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The map label for this gene is tctD [H]

Identifier: 116688054

GI number: 116688054

Start: 34950

End: 35627

Strand: Reverse

Name: tctD [H]

Synonym: Bcen2424_0030

Alternate gene names: 116688054

Gene position: 35627-34950 (Counterclockwise)

Preceding gene: 116688055

Following gene: 116688053

Centisome position: 1.02

GC content: 67.85

Gene sequence:

>678_bases
ATGAAACTTTTGCTGGTCGAAGACAACGCCGAGCTCGCGCACTGGATCGTGAACCTGCTGCGCGGCGAGGATTTCGCGGT
CGACTGCGTCGGCGACGGCGAACGGGCCGACACCGTGCTCAAGACCGAACGCTACGACGCGGTGCTGCTCGACATGCGGC
TGCCCGGCATCAGCGGCAAGGAAGTGCTCGCGCGGCTGCGGCGCCGCAACGACAACGTGCCGGTGCTGATGCTGACCGCG
CACGGCTCGGTCGACGACAAGGTCGACTGCTTCGGCGCGGGCGCCGACGACTACGTCGTGAAGCCGTTCGAGTCGCGCGA
GCTGGTGGCGCGCATCCGCGCGCTGATCCGCCGGCAGGCCGGCGTCGGCACGACGCAGCTCGTGTGCGGCGACCTCGTCT
ATGCGTTCGGCACGCGTGAATTCCGCTGCGGCGACGCGGTGCTCGCGCTGCGGCGCCGCGAGCATGCGATCCTCGAAACG
CTGATGCTGCAGCAGAACAAGACGGTATCGAAGGCGCGGCTGATGGACAGCGTGTTCGCGCTCGACGACGAGCCGAGCGC
CGACGCGATCGACATCTACATCCACCGGCTGCGCAAGCATCTCGCCGGCAGCACGGCCGAGATCATCACGCTGCGCGGGC
TCGGCTACATCCTGCGGATGAAGAGCGCGCACGGTTGA

Upstream 100 bases:

>100_bases
CTGGCGCACGGCGGCAGCGCATCGCTCGCGCCGGGGCCCGGCAATCGCGGTGTCGTCGTGACCGTGCGGCTGCCCGCTTT
CGATTGAAGAGAACGCCGTC

Downstream 100 bases:

>100_bases
CGTGGCGCGCTTCCCGCTTTCCACACATCAATTCGTAGCACGAATCATCATTGAAGCCTGCCGGACGTCCGGCAGGATCG
CTTCCACACGCGTGCCCGAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKLLLVEDNAELAHWIVNLLRGEDFAVDCVGDGERADTVLKTERYDAVLLDMRLPGISGKEVLARLRRRNDNVPVLMLTA
HGSVDDKVDCFGAGADDYVVKPFESRELVARIRALIRRQAGVGTTQLVCGDLVYAFGTREFRCGDAVLALRRREHAILET
LMLQQNKTVSKARLMDSVFALDDEPSADAIDIYIHRLRKHLAGSTAEIITLRGLGYILRMKSAHG

Sequences:

>Translated_225_residues
MKLLLVEDNAELAHWIVNLLRGEDFAVDCVGDGERADTVLKTERYDAVLLDMRLPGISGKEVLARLRRRNDNVPVLMLTA
HGSVDDKVDCFGAGADDYVVKPFESRELVARIRALIRRQAGVGTTQLVCGDLVYAFGTREFRCGDAVLALRRREHAILET
LMLQQNKTVSKARLMDSVFALDDEPSADAIDIYIHRLRKHLAGSTAEIITLRGLGYILRMKSAHG
>Mature_225_residues
MKLLLVEDNAELAHWIVNLLRGEDFAVDCVGDGERADTVLKTERYDAVLLDMRLPGISGKEVLARLRRRNDNVPVLMLTA
HGSVDDKVDCFGAGADDYVVKPFESRELVARIRALIRRQAGVGTTQLVCGDLVYAFGTREFRCGDAVLALRRREHAILET
LMLQQNKTVSKARLMDSVFALDDEPSADAIDIYIHRLRKHLAGSTAEIITLRGLGYILRMKSAHG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=38.5321100917431, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=33.4862385321101, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=34.5291479820628, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=31.7180616740088, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.4801762114537, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=31.6742081447964, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=31.3636363636364, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.322869955157, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=35.9649122807018, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=28.6363636363636, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=30.0884955752212, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=28.1818181818182, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=28.3185840707965, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=29.9065420560748, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=29.6296296296296, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=112, Percent_Identity=30.3571428571429, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25058; Mature: 25058

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLVEDNAELAHWIVNLLRGEDFAVDCVGDGERADTVLKTERYDAVLLDMRLPGISGK
CEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCHH
EVLARLRRRNDNVPVLMLTAHGSVDDKVDCFGAGADDYVVKPFESRELVARIRALIRRQA
HHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHHHHHHC
GVGTTQLVCGDLVYAFGTREFRCGDAVLALRRREHAILETLMLQQNKTVSKARLMDSVFA
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LDDEPSADAIDIYIHRLRKHLAGSTAEIITLRGLGYILRMKSAHG
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCC
>Mature Secondary Structure
MKLLLVEDNAELAHWIVNLLRGEDFAVDCVGDGERADTVLKTERYDAVLLDMRLPGISGK
CEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCHH
EVLARLRRRNDNVPVLMLTAHGSVDDKVDCFGAGADDYVVKPFESRELVARIRALIRRQA
HHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHHHHHHC
GVGTTQLVCGDLVYAFGTREFRCGDAVLALRRREHAILETLMLQQNKTVSKARLMDSVFA
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LDDEPSADAIDIYIHRLRKHLAGSTAEIITLRGLGYILRMKSAHG
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]