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The map label for this gene is rssA [H]

Identifier: 116688055

GI number: 116688055

Start: 35641

End: 37008

Strand: Reverse

Name: rssA [H]

Synonym: Bcen2424_0031

Alternate gene names: 116688055

Gene position: 37008-35641 (Counterclockwise)

Preceding gene: 116688056

Following gene: 116688054

Centisome position: 1.06

GC content: 70.39

Gene sequence:

>1368_bases
ATGGCGCACAGCCTGCGCGGGCGGCTCTTGTGGTGGCTGCTGCTGCCGCTCGCGGTGTTCGTGCTGATCGCCGGCGCGAT
GTCGTACGACACCGCGCGGACCACGGCCGCGCTCGTGCAGGACAGCGCGCTCGTCGCATCCGCGCGCACGATCGGCGAGG
ACGTCGAATGGCGTAACGGTCGGCCCGCGGCCGACGTGCCGCCCGCCGCGCTGGAGATCTTCGAATCGCCGTCCGGCGAC
TCGGTGTTCTACAAGGTGATCGACGGCCACGACCGCCTGCTCACCGGCAATCCGGCGCTCGACCTGCCCGCGCGGCACGG
CACCGAGCCGACGCTGTACGACACGTCGCTCGACGGCGTGCCGCTGCGCGCGGTGGCCTACGACCGCCAGCTGTACGACG
AGGGGCAGGTCGAGACGGTCACGGTGGTCGTCGCGAAAACGACGCGTTCGTACGGCGCGATGGTCGCGACGATCTGGCGG
CCGCAACTCGTGCGTCTGTCGCTGATGCTGGTGCTCGCGGTGGTGCTCGTCTATCTCGGCCTCACCTTCGAGCTGCGCCC
GCTGATGAAGCTGAAGGACGACGTGGCCGACCGCGGGCCGATGGAGCTGGAGCCGATCCGCCCCGAGCGGCTCCAGCACG
AGCTGCGGCCGATCGTCGACGCGATCAACCAGTGCATCGCGCGCCTGAACATGCATACGGCCACGCAGCGCCGCTTCATC
GCGGATGCCGCGCACCAGCTGCGCACGCCGATCGCGGTGCTCGATACGCAGATCCAGTACGCGCAGCAGCGCGGCAACGG
CGATCACGAACTCGCGTCCGTGCTCGACAGCATGCAGCGCAGCAGCCGCAAGATGGCGGATGTGACCGACAAGCTGCTGC
TGCTCGCGCATGCGGAAGCGACGCCGTCGACCTTGCTCACCCACCGCGTCGATCTGGCCACCGTGGTGTCGAGCGTGCTG
GAAGAGACGATCGTGCTCGCGCAGCGGCGCGACATCGACCTCGGCGCCGACCTCGGCGAGCGGCTCGACGTCGCGGGCAG
CGACAGCCTGCTCACCGCGCTGGTGATGAACCTCGTCGACAACGCGGTGCGCTACACGCAGCCCGGCGGCTGCGTGACGG
TCTGCGCGCGGCGCGACGGCGACGCAATCGTGCTCGACGTGGTCGACGACGGCCCCGGCATCCCGGCCGAAGCCCGACCG
CACGTATTCAAGCGGTTCTACCGCGTGTCGGCCGATACCGAGGGGTCGGGCCTCGGGCTCGCGATCGTCCGCGAGATCGC
GCTGGCGCACGGCGGCAGCGCATCGCTCGCGCCGGGGCCCGGCAATCGCGGTGTCGTCGTGACCGTGCGGCTGCCCGCTT
TCGATTGA

Upstream 100 bases:

>100_bases
GCGGCGTTCTGAACGCCGCCGGCCGGCGCCTGACATGACATCCCCGACCGCGCCGGCGCCCCCGGCGCGGTTCGGCATTT
CGGAGAAGGAGCGCGAGAGG

Downstream 100 bases:

>100_bases
AGAGAACGCCGTCATGAAACTTTTGCTGGTCGAAGACAACGCCGAGCTCGCGCACTGGATCGTGAACCTGCTGCGCGGCG
AGGATTTCGCGGTCGACTGC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDVEWRNGRPAADVPPAALEIFESPSGD
SVFYKVIDGHDRLLTGNPALDLPARHGTEPTLYDTSLDGVPLRAVAYDRQLYDEGQVETVTVVVAKTTRSYGAMVATIWR
PQLVRLSLMLVLAVVLVYLGLTFELRPLMKLKDDVADRGPMELEPIRPERLQHELRPIVDAINQCIARLNMHTATQRRFI
ADAAHQLRTPIAVLDTQIQYAQQRGNGDHELASVLDSMQRSSRKMADVTDKLLLLAHAEATPSTLLTHRVDLATVVSSVL
EETIVLAQRRDIDLGADLGERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARRDGDAIVLDVVDDGPGIPAEARP
HVFKRFYRVSADTEGSGLGLAIVREIALAHGGSASLAPGPGNRGVVVTVRLPAFD

