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The map label for this gene is murI [H]

Identifier: 116626345

GI number: 116626345

Start: 9167833

End: 9168591

Strand: Direct

Name: murI [H]

Synonym: Acid_7305

Alternate gene names: 116626345

Gene position: 9167833-9168591 (Clockwise)

Preceding gene: 116626342

Following gene: 116626364

Centisome position: 91.99

GC content: 66.01

Gene sequence:

>759_bases
ATGATCGGCGTGTTCGATTCGGGAGTCGGCGGCTTGACGGTCTTGCAGGCGTTGCGCAAGCGGCTGCCGCAGCGTGAATT
TCTATACGTGGGCGACACGGCGCGCGCGCCGTATGGCCGTAAGCCGGCGGCAATGGTGGCGGGCTTCGCGTGCGAGATTG
CGGATTATCTGTGCGGCCGCGGCGTGGAGGCGATCGTGGTGGCGTGTAACACCGCCTCGGCTGTGGCCCTGCCGGAATTG
GAACGCCGCTGCAAGGTCCCGGTGTGGGGCGTGGTGGACGCAGGTGTGGAAGCGGCGACACGCATGACGCGCACGGGTCA
CATCGGTGTGATCGCGACCCGTGCGACGATTGCGAGCGCGGCCTACCAGCGGCGGCTGGAAGCGCGCGGACTGCGCGTGT
GGGCTCGCGAATGTCCGATGCTGGTACACCTGGTGGAAGAGGGTCTCGCGGAATCGGAGGAGGCGGACGTGCTCTCGCGG
CATTACCTCAGCGGGCGGCCCGAGATCGACACTTTGATTCTGGGATGCACGCACTATCCGCTGCTGAGGGCATCATTGCA
GCGCGCTGCAGGTGGGCATGTGCGCCTGGTGGATAGCGCGAGTGTCACGGCGGAGCGAGTAGCCGCGGCGATGACAGACG
AAGGGAATGGACGTGTCACATACTATGCGACAGGCGACACGAAGGCATTCGCGCACACCGCGCGGATGATGGGAGAAGGT
CACGCGGTGCACGCCATCGAACTCCGCGACGCGGCGTGA

Upstream 100 bases:

>100_bases
CCCTGCGGGTCGAGAACGGTGGACTTGAGAGTGACGAAGACGCGAGCTTTCATGAAGATCTCTAATTATGACATGGCAGC
GTACGTGCAGTTGATGCGGC

Downstream 100 bases:

>100_bases
GGGTTAACGTTTTTGCGCGGGGTCGGCCTTAGGCCAGACTGGGCTTGCCAGTTCGATGCGCCAGATCGGACCGCCTTCGA
ACAACGGGCCTTCCGACTTC

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MIGVFDSGVGGLTVLQALRKRLPQREFLYVGDTARAPYGRKPAAMVAGFACEIADYLCGRGVEAIVVACNTASAVALPEL
ERRCKVPVWGVVDAGVEAATRMTRTGHIGVIATRATIASAAYQRRLEARGLRVWARECPMLVHLVEEGLAESEEADVLSR
HYLSGRPEIDTLILGCTHYPLLRASLQRAAGGHVRLVDSASVTAERVAAAMTDEGNGRVTYYATGDTKAFAHTARMMGEG
HAVHAIELRDAA

Sequences:

>Translated_252_residues
MIGVFDSGVGGLTVLQALRKRLPQREFLYVGDTARAPYGRKPAAMVAGFACEIADYLCGRGVEAIVVACNTASAVALPEL
ERRCKVPVWGVVDAGVEAATRMTRTGHIGVIATRATIASAAYQRRLEARGLRVWARECPMLVHLVEEGLAESEEADVLSR
HYLSGRPEIDTLILGCTHYPLLRASLQRAAGGHVRLVDSASVTAERVAAAMTDEGNGRVTYYATGDTKAFAHTARMMGEG
HAVHAIELRDAA
>Mature_252_residues
MIGVFDSGVGGLTVLQALRKRLPQREFLYVGDTARAPYGRKPAAMVAGFACEIADYLCGRGVEAIVVACNTASAVALPEL
ERRCKVPVWGVVDAGVEAATRMTRTGHIGVIATRATIASAAYQRRLEARGLRVWARECPMLVHLVEEGLAESEEADVLSR
HYLSGRPEIDTLILGCTHYPLLRASLQRAAGGHVRLVDSASVTAERVAAAMTDEGNGRVTYYATGDTKAFAHTARMMGEG
HAVHAIELRDAA

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis [H]

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family [H]

Homologues:

Organism=Escherichia coli, GI87082355, Length=224, Percent_Identity=38.3928571428571, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.1.3 [H]

Molecular weight: Translated: 27000; Mature: 27000

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00923 ASP_GLU_RACEMASE_1 ; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGVFDSGVGGLTVLQALRKRLPQREFLYVGDTARAPYGRKPAAMVAGFACEIADYLCGR
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
GVEAIVVACNTASAVALPELERRCKVPVWGVVDAGVEAATRMTRTGHIGVIATRATIASA
CCEEEEEEECCCCEEECHHHHHHCCCCEEEEHHCCHHHHHHHHCCCCEEEEEHHHHHHHH
AYQRRLEARGLRVWARECPMLVHLVEEGLAESEEADVLSRHYLSGRPEIDTLILGCTHYP
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHEEEECCCCHH
LLRASLQRAAGGHVRLVDSASVTAERVAAAMTDEGNGRVTYYATGDTKAFAHTARMMGEG
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCC
HAVHAIELRDAA
CEEEEEEEECCC
>Mature Secondary Structure
MIGVFDSGVGGLTVLQALRKRLPQREFLYVGDTARAPYGRKPAAMVAGFACEIADYLCGR
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
GVEAIVVACNTASAVALPELERRCKVPVWGVVDAGVEAATRMTRTGHIGVIATRATIASA
CCEEEEEEECCCCEEECHHHHHHCCCCEEEEHHCCHHHHHHHHCCCCEEEEEHHHHHHHH
AYQRRLEARGLRVWARECPMLVHLVEEGLAESEEADVLSRHYLSGRPEIDTLILGCTHYP
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHEEEECCCCHH
LLRASLQRAAGGHVRLVDSASVTAERVAAAMTDEGNGRVTYYATGDTKAFAHTARMMGEG
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCC
HAVHAIELRDAA
CEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA