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The map label for this gene is tcp [H]

Identifier: 116688178

GI number: 116688178

Start: 171556

End: 172761

Strand: Reverse

Name: tcp [H]

Synonym: Bcen2424_0154

Alternate gene names: 116688178

Gene position: 172761-171556 (Counterclockwise)

Preceding gene: 116688179

Following gene: 116688177

Centisome position: 4.96

GC content: 65.09

Gene sequence:

>1206_bases
ATGGTCATGACAAATGTTCGCATTCCCGCCGCGCTGAGCATCATCGTCGGCGGCGGGCTTACTATGACGCTGGCGGTCGC
GGCGGCGGGCGCGGTCTGCGTCGATGCCGCTTTGACGCATGCAGAGGCGGCGTTGTGGTCCGCGCGAGGCGTGCGAGATG
TTGACGTGATCACCCCGCTCGCAGATTTGCGGCACTTGCGGCACATCGCACTGCCATGCCTCGCGGCATTCACGGCGGCC
AGCATATTGCTGGCATTCGCTGCCCGGCGCTGGCTCGATACGAAGGTCGTGCGTCCGCTCGACTGCGCGATGCGATCCGT
CAATGCCATCGCGCTCGGCGAATTGCACGAGACGATCGTGATCGACGAAAGCACTCAGGCGCGGCGGCTCTTTGCTGCCC
TTGCACAGATGCAGCGAGGACTCGTCGAGACGCTTTCGCTAGTCACCAGCGAAGCCGTTGCGATCGACGACTGCGCGTCG
CATCTGTCCAGCCAGAACCAGCGGCTCGCGAGCGGCACCGAATCACAGGCCGCCGCGATCGAGCAAACAGCGGCGACGAT
GCAACAGATCAGCGACGGCGTGCACCGCAGCGCACACGTGGCGGCCCAGACGAACCGGCTGGCCGACAACGCCGCGACAC
TCGCCGACGAAAGCCGCACCCGGGTACGGGCCGTGACCGACGCGATGGATTCGATCGCCAGGGACTCGCGGCAGATCAGC
GCGGTCGTTTCCGTGGTCAACGGGCTTGCGTTCCGGACGAACATCCTCGCGCTCAACGCGGCCGTCGAAGCGGCCCGCGC
CGGACATCAAGGCAAGGGATTCGCGGTGGTCGCCGCCGAAGTGCGCAGCCTCGCGCAACGAAGCGCGATCGCGGCCCGCG
AAATCGAGGACTTGATAGCCAATGCCCGCAGCGCGATCGAGAAAGGCGCGCGACTCTGCGAGGACGTCGGTACGGCGATG
GACAATGTCGTCGCGGCAGCCCATGAAGTCGTCGAACTCAGCGATGACATGAGCCGCTCCGCGAGCGAGCAAAGCCTTGG
CGTTCAGCAGTTGAACGAAGCAATCAAAGCGATCGACTCGGTAACCCAACAAAACGCGGCGATGGTCCAGCATTTCGTCG
AGACGACAGAGGATCTCAATGGACGCGCCCGCGCGCTCGCCGGTGCAGTGGGGGCATGGAAGCTGGGGCGAGACGCAGCG
AGTTAG

Upstream 100 bases:

>100_bases
GACGGACGCGGCGGGACCTGGCATTGCCGTCGCAGCGGGCAAAAACATCACGACCGAGATTCTCGGCATCGTGCATACCT
TCTAGTCAGCGAGTCCGACG

Downstream 100 bases:

>100_bases
CTGCGGCTCCTCGGGCCTCGCTCTGCTGCACGATTTACCGGGACCGCGCCGACGCTCCTTTTGTCGCGTAGTGTCAGGAC
TCCTGTCTACTTGGTGAACG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MVMTNVRIPAALSIIVGGGLTMTLAVAAAGAVCVDAALTHAEAALWSARGVRDVDVITPLADLRHLRHIALPCLAAFTAA
SILLAFAARRWLDTKVVRPLDCAMRSVNAIALGELHETIVIDESTQARRLFAALAQMQRGLVETLSLVTSEAVAIDDCAS
HLSSQNQRLASGTESQAAAIEQTAATMQQISDGVHRSAHVAAQTNRLADNAATLADESRTRVRAVTDAMDSIARDSRQIS
AVVSVVNGLAFRTNILALNAAVEAARAGHQGKGFAVVAAEVRSLAQRSAIAAREIEDLIANARSAIEKGARLCEDVGTAM
DNVVAAAHEVVELSDDMSRSASEQSLGVQQLNEAIKAIDSVTQQNAAMVQHFVETTEDLNGRARALAGAVGAWKLGRDAA
S

Sequences:

>Translated_401_residues
MVMTNVRIPAALSIIVGGGLTMTLAVAAAGAVCVDAALTHAEAALWSARGVRDVDVITPLADLRHLRHIALPCLAAFTAA
SILLAFAARRWLDTKVVRPLDCAMRSVNAIALGELHETIVIDESTQARRLFAALAQMQRGLVETLSLVTSEAVAIDDCAS
HLSSQNQRLASGTESQAAAIEQTAATMQQISDGVHRSAHVAAQTNRLADNAATLADESRTRVRAVTDAMDSIARDSRQIS
AVVSVVNGLAFRTNILALNAAVEAARAGHQGKGFAVVAAEVRSLAQRSAIAAREIEDLIANARSAIEKGARLCEDVGTAM
DNVVAAAHEVVELSDDMSRSASEQSLGVQQLNEAIKAIDSVTQQNAAMVQHFVETTEDLNGRARALAGAVGAWKLGRDAA
S
>Mature_401_residues
MVMTNVRIPAALSIIVGGGLTMTLAVAAAGAVCVDAALTHAEAALWSARGVRDVDVITPLADLRHLRHIALPCLAAFTAA
SILLAFAARRWLDTKVVRPLDCAMRSVNAIALGELHETIVIDESTQARRLFAALAQMQRGLVETLSLVTSEAVAIDDCAS
HLSSQNQRLASGTESQAAAIEQTAATMQQISDGVHRSAHVAAQTNRLADNAATLADESRTRVRAVTDAMDSIARDSRQIS
AVVSVVNGLAFRTNILALNAAVEAARAGHQGKGFAVVAAEVRSLAQRSAIAAREIEDLIANARSAIEKGARLCEDVGTAM
DNVVAAAHEVVELSDDMSRSASEQSLGVQQLNEAIKAIDSVTQQNAAMVQHFVETTEDLNGRARALAGAVGAWKLGRDAA
S

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=332, Percent_Identity=37.3493975903614, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788195, Length=310, Percent_Identity=40.6451612903226, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787690, Length=349, Percent_Identity=39.541547277937, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI2367378, Length=286, Percent_Identity=41.6083916083916, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789453, Length=352, Percent_Identity=34.375, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 42028; Mature: 42028

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMTNVRIPAALSIIVGGGLTMTLAVAAAGAVCVDAALTHAEAALWSARGVRDVDVITPL
CCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ADLRHLRHIALPCLAAFTAASILLAFAARRWLDTKVVRPLDCAMRSVNAIALGELHETIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHEEE
IDESTQARRLFAALAQMQRGLVETLSLVTSEAVAIDDCASHLSSQNQRLASGTESQAAAI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
EQTAATMQQISDGVHRSAHVAAQTNRLADNAATLADESRTRVRAVTDAMDSIARDSRQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVSVVNGLAFRTNILALNAAVEAARAGHQGKGFAVVAAEVRSLAQRSAIAAREIEDLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
NARSAIEKGARLCEDVGTAMDNVVAAAHEVVELSDDMSRSASEQSLGVQQLNEAIKAIDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHH
VTQQNAAMVQHFVETTEDLNGRARALAGAVGAWKLGRDAAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVMTNVRIPAALSIIVGGGLTMTLAVAAAGAVCVDAALTHAEAALWSARGVRDVDVITPL
CCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ADLRHLRHIALPCLAAFTAASILLAFAARRWLDTKVVRPLDCAMRSVNAIALGELHETIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHEEE
IDESTQARRLFAALAQMQRGLVETLSLVTSEAVAIDDCASHLSSQNQRLASGTESQAAAI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
EQTAATMQQISDGVHRSAHVAAQTNRLADNAATLADESRTRVRAVTDAMDSIARDSRQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVSVVNGLAFRTNILALNAAVEAARAGHQGKGFAVVAAEVRSLAQRSAIAAREIEDLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
NARSAIEKGARLCEDVGTAMDNVVAAAHEVVELSDDMSRSASEQSLGVQQLNEAIKAIDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHH
VTQQNAAMVQHFVETTEDLNGRARALAGAVGAWKLGRDAAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]