Sequences:

>Translated_455_residues
MAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDVEWRNGRPAADVPPAALEIFESPSGD
SVFYKVIDGHDRLLTGNPALDLPARHGTEPTLYDTSLDGVPLRAVAYDRQLYDEGQVETVTVVVAKTTRSYGAMVATIWR
PQLVRLSLMLVLAVVLVYLGLTFELRPLMKLKDDVADRGPMELEPIRPERLQHELRPIVDAINQCIARLNMHTATQRRFI
ADAAHQLRTPIAVLDTQIQYAQQRGNGDHELASVLDSMQRSSRKMADVTDKLLLLAHAEATPSTLLTHRVDLATVVSSVL
EETIVLAQRRDIDLGADLGERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARRDGDAIVLDVVDDGPGIPAEARP
HVFKRFYRVSADTEGSGLGLAIVREIALAHGGSASLAPGPGNRGVVVTVRLPAFD
>Mature_454_residues
AHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDVEWRNGRPAADVPPAALEIFESPSGDS
VFYKVIDGHDRLLTGNPALDLPARHGTEPTLYDTSLDGVPLRAVAYDRQLYDEGQVETVTVVVAKTTRSYGAMVATIWRP
QLVRLSLMLVLAVVLVYLGLTFELRPLMKLKDDVADRGPMELEPIRPERLQHELRPIVDAINQCIARLNMHTATQRRFIA
DAAHQLRTPIAVLDTQIQYAQQRGNGDHELASVLDSMQRSSRKMADVTDKLLLLAHAEATPSTLLTHRVDLATVVSSVLE
ETIVLAQRRDIDLGADLGERLDVAGSDSLLTALVMNLVDNAVRYTQPGGCVTVCARRDGDAIVLDVVDDGPGIPAEARPH
VFKRFYRVSADTEGSGLGLAIVREIALAHGGSASLAPGPGNRGVVVTVRLPAFD

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=281, Percent_Identity=34.1637010676157, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786783, Length=295, Percent_Identity=31.5254237288136, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=31.4893617021277, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=30.5555555555556, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790861, Length=288, Percent_Identity=28.125, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=249, Percent_Identity=29.718875502008, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787374, Length=297, Percent_Identity=25.2525252525253, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788279, Length=310, Percent_Identity=26.7741935483871, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.0925925925926, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=26.7782426778243, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787894, Length=219, Percent_Identity=29.2237442922374, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=26.2931034482759, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=249, Percent_Identity=27.3092369477912, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=25.974025974026, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=287, Percent_Identity=28.2229965156794, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=27.9279279279279, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=25.5411255411255, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49382; Mature: 49251

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDVEWRNG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RPAADVPPAALEIFESPSGDSVFYKVIDGHDRLLTGNPALDLPARHGTEPTLYDTSLDGV
CCCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEECCCCCC
PLRAVAYDRQLYDEGQVETVTVVVAKTTRSYGAMVATIWRPQLVRLSLMLVLAVVLVYLG
CCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
LTFELRPLMKLKDDVADRGPMELEPIRPERLQHELRPIVDAINQCIARLNMHTATQRRFI
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAAHQLRTPIAVLDTQIQYAQQRGNGDHELASVLDSMQRSSRKMADVTDKLLLLAHAEA
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
TPSTLLTHRVDLATVVSSVLEETIVLAQRRDIDLGADLGERLDVAGSDSLLTALVMNLVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
NAVRYTQPGGCVTVCARRDGDAIVLDVVDDGPGIPAEARPHVFKRFYRVSADTEGSGLGL
HHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHH
AIVREIALAHGGSASLAPGPGNRGVVVTVRLPAFD
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
AHSLRGRLLWWLLLPLAVFVLIAGAMSYDTARTTAALVQDSALVASARTIGEDVEWRNG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RPAADVPPAALEIFESPSGDSVFYKVIDGHDRLLTGNPALDLPARHGTEPTLYDTSLDGV
CCCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEECCCCCC
PLRAVAYDRQLYDEGQVETVTVVVAKTTRSYGAMVATIWRPQLVRLSLMLVLAVVLVYLG
CCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
LTFELRPLMKLKDDVADRGPMELEPIRPERLQHELRPIVDAINQCIARLNMHTATQRRFI
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAAHQLRTPIAVLDTQIQYAQQRGNGDHELASVLDSMQRSSRKMADVTDKLLLLAHAEA
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
TPSTLLTHRVDLATVVSSVLEETIVLAQRRDIDLGADLGERLDVAGSDSLLTALVMNLVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
NAVRYTQPGGCVTVCARRDGDAIVLDVVDDGPGIPAEARPHVFKRFYRVSADTEGSGLGL
HHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHH
AIVREIALAHGGSASLAPGPGNRGVVVTVRLPAFD
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA