28.9795918367347, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=27.8625954198473, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=31.5175097276265, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=30.5418719211823, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=30.859375, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI40254986, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=33.8383838383838, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI209862901, Length=253, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI19923983, Length=253, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI210032110, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=31.0734463276836, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4504505, Length=186, Percent_Identity=28.494623655914, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=30.4, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=34.9206349206349, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=32.9365079365079, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=32.9317269076305, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=30.8, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=29.3172690763052, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=29.0196078431373, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=29.0983606557377, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=28.0487804878049, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.2945736434109, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=30, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1787526, Length=183, Percent_Identity=32.2404371584699, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=27.8884462151394, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1788891, Length=232, Percent_Identity=28.8793103448276, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=32.5581395348837, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17544670, Length=257, Percent_Identity=33.0739299610895, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=31.8007662835249, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=31.9066147859922, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=31.6205533596838, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=32.4528301886792, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=31.4176245210728, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.9160305343511, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.8973384030418, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=30.3501945525292, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.8449612403101, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=29.2592592592593, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=31.0606060606061, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.5454545454545, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=27.9245283018868, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=28.2527881040892, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=28.8, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=27.5590551181102, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538182, Length=195, Percent_Identity=34.3589743589744, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=28.3018867924528, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=31.1740890688259, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=29.8804780876494, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=27.8625954198473, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71997099, Length=241, Percent_Identity=24.4813278008299, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=28.6259541984733, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=26.6129032258064, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17555612, Length=257, Percent_Identity=25.6809338521401, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17568967, Length=176, Percent_Identity=28.4090909090909, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508651, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI71982365, Length=143, Percent_Identity=31.4685314685315, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=26.9076305220884, Blast_Score=73, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=229, Percent_Identity=27.0742358078603, Blast_Score=65, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=8e-12, Organism=Drosophila melanogaster, GI23397609, Length=264, Percent_Identity=34.8484848484849, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=34.8178137651822, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=32.3886639676113, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=34.1269841269841, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=30.952380952381, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=28.8617886178862, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24644337, Length=202, Percent_Identity=32.1782178217822, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=33.4630350194552, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=31.25, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI28571387, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007236, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 27288; Mature: 27157
Theoretical pI: Translated: 6.55; Mature: 6.55
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAHPNPAALVTGSASGIGRAIAVALARAGFDIGVNYSRSEREAKETARLVNEAGRDALII CCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE RADVSDESQVVSMLRQFEEAFGGRLDLLVNNAGTTIDTPPAQFDTVDVADFDRVFNVNVR EECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHEEECCCC GCFLVTKHAARLLRQMDRADVINTASIVGLRPGPQPLPYSASKAAIVSMTQTLAGALGPK EEEEHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCC IRVNAVAPGWMEGDWMERALGDNYNRLMERRAKATPLKRCATAEDVGETVVALATTMRFV EEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHH DGQVIVIDGGYSSIT CCEEEEEECCCCCCC >Mature Secondary Structure AHPNPAALVTGSASGIGRAIAVALARAGFDIGVNYSRSEREAKETARLVNEAGRDALII CCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE RADVSDESQVVSMLRQFEEAFGGRLDLLVNNAGTTIDTPPAQFDTVDVADFDRVFNVNVR EECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHEEECCCC GCFLVTKHAARLLRQMDRADVINTASIVGLRPGPQPLPYSASKAAIVSMTQTLAGALGPK EEEEHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCC IRVNAVAPGWMEGDWMERALGDNYNRLMERRAKATPLKRCATAEDVGETVVALATTMRFV EEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHH DGQVIVIDGGYSSIT CCEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2583128; 9831526 [H]